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The Influence of Dietary Fatty Acid Composition on Lipogenesis

  • Chapter
Advances in Nutritional Research

Part of the book series: Advances in Nutritional Research ((ANUR))

Abstract

The steps involved in the conversion of nonlipid precursors into lipid are illustrated in Fig. 1 a. These steps may be conveniently divided into four parts:

  1. 1.

    Generation of cytoplasmic acetyl-CoA.

  2. 2.

    Conversion of acetyl-CoA to fatty acyl-CoA, predominantly palmitoylCoA.

  3. 3.

    Incorporation of fatty acyl-CoA into triglyceride.

  4. 4.

    Generation of NADPH for fatty acid synthesis by fatty acid synthetase.

Lipid synthesis and its regulation have been the subject of a number of recent reviews (Geelen et al.,1980; Freedland and Szepesi, 1971; Numa, 1974; Numa and Yamashita, 1974; Romsos and Leveille, 1974; Volpe and Vagelos, 1976). Readers who desire a more detailed treatment than presented below are advised to consult one or more of these reviews.

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  1. Department of Biochemistry, Memorial University of Newfoundland, St. John’s, Newfoundland, AlB 3X9, Canada

    Gene R. Herzberg

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  1. Gene R. Herzberg
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  1. University of Guelph, Guelph, Ontario, Canada

    Harold H. Draper

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Herzberg, G.R. (1983). The Influence of Dietary Fatty Acid Composition on Lipogenesis. In: Draper, H.H. (eds) Advances in Nutritional Research. Advances in Nutritional Research. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-9937-7_10

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  • DOI: https://doi.org/10.1007/978-1-4613-9937-7_10

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