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Particle Simulations of Growth: Application to Angiogenesis

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Modeling Tumor Vasculature

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Abstract

We apply the particle-based framework developed in the previous chapter to develop continuum and discrete-continuum models of sprouting angiogenesis under consideration of a detailed tumor microenvironment. We present results on the vessel development as a function of the extracellular matrix and different VEGF isoforms.

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Authors and Affiliations

  1. Chair of Computational Science, ETH Zurich, Zurich, CH-8092, Switzerland

    Florian Milde, Michael Bergdorf & Petros Koumoutsakos

Authors
  1. Florian Milde
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  2. Michael Bergdorf
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  3. Petros Koumoutsakos
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Corresponding author

Correspondence to Petros Koumoutsakos .

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Editors and Affiliations

  1. Dept. Mathematics, University of Michigan, 530 Church Street, Ann Arbor, Michigan, 48109, USA

    Trachette L. L. Jackson

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Milde, F., Bergdorf, M., Koumoutsakos, P. (2012). Particle Simulations of Growth: Application to Angiogenesis. In: Jackson, T.L. (eds) Modeling Tumor Vasculature. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-0052-3_12

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