Abstract
The first-line treatment for patients suffering from epilepsy is pharmacological therapy with antiepileptic drugs (AEDs). However, 20–30% of patients with epilepsy are resistant to medical treatment, despite efforts to find effective combination therapy (Lowenstein 2008). For patients who suffer from pharmacoresistant, localization-related epilepsy, resective surgery offers the best chance for a reduction in seizure activity or a lifetime free of seizures. The focus of this chapter will highlight the presurgical evaluation, imaging technologies, and intraoperative monitoring techniques used to aid surgical teams carry out successful procedures designed to help both adult and pediatric patients afflicted with intractable epilepsy.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Go, C., and Snead, O. (2008) Pharmacologically intractable epilepsy in children: diagnosis and preoperative evaluation. Neurosurg. Focus 25:1–7
Ferrie, C., Agathonikou, A., and Panayiotopoulos, C. (1998) Electroencephalography and video-electroencephalography in the classification of childhood epilepsy syndromes. J R Soc Med 91:251–259
Schuh, L., and Drury, I. (1997) Intraoperative electrocorticography and direct cortical electrical stimulation Seminars in Anesthesia 16:46–55
Kliegman, R., et al. (2006) Nelson’s essentials of Pediatrics Phila Elsevier Saunders 5t ed., pp 834-835, 839–840
Lowenstein, D (2008) Seizures and epilepsy. In Fauci, A., et al. eds Harrison’s Principles of Internal Medicine. N.Y. McGraw Hill Medical 17th ED., 2490t, 2498–2510
Nordi, D., and Pedley, T. (2008) The Use of Electroencephalography in the Diagnosis of Epilepsy in Childhood. In Pellock, J, Bourgeois, B., and Dodson, W. eds Pediatric Epilepsy, 3rd ed New York, Demos pp 213-226
Johnston, J., Smyth, M., and McKinstry, R. (2008) Basics of Neuroimaging in Pediatric Epilepsy in Pellock, J., Bourgeois, B., and Dodson, W. eds Pediatric Epilepsy, 3rd ed., New York, Demos pp 213–226
Passaro, E., and Jobe, K. (2010) Identification of Potential Epilepsy Surgery Candidates. eMedicne 1–19 (http://emedicine.medscape.com?article/2514491185203
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2012 Springer Science+Business Media, LLC
About this chapter
Cite this chapter
McCandless, D.W. (2012). Diagnostic Technology. In: Epilepsy. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-0361-6_26
Download citation
DOI: https://doi.org/10.1007/978-1-4614-0361-6_26
Published:
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4614-0108-7
Online ISBN: 978-1-4614-0361-6
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)