Juvenile myoclonic epilepsy is a common form of generalized idiopathic epilepsy which usually has an onset between about 12 and 18 years of age, hence its name. The seizure types which may be seen include myoclonic jerks and seizures, absence seizures, and tonic clonic seizures (Zifkin et al. 2005). The seizures usually occur during daytime, but can occur upon awakening. Clinical examination does not reveal any focal neurological signs, and MRI shows no definitive characteristic anatomical lesions. Psychiatric examination does show a specific personality pattern in about 15% of patients which consists of low self-esteem, emotional instability, lack of discipline, mood changes, etc.
KeywordsPurkinje Cell Status Epilepticus Sodium Current Absence Seizure Heterozygous Mouse
- Dravet, C., et al. (1992) Severe myoclonic epilepsy in infants. IN Roger, J., et al. Eds. Epileptic Syndromes in Infancy, Childhood, and Adolescence. London, J. Libby pp 75-88Google Scholar
- Pennacchio, L., et al. (1998) Progressive ataxia, myoclonic epilepsy, and cerebellar apoptosis in cystatin B deficient mice. Nature 20:251–258Google Scholar
- Koskiniemi, M. (1990) Myoclonic Epilepsy. In Pediatric Epilepsy. Sillanpaa, M., et al. eds. Wrightson, HampshireGoogle Scholar