Abstract
High throughput microarray technologies were developed nowadays. By using these new technologies, tremendous amount of gene expression data were accumulated in a short time. These data can help us to analyze the complex relationship of gene interactions. DNA microarray is an orderly arrangement of many oligonucleotides or identified sequenced genes printed on an impermeable solid support, usually glass, silicon chips or high-polymer material [1]. DNA microarray is also called DNA chip, gene chip, or biochip. The biochip is an integration of several technologies, including automated DNA sequencing, DNA amplification by PCR, oligonucleotide synthesis, nucleic acid labeling chemistries and bioinformatics. Microarrays have become standard tools for gene expression measurement in biology and biomedicine [2, 3, 4]. The application ranges from gene expression changes of the cell cycle over the classification of disease to drug design.
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Acknowledgments
This work was supported in part from the National Science Council, Taiwan (Project No. 95-2745-E-468-001-URD, Project No. 95-2745-E-468-003-URD, and Project No. NSC 99-2221-E-024-010]. We also thank SMD (Stanford MicroArray Database) and KEGG (Kyoto Encyclopedia of Genes and Genomes) for their valuable databases.
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Ou, JW., Chen, RM., Hu, RM., Hsu, CY., Tsai, J.J. (2011). A SYSTEMATIC GENE EXPRESSION EXPLORER TOOL FOR MULTIPLE AND PAIRED CHIPS. In: Suh, S., Gurupur, V., Tanik, M. (eds) Biomedical Engineering. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-0116-2_11
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DOI: https://doi.org/10.1007/978-1-4614-0116-2_11
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