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The Placenta in Multiple Pregnancy

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Pathology of Multiple Pregnancy

Abstract

The pathologist’s contribution to the analysis of multiple pregnancy is twofold—surgical pathology of the placentation, and autopsy pathology of any deceased fetus(es) or infant(s). The easiest and most obvious examination is documentation of placental morphology, but unfortunately this is still often quite incomplete

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References

  1. Kloosterman GJ. The “Third Circulation” in identical twins. Ned Tijdschr Verlosk Gynaecol. 1963; 63:395–412.

    CAS  Google Scholar 

  2. Strong SJ, Corney G. The Placenta in Twin Pregnancy. Norwich: Pergamon Press; 1967.

    Google Scholar 

  3. Boyd JD, Hamilton WJ. The Human Placenta. Cambridge: W Heffer; 1970:313–334.

    Google Scholar 

  4. Benirschke K, Driscoll SG. The Pathology of the Human Placenta. New York: Springer-Verlag; 1967; 1–179.

    Google Scholar 

  5. Potter EL, Craig JM. Pathology of the Fetus and the Infant. 3rded. Chicago: Year Book; 1975:207–237.

    Google Scholar 

  6. Fox H. Pathology of the placenta. In: Bennington JL, ed. Major Problems in Pathology. Vol 7. London: WB Saunders; 1978:73–94.

    Google Scholar 

  7. Shanklin DR, Perrin EVDK. Multiple gestation. In: Perrin EVDK, ed. Pathology of the Placenta. Contemporary Issues in Surgical Pathology. Vol 5. Roth LM, series ed. New York: Churchill-Livingstone; 1984:165–182.

    Google Scholar 

  8. Benirschke K, Kaufmann P. Pathology of the Human Placenta. 2nd ed. New York: Springer-Verlag; 1990:636–753.

    Google Scholar 

  9. Corey LA, Nance WE, Kang KW, Christian JC. Effects of type of placentation on birth weight and its variability in monozygotic and dizygotic twins. Acta Genet Med Gemellol. 1979;28:41–50.

    PubMed  CAS  Google Scholar 

  10. Buzzard IM, Uchida IA, Norton JA, Christian JC. Birth weight and placental proximity in like-sex twins. Am J Hum Genet. 1983;35:318–323.

    PubMed  CAS  Google Scholar 

  11. Cameron AH. The Birmingham twin survey. Roy Soc MedProc. 1968;61:229–234.

    CAS  Google Scholar 

  12. Bhargava I, Chakravarty A. Vascular anastomoses in twin placentas, and their recognition. Acta Anat. 1975;93:471–480.

    Article  PubMed  CAS  Google Scholar 

  13. Arts NFTh. Investigations on the vascular system of the placenta. Part I. General introduction and the fetal vascular system. Am J Obstet Gynecol. 1961;82:147–158.

    PubMed  CAS  Google Scholar 

  14. Cameron AH, Edwards JH, Derom R, Thiery M, Boelaert R. The value of twin surveys in the study of malformations. Eur J Obstet Gynec Reprod Biol. 1983;14:347–356.

    Article  CAS  Google Scholar 

  15. Robertson EG, Neer KJ. Placental injection studies in twin gestation. Am J Obstet Gynecol. 1983; 147:170–174.

    PubMed  CAS  Google Scholar 

  16. Benirschke K, Kim CK. Multiple pregnancy. N Engl J Med. 1973;288:1276–1284 1329–1336.

    Article  PubMed  CAS  Google Scholar 

  17. Corney G, Robson EB. Types of twinning and determination of zygosity. In: MacGillivray I, Nylander PPS, Corney G, eds. Human Multiple Reproduction. Philadelphia: WB Saunders; 1975:16–39.

    Google Scholar 

  18. Corner GW. The observed embryology of human single ovum twins and other multiple births. Am J Obstet Gynecol. 1955;70:933–951.

    PubMed  CAS  Google Scholar 

  19. Fujikura T, Froehlich LA. Twin placentation and zygosity. Obstet Gynecol. 1971;37:34–43.

    PubMed  CAS  Google Scholar 

  20. Bulmer MG. The Biology of Twinning in Man. Oxford: Clarendon Press; 1970.

    Google Scholar 

  21. Ramos-Arroyo MA, Ulbright TM, Yu P-L, Christian JC. Twin study: relationship between birth weight, zygosity, placentation, and pathologic placental changes. Acta Genet Med Gemellol. 1988; 37:229–238.

    PubMed  CAS  Google Scholar 

  22. Corney G. Placentation. In: MacGillivray I, Nylander PPS, Corney G, eds. Human Multiple Reproduction. Philadelphia: WB Saunders; 1975:40–76.

    Google Scholar 

  23. Nylander PPS, Osunkoya BO. Unusual monochori- onic placentation with heterosexual twins. Obstet Gynecol. 1970;36:621–625.

    PubMed  CAS  Google Scholar 

  24. Kim K, Lage JM. Bipartite diamnionic monochorionic twin placenta with superficial vascular anastomoses: report of a case. Hum Pathol. 1991;22:501–503.

    Article  PubMed  CAS  Google Scholar 

  25. Gilbert WM, Davis SE, Kaplan C, Pretorius D, Merritt TA, Benirschke K. Morbidity associated with prenatal disruption of the dividing membrane in twin gestations. Obstet Gynecol. 1991;78:623–630.

    CAS  Google Scholar 

  26. Pauls F. Monoamniotic twin pregnancy. A review of the world literature and a report of two new cases. Can Med Assoc J. 1969;100:254–256.

    PubMed  CAS  Google Scholar 

  27. Nylander PPS. The value of the placenta in the determination of zygosity—a study of 1,052 Nigerian twin maternities. J Obstet Gynecol Br Cwlth. 1969;76:699–704.

    Article  CAS  Google Scholar 

  28. Soma H, Yoshida K, Tada M, Mukaida T, Kikuehi T. Fetal abnormalities associated with twin placentation (abstract). Teratology. 1975;12:211.

    Google Scholar 

  29. James WH. Sex ratio and placentation in twins. Ann Hum Biol. 1980;7:273–276.

    Article  PubMed  CAS  Google Scholar 

  30. Ward BS. Cellular growth of the placenta in twin pregnancy late in gestation. Placenta. 1985;6:107–116.

    Article  PubMed  CAS  Google Scholar 

  31. Naeye RL. Do placental weights have clinical significance? Hum Pathol. 1987;18:387–391.

    Article  PubMed  CAS  Google Scholar 

  32. Stiller RJ, Lockwood CJ, Belanger K, Baumgarten A, Hobbins JC, Mahoney MJ. Amniotic fluid a-fe- toprotein concentrations in twin gestations: dependence on placenta membrane anatomy. Obstet Gynecol. 1988;158:1088–1092.

    CAS  Google Scholar 

  33. Benirschke K. Placental morphogenesis. In: Wynn RM, ed. Fetal Hemostasis. Vol 1: Proceedings of the First Conference. New York: New York Academy of Sciences; 1965;217–265.

    Google Scholar 

  34. Jauniaux E, Elkazen N, Leroy F, Wilkin P, Rodesh F, Hustin J. Clinical and morphologic aspects of the vanishing twin phenomenon. Obstet Gynecol. 1988;72:577–581.

    PubMed  CAS  Google Scholar 

  35. Benirschke K, Kaufmann P. Pathology of the Human Placenta. 2nd ed. New York: Springer-Verlag; 1990:199–204.

    Google Scholar 

  36. Robinson LK, Jones KL, Benirschke K. The nature of structural defects associated with velamentous and marginal insertion of the umbilical cord. Am J Obstet Gynecol. 1983;146:191–193.

    PubMed  CAS  Google Scholar 

  37. Ottolenghi-Preti GF. Sopra un rarissimo caso di gravidanza gemellare con un feto papiraceo e con inserzione velamentosa del funiculo del feto vivo. An Ostet Ginecol Med Perinat. 1972;93:173–199.

    CAS  Google Scholar 

  38. Sekiya S, Hafez ESE. Physiomorphology of twin transfusion syndrome: a study of 86 twin gestations. Obstet Gynecol. 1977;50:288–292.

    PubMed  CAS  Google Scholar 

  39. Heifetz SA. Single umbilical artery. A statistical analysis of 237 autopsy cases and review of the literature. Perspect Pediatr Pathol. 1984;8:345–378.

    PubMed  CAS  Google Scholar 

  40. Duerbeck NB, Pietrantoni M, Reed KL, Anderson CF, Shenker L. Doppler flow velocities in single umbilical arteries. Am J Obstet Gynecol. 1991; 165:1120–1122.

    PubMed  CAS  Google Scholar 

  41. Soernes T, Bakke T. The length of the human umbilical cord in twin pregnancies. Am J Obstet Gynecol. 1987;157:1229–1230.

    PubMed  CAS  Google Scholar 

  42. De Silva N. Zygosity and umbilical cord length. J Reprod Med 1992;37(10):850–852.

    PubMed  Google Scholar 

  43. Naeye RL. Umbilical cord length: clinical significance. J Pediatr. 1985;107:278–281.

    Article  PubMed  CAS  Google Scholar 

  44. Lacro RV, Jones KL, Benirschke K. The umbilical cord twist: origin, direction and relevance. Am J Obstet Gynecol. 1987;157:833–838.

    PubMed  CAS  Google Scholar 

  45. Boyd JD, Hamilton WJ. The Human Placenta. Cambridge: W Heffer; 1970:222–227.

    Google Scholar 

  46. Benirschke K. The placenta in twin gestation. Clin Obstet Gynecol. 1990;33:18–31.

    Article  PubMed  CAS  Google Scholar 

  47. La Vecchia C, Franceschi S, Fasdli M, Magioni C. Gestational trophoblastic neoplasms in homozygous twins. Obstet Gynecol. 1982;60:250–252.

    PubMed  Google Scholar 

  48. De George FV. Hydatidiform moles in other pregnancies of mothers of twins. Am J Obstet Gynecol. 1970;108:369–371.

    PubMed  Google Scholar 

  49. Mayer CF. Sextuplets and higher multiparous births: a Critical review of history and legend from Aristoteles to the 20th Century. Acta Genet Med Gemellol. 1952;1:118–135 242–275.

    PubMed  CAS  Google Scholar 

  50. Szulman AE, Surti U. The syndromes of partial and complete molar gestation. Clin Obstet Gynecol. 1984;27:172–180.

    Article  PubMed  CAS  Google Scholar 

  51. Shanklin DR. Tumors of the Placenta and Umbilical Cord. Philadelphia: BC Decker; 1990:24–29.

    Google Scholar 

  52. Beischer NA. Hydatidiform mole with coexistent foetus. Aust NZ J Obstet Gynecol. 1966;6:127–141.

    Article  CAS  Google Scholar 

  53. Yee B, Tu B, Piatt LD. Coexisting hydatidiform mole with a live fetus presenting as a placenta previa on ultrasound. Am J Obstet Gynecol. 1982;144:726–728.

    PubMed  CAS  Google Scholar 

  54. Fisher RA, Sheppard DM, Lawler SD. Twin pregnancy with complete hydatidiform mole (46, XX) and fetus (46, XY): genetic origin proved by analysis of chromosome polymorphisms. Br Med J. 1982;284:1218–1220.

    Article  CAS  Google Scholar 

  55. Sauerbrei EE, Salem S, Fayle B. Coexistent hydatidiform mole and live fetus in the second trimester. Radiology. 1980;135:415–417.

    PubMed  CAS  Google Scholar 

  56. Hohe PT, Cochrane CR, Gemlich JT, Austin JA. Coexistent trophoblastic tumor and viable pregnancy. Obstet Gynecol. 1971;38:899–904.

    PubMed  CAS  Google Scholar 

  57. Ladehoff P, Maruszczak A. A pregnancy with a hydatidiform mole, thyrotoxicosis and live born infant. Acta Obstet Gynecol Scand. 1978;57:477–478.

    Article  PubMed  CAS  Google Scholar 

  58. Suzuki M, Matsunoba A, Wakita K, Nishijima M, Osanai K. Hydatidiform mole with a surviving coexistent fetus. Obstet Gynecol. 1980;56:384–388.

    PubMed  CAS  Google Scholar 

  59. Vejerslev LO. Clinical management and diagnostic possibility in hydatidiform mole with coexistent fetus. Obstet Gynecol Survey. 1991;46:577–588.

    Article  CAS  Google Scholar 

  60. Deaton JL, Hoffman JS, Saal H, Allred C, Koulos JP. Molar pregnancy coexisting with a normal fetus: a case report. Gynecol Oncol. 1989;32:394–397.

    Article  PubMed  CAS  Google Scholar 

  61. Feinberg RF, Lockwood CJ, Salafia C, Hobbins JC. Sonographic diagnosis of a pregnancy with a diffuse hydatidiform mole and coexistent 46, XX fetus: a case report. Obstet Gynecol. 1988;72:485–488.

    PubMed  CAS  Google Scholar 

  62. Vejerslev LO, Sunde L, Hansen BF, Larsen JK, Christensen IJ, Larsen G. Hydatidiform mole and fetus with normal karyotype: support of a separate entity. Obstet Gynecol. 1991;77:868–874.

    PubMed  CAS  Google Scholar 

  63. Schindler NR. Importance of the placenta and cord in the defense of neurologically impaired infant claims. Arch Pathol Lab Med. 1991;115:685–687.

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Pathology, British Columbia’s Children’s Hospital, 4480 Oak Street, V6H 3V4, Vancouver, B.C., Canada

    Virginia J. Baldwin M.D.

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  1. Virginia J. Baldwin M.D.
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© 1994 Springer-Verlag New York Inc

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Baldwin, V.J. (1994). The Placenta in Multiple Pregnancy. In: Pathology of Multiple Pregnancy. Springer, New York, NY. https://doi.org/10.1007/978-1-4613-9514-0_3

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  • DOI: https://doi.org/10.1007/978-1-4613-9514-0_3

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4613-9516-4

  • Online ISBN: 978-1-4613-9514-0

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