Abstract
The last quarter of a century has seen many spectacular developments in medicine, one of which has been the rise of psychopharmacology or the use of drugs to change behavior and emotions. The initial discoveries were an accidental offshoot of work with antihistamine drugs in the 1940s, and clinical use was largely empirical at first. However, in the last decade, as a result of close study of these drugs coupled with better measurement techniques and improved understanding of brain function, there has been a marked change in the nature and direction of psychopharmacology from empiricism to a true science. Perhaps the best illustration of this change can be seen in the recent discovery of the morphinelike peptides called enkephalins. Within the last 5 years, not only has the site of action of these substances been identified, but the precise molecular structure and the effects of slight changes in a single amino acid in the molecule have been delineated (Treager & Coghlan, 1980).
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Werry, J.S. (1982). Pharmacotherapy. In: Lahey, B.B., Kazdin, A.E. (eds) Advances in Clinical Child Psychology. Advances in Clinical Child Psychology, vol 5. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-9811-0_8
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