Skip to main content

Automatic Acquisition and Processing of Large Sets of Holographic Measurements in Medical Research

  • Conference paper
  • First Online:

Abstract

We are developing an advanced computer-controlled digital opto-electronic holographic system (DOEHS) with the ability to operate in several modalities, including optoelectronic holographic microscopy, lensless digital holography, speckle pattern interferometry, and fringe projection. The DOEHS is being designed for medical applications requiring full-field-of-view information of shape and deformations to aid in the diagnosis and investigation of specific disorders. Particular features of the DOEHS include the capabilities to rapidly acquire and quantitatively process a relatively large amount of interferometric data. Therefore, automatic procedures for acquisition of images or video, computation and application of quality metrics, and phase unwrapping are applied with minimal user interaction. The results are catalogued with relevant metadata in a database allowing for massive analysis and comparison between subjects or patients. Currently, the DOEHS is being developed to measure acoustically induced deformations of the eardrum of several species, including humans. Measurements are used in diagnosing middle-ear conductive disorders and investigating the causes of failure of middle-ear surgical procedures. We present representative measurement procedures and results.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD   219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Shortliffe, E.H. and Barnett, G. O. “Medical data: their acquisition, storage, and use,” Medical informatics: computer applications in health care, Edward H. Shortliffe, Leslie E. Perreault, Gio Wiederhold, and Lawrence M. Fagan (Eds.). Addison-Wesley Longman, Boston, pp 37-69, 1990.

    Google Scholar 

  2. Brooks, R., Grotz, C.. “Implementation Of Electronic Medical Records: How Healthcare Providers Are Managing The Challenges Of Going Digital.” JBER, 8, Dec. 2010.

    Google Scholar 

  3. Rosowski, J. J., “Models of external- and middle- ear function,” Auditory computation, Hawkins, H. L., McMullen, T. A., Popper A. N., and Fay, R. R., eds, Springer-Verlag, New York, pp 15-60, 1996.

    Google Scholar 

  4. Rosowski, J. J., Cheng, J. T., Ravicz, M. E., Hulli, N., Hernandez-Montes, M., Harrington, E., Furlong, C., “Computer-assisted time-averaged holograms of the motion of the surface of the mammalian tympanic membrane with sound stimuli of 0.4–25 kHz”, Hear. Res.253: 83–96, 2009.

    Article  Google Scholar 

  5. Whittemore, K. R., Merchant, S. N., Poon B. B., and Rosowski, J. J., “A normative study of tympanic membrane motion in humans using a laser Doppler vibrometer (LDV)”, Hear. Res. 187(1-2):85-104, 2004.

    Article  Google Scholar 

  6. Hulli, N., Development of an optoelectronic holographic otoscope system for characterization of sound-induced displacements in tympanic membranes, Department of Mechanical Engineering, Worcester Polytechnic Institute, Worcester, MA, 2008.

    Google Scholar 

  7. Hernández-Montes, M., Furlong, C., Rosowski, J. J., Hulli, N., Harrington, E., Cheng, J. T., Ravicz, M. E., and Santoyo, M., “Optoelectronic holographic otoscope for measurement of nanodisplacements in tympanic membranes,” J Biomed Opt.; 14(3), 1-1–1-9 2009.

    Google Scholar 

  8. Dobrev, I., Balboa, M., Fossett, R., Furlong, C., Harrington, E., “MEMS for real-time infrared imaging,” Proc. SEM, In Press, 2011.

    Google Scholar 

  9. Harrington, E., Dobrev, I., Bapat, N., Flores, J. M., Furlong, C., Rosowski, J. J., Cheng, J. T., Scarpino, C., Ravicz, M., “Development of an optoelectronic holographic platform for otolaryngology applications,” Proc. SPIE, 7791, 2010.

    Google Scholar 

  10. Bushman, T., Gennert, M.A., Pryputniewicz, R.J., “Phase unwrapping by least squares error minimization of phase curvature,” Computer Science, Worcester Polytechnic Institute, Worcester, MA, 1993.

    Google Scholar 

  11. Giglia, D., Pritt, M., Two-Dimensional Phase Unwrapping. Wiley, New York, 1998.

    Google Scholar 

  12. Matlab, The MathWorks, Inc., Natick, MA.

    Google Scholar 

  13. Furlong C., Hernández-Montes, M. S., Hulli, N., Cheng, J. T., Ravicz M. E., and Rosowski J. J., “Development of an optoelectronic holographic otoscope for characterization of sound-induced displacements in tympanic membranes,” Proc. 31st Midwinter Meeting of the ARO, Phoenix AZ, 2008.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2011 Springer Science+Businees Media, LLC

About this paper

Cite this paper

Harrington, E., Furlong, C., Rosowski, J.J., Cheng, J.T. (2011). Automatic Acquisition and Processing of Large Sets of Holographic Measurements in Medical Research. In: Proulx, T. (eds) Optical Measurements, Modeling, and Metrology, Volume 5. Conference Proceedings of the Society for Experimental Mechanics Series. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-0228-2_26

Download citation

  • DOI: https://doi.org/10.1007/978-1-4614-0228-2_26

  • Published:

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4614-0227-5

  • Online ISBN: 978-1-4614-0228-2

  • eBook Packages: EngineeringEngineering (R0)

Publish with us

Policies and ethics