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Testis

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Color Atlas of Fetal and Neonatal Histology

Abstract

During the embryonic period, the microscopic anatomy of the testis is formed. The first step in the maturation of germ cells, the transformation of primordial germ cells into gonocytes, takes place. Sertoli cells and Leydig cells differentiate from their progenitors. The Sertoli cells produce Müllerian-inhibiting substance, which will cause regression of the paramesonephric ducts. The Leydig cells produce testosterone, which will cause masculinization of the internal and external genitalia. The embryonic testis begins its control of male sexual differentiation.

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Acknowledgments

The author thanks Dr. Catherine T.-S. Chung from The Hospital for Sick Children, Toronto, Canada, for invaluable assistance in selecting microscopic slides for photography, taking photomicrographs, and editing the manuscript.

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Authors and Affiliations

  1. Department of Pathology and Laboratory Medicine, The Children’s Hospital of Philadelphia, Philadelphia, USA

    Dale S. Huff MD (Senior Pathologist)

  2. Department of Pathology and Laboratory Medicine, The University of Pennsylvania School of Medicine, Philadelphia, USA

    Dale S. Huff MD (Associate Professor)

Authors
  1. Dale S. Huff MD
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Editor information

Editors and Affiliations

  1. Feinberg School of Medicine, Department of Pathology, Northwestern University, 710 N. Fairbanks Court, Chicago, 60611, Illinois, USA

    Linda M. Ernst

  2. Dept. Pathology, Children's Hospital Philadelphia, 324 South 34th St, Philadelphia, 19104, Pennsylvania, USA

    Eduardo D. Ruchelli

  3. Dept. Pathology, Children's Hospital Philadelphia, 324 South 34th St, Philadelphia, 19104, Pennsylvania, USA

    Dale S. Huff

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Huff, D.S., Huff, D.S. (2011). Testis. In: Ernst, L., Ruchelli, E., Huff, D. (eds) Color Atlas of Fetal and Neonatal Histology. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-0019-6_9

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  • DOI: https://doi.org/10.1007/978-1-4614-0019-6_9

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4614-0018-9

  • Online ISBN: 978-1-4614-0019-6

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