Skip to main content
SpringerLink
Log in

Aspects of Human Chronopathology

  • Conference paper
Biological Rhythms and Medicine

Part of the book series: Topics in Environmental Physiology and Medicine ((TEPHY))

Abstract

Often in an individual or a group of patients the manifestation of disease or the exacerbation of symptoms is predictable, exhibiting time dependencies (chronopathologies) over 24-hr, 1-month, and 1-year periods. Chronopathology may involve also alterations in the temporal structure of biological functions quantifiable by differences in the period, acrophase, mesor, and/or amplitude, preceding, following, or coincident with a change in health status. While the major emphasis of most investigations has been the substantiation of periodicities in the occurrence of symptoms or morbid events, the study of changes in the body’s temporal structure associated with the commencement of illness has yet to be vigorously pursued.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Abel, H (1931) Seasonal variations in weight of newborn. Z Kinderheilk 52: 31–40.

    Google Scholar 

  • Abels, H (1922) Über die Wichtigkeit der Vitamine für die Entwicklung des menschlichen fötalen und mütterlichen Organismus. Klin Wochenschr 1: 1785–1787.

    Google Scholar 

  • Adams, F (ed. and trans.) (1856) The Extant Works of Aretaeus, the Cappadocian. London: Printed for the Sydenham Society.

    Google Scholar 

  • Amir, M (1971) Patterns in Forcible Rape. Chicago: University of Chicago Press.

    Google Scholar 

  • Anonymous (1983) Asthma at night. Lancet 1: 220–222.

    Google Scholar 

  • Anonymous (1910) Discussion on duodenal ulcer. Clin J R Soc Med, pp. 378–384.

    Google Scholar 

  • Antonis, A, Bersohn, I, Plotkin, R, Easty, DL, and Lewis, HE (1965) The influence of seasonal variation, diet, and physical activity on serum lipids in young men in Antarctica. Am J Clin Nutr 16: 428–435.

    PubMed  CAS  Google Scholar 

  • Apgar, V (1953) A proposal for a new method of evaluation of the newborn infant. Curr Res Anesth Analg 32: 260–267.

    PubMed  CAS  Google Scholar 

  • Apgar, V (1966) The newborn (Apgar) scoring system. Pediatr Clin North Am 13 (3): 645–650.

    PubMed  CAS  Google Scholar 

  • Apgar, V, Holaday, DA, James, LS, and Weisbrot, IM (1958) Evaluation of the newborn infant-second report. JAMA 168 (15): 1985–1988.

    CAS  Google Scholar 

  • Arcangeli, P, Furian, R, and Milano, M (1960) La percezione del tatto e del dolore nelle varie fasi del ciclo menstruale. Rass Neurol Veg 14: 461–473.

    PubMed  CAS  Google Scholar 

  • Aschoff, J (1981) Annual rhythms in man. In: Aschoff, J (ed), Biological Rhythms, Handbook of Behavioral Neurobiology. New York: Plenum 4: 475–487.

    Google Scholar 

  • Assenmacher, IA, and Farrier, DS (1978) Environmental Endocrinology. Berlin: Springer-Verlag.

    Google Scholar 

  • Backstrom, T (1976) Epileptic seizures in women related to plasma estrogen and progesterone during the menstrual cycle. Acta Neurol Scand 54: 321–347.

    PubMed  CAS  Google Scholar 

  • Baier, H, and Rompel-Purckhauer, C (1979) Circadian variation of the effect of physical training. Chronobiologia 6: 77.

    Google Scholar 

  • Balaz, V (1970) Diurnal periodicity of dyspnea in bronchial asthma. Vnitr Lek 16: 1007–1016.

    PubMed  CAS  Google Scholar 

  • Barnes, P, Fitzgerald, G, Brown, M, and Dollery, C (1980) Nocturnal asthma and changes in circulating epinephrine, histamine, and cortisol. N Engl J Med 303: 263–267.

    PubMed  CAS  Google Scholar 

  • Barnes, PJ, Fitzgerald, GA, and Dollery, CT (1982) Circadian variation in adrenergic responses in asthmatic patients. Clin Sci 62: 349–354.

    PubMed  CAS  Google Scholar 

  • Bartter, FC, Delea, C, Baker, W, Halberg, F, and Lee, J-K (1976) Chronobiology in the diagnosis and treatment of mesor-hypertension. Chronobiologia 3: 199–213.

    PubMed  CAS  Google Scholar 

  • Bateman, JRM, and Clark, SW (1979) Sudden death in asthma. Thorax 34: 40–44.

    PubMed  CAS  Google Scholar 

  • Batschelet, E, Hillman, D, Smolensky, MH, and Halberg, F (1973) Angular-linear correlation coefficient for rhythmometry and circannually changing human birth rates at different geographic latitudes. Int J Chronobiol 1: 183–202.

    PubMed  CAS  Google Scholar 

  • Beau, M (1836) Recherches statistics pour servir à l’histoire de l’épilepsie et de l’hystérie. Arch Gen Med 11: 328–352.

    Google Scholar 

  • Benoit, J, and Assenmacher, I (1970) La photorégulation de la reproduction chez les oiseaux et les mammifères. Paris CNRS 172:1.

    Google Scholar 

  • Bivings, L (1934) Racial, geographic, annual and seasonal variations in birth weights. Am J Ob-stet Gynecol 27: 725–728.

    Google Scholar 

  • Bock, KD, and Kreuzenbeck, W (1966) Spontaneous blood-pressure variations in hypertension. The effect of antihypertensive therapy and correlations with the incidence of complications. In: Gross, F (ed), Ciba Symposium on Hypertensive Therapy, Principles, and Practices. New York: Springer-Verlag, pp. 224–241.

    Google Scholar 

  • Borelli, S, Chlebarov, S, and Flach, E (1966) Atopic neurodermatitis, and the problem of its 24-hour rhythm and its dependence on weather and climate. Munch Med Wochenschr 108: 474–480.

    PubMed  CAS  Google Scholar 

  • Bosse, K, and Ladebeck, HE (1972) Die kutane Histaminreaktion in Korrelation zum Cyclus der Frau. Z Haut Geschlechtskr 47: 365–370.

    PubMed  CAS  Google Scholar 

  • Bouvrain, Y, Coumel, P, and Leclercq, JF (1977) Arrhythmias and chronobiology. Arch Mal Coeur 70: 781–787.

    PubMed  CAS  Google Scholar 

  • Boyd, TAS, and McLeod, LE (1964) Circadian rhythms of plasma corticoid levels, intraocular pressure and aqueous outflow facility in normal and glaucomatous eyes. Ann NY Acad Sci 117: 597–613.

    PubMed  CAS  Google Scholar 

  • Boyd, TAS, McLeod, LE, Hassard, DTR, and Patrick, A (1962) Relation of diurnal variation of plasma corticoid levels and intraocular pressure in glaucoma. Can Med Assoc J 86: 772–775.

    PubMed  CAS  Google Scholar 

  • Bratescu, A, and Teodorescu, M (1981) Circannual variations in the B cell/T cell ratio in normal human peripheral blood. Allergy Clin Immunol 68 (4): 273–280.

    CAS  Google Scholar 

  • Breart, G, and Rumeau-Rouquette, C (1979) Rhythmes spontanés et rythmes induits dans le déclenchement et le déroulement du travail et de l’accouchement. J Interdiscipl Cycle Res 10: 195–205.

    Google Scholar 

  • Brennan, PJ, Greenberg, G, Miall, WE, and Thompson, SG (1982) Seasonal variation in 5: Human Chronopathology 197 arterial blood pressure. Br Med J 285: 919–922.

    CAS  Google Scholar 

  • Brisse, B, Bender, F, Gradaus, D, Gülker, H, Schwippe, G, Bramann, H, and Kuhs, H (1979) Circadian changes of heart rate and arrhythmias. Chronobiologia 6: 81.

    Google Scholar 

  • Brown, FM, and Graeber, RC (1982) Rhythmic Aspects of Behavior. Hillsdale, N.J.: Lawrence Erlbaum Assoc.

    Google Scholar 

  • Buek, HW (1829) Nachrichten von dem Gesundheitszustand der Stadt Hamburg. In: Ger-sons und Julius Magazin der Ausländischen Litterature der Gesammten. Hamburg: Heilkunde, pp. 347–354.

    Google Scholar 

  • Bunning, E (1963) Die Physiologische Uhr. Berlin: Springer-Verlag.

    Google Scholar 

  • Burge, PS, Edge, G, Hawkins, R, White, V, and Newman-Taylor, AJ (1981). Occupational asthma in a factory making flux-covered solder containing colophony. Thorax 36: 828–834.

    PubMed  CAS  Google Scholar 

  • Bury, JS (1902) Two cases of paralysis agitans in the same family in which improvement followed the administration of hyoscine. Lancet 1: 1097.

    Google Scholar 

  • Buzzelli, G, Procacci, P, Voegelin, MR, and Bozza, G (1968) Changes in the cutaneous pricking pain threshold during the menstrual cycle. Arch Fisiol 66: 97–106.

    Google Scholar 

  • Campbell, M (1962) Factors in the aetiology of pulmonary stenosis. Br Heart J 24: 625–632.

    PubMed  CAS  Google Scholar 

  • Carandente, F, Halberg, E, and Halberg, F (1978) Circadian periodicity and stomach ulcer. An animal experiment model for the detection of rhythm factors in the genesis of civilization diseases. Fortschr Med 96: 983–988.

    PubMed  CAS  Google Scholar 

  • Chiray, M, Mollard, H, and Duret, M (1940) Asthma and variation of ovarian hormone secretions. Presse Med 48: 201–203.

    Google Scholar 

  • Christ, JE, and Hoff, HE (1975) An analysis of the circadian rhythmicity of atrial and ventricular rates in complete heart block. J Electrocardiol 8: 69–72.

    PubMed  CAS  Google Scholar 

  • Churina, SK, Ganelina, IE, and Vol’Pert, EI (1975) Pattern of the incidence of acute myocardial infarct within a 24-hour period. Kardiologiia 15: 115–118.

    PubMed  CAS  Google Scholar 

  • Clark, TJH, and Hetzel, MR (1977) Diurnal vari- ation of asthma. Br J Dis Chest 71: 87–92.

    PubMed  CAS  Google Scholar 

  • Claude, F, and Allemany Vall, R (1938) Asthma and menstruation. Presse Med 46: 755–759.

    Google Scholar 

  • Cohen, P (1970) Seasonal variation of congenital malformations. J Interdiscipl Cycle Res 3: 271–274.

    CAS  Google Scholar 

  • Cohen, P (1971) Seasonal variations of congenital dislocation of the hip. J Interdiscipl Cycle Res 2: 417–425.

    Google Scholar 

  • Colquhoun, WP (1971) Biological Rhythms and Human Performance. London: Academic Press.

    Google Scholar 

  • Colquhoun, WP, Folkard, S, Knauth, P, and Rutenfranz, J (eds) (1975) Experimental Studies of Shiftwork. Opladen: Westdeutscher Verlag.

    Google Scholar 

  • Cormia, FE (1952) Experimental histamine pruritus. I. Influence of physical and psychological factors on threshold reactivity. J Invest Dermatol 19: 21–34.

    PubMed  CAS  Google Scholar 

  • Cowgill, UM (1966a) Historical study of the season of birth in the city of York, England. Nature 209: 1067–1070.

    CAS  Google Scholar 

  • Cowgill, UM (1966b) Season of birth in man. Contemporary situation with special reference to Europe and the southern hemisphere. Ecology 47: 614–623.

    Google Scholar 

  • Cowgill, UM (1966c) Season of birth in man: The northern new world. Kroeber Anthr Soc Pa 35: 1–9.

    Google Scholar 

  • Czeizel, E, and Elek, E (1967) Seasonal changes in the frequency of fetal damages and fertility. Gynaecologie 164: 89–95.

    CAS  Google Scholar 

  • Dalessio, DJ (1973) Hormonal levels linked to migraine during the menstrual period. Headache 13 (1): 29–31.

    PubMed  CAS  Google Scholar 

  • Dalton, KD (1964) The Premenstrual Syndrome. Springfield, Ill.: Thomas.

    Google Scholar 

  • Dalton, K (1967) Influence of menstruation on glaucoma. Br J Ophthalmol 51: 692–695.

    PubMed  CAS  Google Scholar 

  • Dalton, K (1973) Progesterone suppositories and pessaries in the treatment of menstrual migraine. Headache 12: 151–159.

    PubMed  CAS  Google Scholar 

  • Dalton, K (1976) Migraine and oral contraceptives. Headache 15: 247–251.

    PubMed  CAS  Google Scholar 

  • Dalton, KD (1977) The Premenstrual Syndrome and Progesterone Therapy. Chicago: Yearbook Medical.

    Google Scholar 

  • Davies, RJ, Green, M, and Schofield, NM (1976) Recurrent nocturnal asthma after exposure to grain dust. Am Rev Respir Dis 114: 1011–1019.

    PubMed  CAS  Google Scholar 

  • Davis, CTM, and Sargent, AJ (1975) Circadian variation in physiological responses to exercise on a stationary bicycle ergometer. Br J Industr Med 32: 110–114.

    Google Scholar 

  • Dawkins, KD, and Muers, MF (1981) Diurnal variation in airflow obstruction in chronic bronchitis. Thorax 36: 618–621.

    PubMed  CAS  Google Scholar 

  • Deininger, BR, and Rott, HD (1973) Cytogenetic studies on the seasonal variations in the rate of spontaneous chromosomal aberrations in man. Acta Genet Med Gemellol 22: 19–26.

    PubMed  CAS  Google Scholar 

  • Delbarre, F (1979) Chronobiology in the service of public health. In: Reinberg, A, and Halberg, F (eds), Chronopharmacology. Oxford: Pergamon Press, pp. 15–34.

    Google Scholar 

  • Dent, RR, Guilleminault, C, Albert, LH, Posner, BI, Cox, BM, and Goldstein, A (1981) Diurnal rhythm of plasma immunoreactive beta-endorphin and its relationship to sleep stages and plasma rhythms of cortisol and prolactin. J Clin Endocrinol Metab 52: 942–947.

    PubMed  CAS  Google Scholar 

  • DeRudder, B (1952) Der Grundriss einer Meteorobiologie des Menschen: Wetter und Jahreszeiteneinflüsse. Berlin: Springer-Verlag.

    Google Scholar 

  • Descovitch, GC, Montalbetti, N, Kuhl, JFW, Rimondi, S, Halberg, F and Ceredi, C (1974) Age and catecholamine rhythms. Chrono-biologia 1: 163–171.

    Google Scholar 

  • DeVries, K, Goei, JT, Booy-Noord, H, and Orie, NGM (1962) Changes during 24 hours in the lung function and histamine hyperreactivity of the bronchial tree in asthmatic and bronchitic patients. Int Arch Allerg Appl Immunol 20: 93–101.

    CAS  Google Scholar 

  • Dexter, JD, and Weitzman, ED (1970) The relationship of nocturnal headaches to sleep stage patterns. Neurology 20: 513–518.

    PubMed  CAS  Google Scholar 

  • Doyle, JT, Kinch, SH, and Brown, DF (1965) Seasonal variation in serum cholesterol concentration. J Chronic Dis 18: 657–664.

    CAS  Google Scholar 

  • Dubrasquet, M, Sergent, D, Lewin, M, and Bonfils, S (1971) Relationship between circadian rhythms, spontaneous activity, and restraint ulcer in the rat. In: Pfeiffer, CJ (ed), Peptic Ulcer. Copenhagen: Munkgaard, pp. 105–112.

    Google Scholar 

  • Duke-Elder, S (1952) The phasic variations in the ocular tension in primary glaucoma. Am J Ophthalmol 35: 1–21.

    PubMed  CAS  Google Scholar 

  • Edwards, JH (1961) Seasonal incidence of congenital disease in Birmingham. Ann Hum Genet 25: 89–93.

    PubMed  CAS  Google Scholar 

  • Ehret, CF, Groh, KR, and Meinert, JC (1978) Circadian dyschronism and chronotypic ecophilia as factors in aging and longevity. In: Samis, HV, and Capobianco, S (eds), Aging and Biological Rhythms. New York: Plenum Press, pp. 185–214.

    Google Scholar 

  • Ekbom, KA (1947) Ergotamine tartrate orally in Horton’s “histaminic cephalgia” (also called Harris’s “ciliary neuralgia”). Acta Psychiatr Neurol (Suppl) 46: 106–113.

    Google Scholar 

  • Ekbom, KA (1970) Patterns of cluster headache with a note on the relations to angina pectoris and peptic ulcer. Acta Neurol Scand 46: 225–237.

    PubMed  CAS  Google Scholar 

  • Eltringham, RJ, and Dobson, MB (1979) Cardiorespiratory arrests-a diurnal variation? Br J Anaesth 51: 72.

    PubMed  CAS  Google Scholar 

  • Engle, R, Halberg, F, and Gurly, R (1952) The diurnal rhythm in EEG discharge and in circulating eosinophils in certain types of epilepsy. Electroencephalogr Clin Neurophysiol 4: 115–116.

    Google Scholar 

  • Farah, FS, and Shbaklu, Z (1971) Autoimmune progesterone urticaria. J Allergy Clin Immunol 48: 257–261.

    PubMed  CAS  Google Scholar 

  • Farner, DS, and Wingfield, JC (1978) Environmental endocrinology and the control of annual reproductive cycles in passerine birds. In: Assenmacher, I, and Farner, DS (eds), Environmental Endocrinology. Berlin: Springer-Verlag, pp. 44–51.

    Google Scholar 

  • Feigin, GA, Fraser, RC, and Peterson, NS (1978) Sex hormones and the immune response. II. Perturbation of antibody production by estradiol 17B. Int Arch Allergy Appl Immunol 57: 488–497.

    Google Scholar 

  • Feigin, RD, Middelkamp, JN and Reed, C (1972) Circadian rhythmicity of mice to sublethal coxsackie B3 infection. Nature (New Biol) 240: 57–58.

    CAS  Google Scholar 

  • Feigin, RD, San Joaquin, VH, Hamond, MW, and Wyatt, RG (1969) Daily periodicity of susceptibility of mice to pneumococcal infection. Nature 224: 379–380.

    PubMed  CAS  Google Scholar 

  • Féré, C (1888) De la fréquence des accés d’épilepsie suivant les heures. CR Soc Biol 40: 740–742.

    Google Scholar 

  • Ferrario, VF, Bianchi, R, Giunta, G, and Roveda, L (1982) Circadian rhythm in human intraocular pressure. Chronobiologia 9: 33–38.

    PubMed  CAS  Google Scholar 

  • Feurle, G, Ketterer, H, Becker, HD, and Creutzfeldt, W (1972) Circadian serum gastrin concentrations in control persons and in patients with ulcer disease. Scand J Gastroenterol 7: 177–183.

    PubMed  CAS  Google Scholar 

  • Fine, PEM, and Clarkson, JA (1982) Measles in England and Wales-1: An analysis of factors underlying seasonal patterns. Int J Epidemiol 11: 5–25.

    PubMed  CAS  Google Scholar 

  • Folkard, S (1976) Diurnal variation and individual differences in the perception of intractable pain. J Psychosom Res 20: 289–301.

    PubMed  CAS  Google Scholar 

  • Fröland, A (1967) Seasonal dependence in birth of patients with Klinefelter’s syndrome. Lancet 2: 771.

    Google Scholar 

  • Fuller, CA, Lydic, R, Sulzman, FM, Albers, HE, Tepper, B, and Moore-Ede, MC (1981) Circadian rhythm of body temperature persists after suprachiasmatic lesions in the squirrel monkey. Am J Physiol 241: R385 - R391.

    PubMed  CAS  Google Scholar 

  • Fyfe, T, Dunnigan, MG, Hamilton, E, and Rae, RJ (1968) Seasonal variation in serum lipids, and incidence and mortality of ischaemic heart disease. J Atheroscler Res 8: 591–596.

    PubMed  CAS  Google Scholar 

  • Gandevia, B, and Milne, J (1970) Occupational asthma and rhinitis due to Western red cedar (Thuja plicata), with special reference to bronchial reactivity. Br J Ind Med 27: 235–244.

    PubMed  CAS  Google Scholar 

  • Gaultier, C, Reinberg, A, and Girard, F (1977) Circadian rhythms in lung resistance and dynamic lung compliance of healthy children. Effects of two bronchodilators. Resp. Physiol. 31: 169–182.

    CAS  Google Scholar 

  • Gautherie, M, and Gros, C (1977) Circadian rhythm alteration of skin temperature in breast cancer. Chronobiologia 4: 1–17.

    PubMed  CAS  Google Scholar 

  • Géber, H (1921) Einige Daten zur Pathologie der Urticaria menstruationalis. Dermatol Zochenschr 32: 143–150.

    Google Scholar 

  • Gervais, P, Reinberg, A, Gervais, C, Smolensky, MH, and DeFrance, O (1977) Twenty-four-hour rhythm in the bronchial hyperreactivity to house dust in asthmatics. J Allergy Clin Immunol 59: 207–213.

    PubMed  CAS  Google Scholar 

  • Géuber, J (1939) Densensitization in the treatment of menstrual intoxication and other allergic symptoms. Br J Dermatol 51: 265–268.

    Google Scholar 

  • Glynn, CJ, Lloyd, JW, and Folkard, S (1975) The diurnal variation in perception of pain. Proc R Soc Med 69: 369–372.

    Google Scholar 

  • Goodwin, F, and Wehr, T (eds) (1981) Circadian Rhythms in Psychiatry. California: Boxwood Press.

    Google Scholar 

  • Gowers, WR (1885) Epilepsy and Other Chronic Convulsive Diseases: Their Causes, Symptoms and Treatment. New York: William Wood & Co.

    Google Scholar 

  • Gowers, WR (1901) Epilepsy and Other Convulsive Diseases: Their Causes, Symptoms and Treatment, 2nd ed. Philadelphia: P. Blakeston’s Son and Co.

    Google Scholar 

  • Grabfield, GP, and Martin, EG (1913) Variations in the sensory threshold for faradic stimulation in normal human subjects. I. The diurnal rhythm. Am J Physiol 31: 300–308.

    Google Scholar 

  • Grammer, L, Levitz, D, Roberts, M, Pruzansky, JJ, and Zeiss, CR (1981) Seasonal variation of IgE antibody specific for ragweed antigen E ( IgE-a-AgE) from the basophil surface in patients with ragweed pollenosis. Int Arch Allergy Appl Immunol 66: 179–188.

    PubMed  CAS  Google Scholar 

  • Green, KG, Inman, WHW, and Thorp, JM (1963) Multicentre trial in the United Kingdom and Ireland of a mixture of ethyl chlorophenoxyisobutyrate and androsterone (Atromid). A preliminary report. J Atheroscler Res 3: 593–616.

    PubMed  CAS  Google Scholar 

  • Greene, R (1967) Menstrual headache. Res Clin Stud Headache 1: 62–73.

    Google Scholar 

  • Griffiths, GM, and Fox, JT (1938) Rhythm in epilepsy. Lancet 2: 409–416.

    Google Scholar 

  • Gulyuk, NG (1961) Seasonal and diurnal rhythms of labor in women. Relation of some complications in labor to the daily rhythm of labor activity. Akush Ginekol 37: 45–49.

    Google Scholar 

  • Guy, WH, Jacob, FM, and Guy, WB (1951) Sex hormone sensitization (corpus luteum). Arch Dermatol 63: 377–378.

    CAS  Google Scholar 

  • Gyârfâs, I, Csukas, A, Horvath-Gaucli, I (1976) Analysis of the diurnal periodicity of acute myocardial infarction attacks. Santé Publique (Bucur) 19: 77–84.

    Google Scholar 

  • Haberman, S, Capildeo, R, and Rose, FC (1981) The seasonal variation in mortality from cerebrovascular disease. J Neurol Sci 52: 25–36.

    PubMed  CAS  Google Scholar 

  • Halberg, E, Halberg, F, Cornelissen, G, Garcia-Sainz, M, Simpson, HW, Taggett-Anderson, MA, and Haus, E (1979) Toward a chronopsy: II. A thermopsy revealing asymmetrical circadian variation in surface temperature of human female breasts and related studies. Chronobiologia 6: 231–257.

    PubMed  CAS  Google Scholar 

  • Halberg, F (1953) Some physiological and clinical aspects of 24-hour periodicity. Lancet (Minneapolis) 73: 20–32.

    CAS  Google Scholar 

  • Halberg, F (1964) Organisms as circadian systems; temporal analysis of their physiologic and pathologic responses, including injury and death. In: Medical Aspects of Stress in the Military Climate. Walter Reed Army Institute of Research. Washington, D.C.: Walter Reed Army Medical Center, pp. 1–36.

    Google Scholar 

  • Halberg, F (1969) Chronobiology. Ann Rev Physiol 31: 675–725.

    CAS  Google Scholar 

  • Halberg, F, Gupta, BD, Haus, E, Halberg, E, Deka, AC, Nelson, W, Sothern, RB, Cornelissen, G, Klee, J, Lakatua, DJ, Scheving, LE, and Burns, ER (1977) Steps toward a cancer chronopolytherapy. In: 14th Therapeutic Int. Cong., Montpellier, 1977. Paris: Expansion Scientifique, pp. 151–196.

    Google Scholar 

  • Halberg, F, Haus, E, Ahlgren, A, Halberg, E, Strobel, H, Angellar, A, Kuhl, JFW, Lucas, R, Gedgaudas, E, and Leong, J (1974) Blood pressure self-measurements for computer health assessment and the teaching of chrono-biology in high schools. In: Scheving, LE, Halberg, F, and Pauly, JE (eds), Chrono-biology. Tokyo: Igaku Shoin, pp. 372–378.

    Google Scholar 

  • Halberg, F, and Howard, RB (1958) 24-hour periodicity and experimental medicine; examples and interpretations. Postgrad Med 24:349-358.

    PubMed  CAS  Google Scholar 

  • Halberg, F, Johnson, EA, Brown, BW, and Bittner, JJ (1960) Susceptibility rhythm to E. coli endotoxin and bioassay. Proc Soc Exp Biol Med 103: 142–144.

    PubMed  CAS  Google Scholar 

  • Halberg, F, Lagoguey, M, and Reinberg, A (1983) Human circannual rhythms over a broad spectrum of physiological processes. Int J Chronobiol (in press).

    Google Scholar 

  • Halberg, F, and Reinberg, A (1967) Rythmes circadiens et rythmes de basses fréquences en physiologie humaine. J Physiol (Paris) 59: 117–200.

    CAS  Google Scholar 

  • Halberg, F, Spink, WW, Albrecht, P, and Gully, RJ (1955) Resistance of mice to brucella somatic antigen, 24-hour periodicity and the adrenals. J Clin Endocrinol Metab 15: 887.

    Google Scholar 

  • Halberg, F, and Stephens, AN (1958) Twenty-four-hour periodicity in mortality of C-mice from E. coli lipopolysaccharide. Fed Proc 17: 439.

    Google Scholar 

  • Hall, SM (1977) Treatment of menstrual epilepsy with a progesterone-only oral contraceptive. Epilepsia 18: 235–236.

    PubMed  CAS  Google Scholar 

  • Hansen-Pruss, OC, and Raymond, R (1942) Skin reactivity during the menstrual cycle. J Clin Endocrinol Metab 2: 161–166.

    Google Scholar 

  • Hardvogl, M, and Stögmann, W (1976) Hereditäre progressive Dystonie mit Tagesschwankungen (abstract). Jahrestag Ost Ges Kinderheilkd Millstatt 24: 9.

    Google Scholar 

  • Harkness, JAL, Panayi, GS, Richter, MB, Van de Pette, K, Unger, A, and Pownall, R (1981) Circadian variation in disease activity in rheumatoid arthritis. Ann Rheum Dis 40: 529.

    Google Scholar 

  • Harkness, JAL, Richter, MB, Panayi, GS, Van de Pette, K, Unger, A, Pownall, R, and Geddawi, M (1982) Circadian variation in disease activity in rheumatoid arthritis. Br Med J 284: 551–554.

    CAS  Google Scholar 

  • Harris, W (1926) Neuritis and Neuralgia. London: Oxford University Press.

    Google Scholar 

  • Harris, W (1936) Ciliary (migrainous) neuralgia and its treatment. Br Med J 1: 457–460.

    PubMed  CAS  Google Scholar 

  • Haus, E, and Halberg, F (1970) Circannual rhythm in level and timing of serum corticosterone in standardized inbred mature C-mice. Environ Res 3: 81–106.

    PubMed  CAS  Google Scholar 

  • Haywood, TJ, and McGovern, JP (1968) So-called “nonspecific” factors in allergic disease. Ann Allergy 26: 299–304.

    PubMed  CAS  Google Scholar 

  • Hejl, Z (1977) Daily, lunar, yearly, and menstrual cycles and bacterial or viral infections in man. J Interdiscipl Cycle Res 8: 250–253.

    Google Scholar 

  • Henkind, P, and Walsh, JB (1981) Diurnal variations in intraocular pressure. Chronic open angle glaucoma. Preliminary report. Trans Ophthalmol Soc NZ 33: 18–20.

    CAS  Google Scholar 

  • Hetzel, MR, and Clark, TJH (1978) Clinical importance of circadian factors in severe asthma. In: Reinberg, A, and Halberg, F (eds), Chronopharmacology. Oxford: Perga-mon, pp. 213–221.

    Google Scholar 

  • Hetzel, MR, and Clark, TJH (1980) Comparison of normal and asthmatic circadian rhythms in peak expiratory flow rate. Thorax 35: 732–738.

    PubMed  CAS  Google Scholar 

  • Hetzel, MR, Clark, TJH, and Branthwaite, MA (1977a) Asthma: analysis of sudden deaths and ventilatory arrests in hospital. Br Med J 1: 808–811.

    PubMed  CAS  Google Scholar 

  • Hetzel, MR, Clark, TJH, and Houston, K (1977b) Physiological patterns in early morning asthma. Thorax 32: 418–423.

    PubMed  CAS  Google Scholar 

  • Hewitt, D (1962) A study of temporal variations in the risk of fetal malformation and death. Am J Public Health 52: 1676–1688.

    CAS  Google Scholar 

  • Hildebrandt, G (1962) Biologische Rhythmen und ihre Bedeutung fur die Bäder-und Klimaheilkunde. In: Amelung, W, and Evers, A (eds), Handbuch der Bäder-und Klimaheilkunde. Stuttgart: Schattauer-Verlag, pp. 730–785.

    Google Scholar 

  • Hildebrandt, G, Rohmert, W, and Rutenfranz, J (1973) Über Jahresrhythmische Häufigkeitsschwankungen der Inanspruchnahme von Sicherheitseinrichtungen durch die Triefbfahrzeugführer der Deutschen Bundesbahn. Int Arch Arbeitsmed 31: 73–80.

    PubMed  CAS  Google Scholar 

  • Hopkins, H (1933) The time of appearance of epileptic seizures in relation to age, duration and type of the syndrome. J Nerv Ment Dis 77: 153–162.

    Google Scholar 

  • Hoseason, AS (1938) Vasomotor rhinorrhoea with asthma, associated with menstruation. Br Med J 2: 703–704.

    PubMed  CAS  Google Scholar 

  • Hrdlicka, J, Krutova, K, and Malek, J (1950) Frequency of premature deliveries according to weight and length of fetuses and their seasonal rhythm. Cs Gynec 29: 26–34.

    Google Scholar 

  • Hughes, E (1931) Seasonal Variation in Man. London: Lewis.

    Google Scholar 

  • Hunt, JR (1917) Progressive atrophy of the globus pallidus (primary atrophy of the pallidal system). Brain 40: 58–148.

    Google Scholar 

  • Huntington, E (1938) Season of Birth; Its Relation to Human Abilities. New York: Wiley.

    Google Scholar 

  • Hutchison, R, and Moynihan, BGA (1909) Hunger pain and duodenal ulcer. Br Med J 1: 926–927.

    Google Scholar 

  • Illingworth, CFW, Scott, LDW, and Jamieson, RA (1944a) Acute perforated peptic ulcer. Frequency and incidence in the west of Scotland. Br Med J 2: 655–658.

    Google Scholar 

  • Illingworth, CFW, Scott LDW, and Jamieson, RA (1944b) Acute perforated peptic ulcer. Frequency and incidence in the west of Scotland. Br Med J 2: 617–620.

    Google Scholar 

  • Ilmarinen, J, Rutenfranz, J, Kylian, H, and Klimt, F (1975) Untersuchungen zur Tagesperiodik verschiedener Kreislauf-und Atemgrößen bei submaximalen und maximalen Leistungen am Fahrradergometer. Europ J Appl Physiol 34: 255–267.

    CAS  Google Scholar 

  • Islam, MS (1981) Seasonal rhythm of airway resistance and intrathoracic gas volume in healthy females and males. Respiration 42: 193–199.

    PubMed  CAS  Google Scholar 

  • Job, C, Reinberg, A, and Delbarre, F (1981) Chronoeffectiveness of indomethacin in four patients suffering from an evolutive coxarthrosis or gonarthrosis. Int J Chronobiol 7: 65.

    Google Scholar 

  • Johnasson, BW (1972) Myocardial infarction in Malmö-1960–1968. Acta Med Scand 191: 505–515.

    Google Scholar 

  • Johnson, LC, Tepas, DI, Colquhoun, WP, and Colligan, MJ (1981) Biological Rhythms, Sleep and Shift Work. New York: SP Medical and Scientific Books.

    Google Scholar 

  • Jongbloet, PH (1970) Chromosomal aberrations and month of birth. Lancet 2: 1317–1318.

    PubMed  CAS  Google Scholar 

  • Jongbloet, PH (1971) Month of birth and gametopathy. An investigation into patients with Down’s, Klinefelter’s and Turner’s syndrome. Clin Genet 2: 315–330.

    PubMed  CAS  Google Scholar 

  • Jares, A, and Frees, J (1937) Die Tageschwankungen der Schmerzempfindung. Dtsch Med Worchenschr 63: 962–963.

    Google Scholar 

  • Kales, A, Beall, GN, Bajor, GF, Jacobson, A, and Kales, JD (1968) Sleep studies in asthmatic adults: relationship of attacks to sleep stage and time of night. J Allergy 41: 164–173.

    PubMed  CAS  Google Scholar 

  • Kalter, H (1959) Seasonal variation in frequency of cortisone-induced cleft palate in mice. Genetics 44: 518–519.

    Google Scholar 

  • Kamraj-Mazurkiewicz, K (1971) Significance of the diurnal pattern in epileptic seizures in children. Neurol Neurochir Pol 5: 197–204.

    PubMed  CAS  Google Scholar 

  • Kashiwagi, T, McClure, JN Jr, and Wetzel, RD (1972) The menstrual cycle and headache type. Headache 12: 103–104.

    PubMed  CAS  Google Scholar 

  • Katavisto, M (1965) The diurnal variations of ocular tension in glaucoma. Acta Ophthalmol (Suppl) 78: 1–131.

    Google Scholar 

  • Katz, G (1953) Seasonal variation in incidence of premature births. Nord Med 50: 1637–1638.

    Google Scholar 

  • Kaufmann, MW, Gottlieb, G, Kahaner, K, Peselow, E, Stanley, M, Casadonte, P, and Deutsch, S (1981) Circadian rhythm and myocardial infarct: a preliminary study. IRCS Med Sci (Biochem) 9: 557.

    Google Scholar 

  • Kendell, RE, and Marshall, J (1963) Role of hypotension in the genesis of transient focal cerebral ischaemic attacks. Br Med J 2: 344–348.

    PubMed  CAS  Google Scholar 

  • Klein, KE, Brüner, H, Voigt, ED, and Wegmann, HM (1966) Comparative studies on physiological indices of fitness in man under exercise, low pressure and acceleration. In: Yoshimura, H, and Weiner, JS (eds), Human Adaptability and Its Methodology. Tokyo: Jpn. Soc. Promot. Sci., pp. 234–247.

    Google Scholar 

  • Klein, KE, and Wegmann, HM (1980) Significance of circadian rhythms in aerospace operations. In: Sleep, Wakefulness and Circadian Rhythms. NATO, AGARD Lecture Series 105, pp 2–1–2–17.

    Google Scholar 

  • Kleitman, N, and Ramsaroop, A (1946) Body temperature and cutaneous sensitivity to tingling and pain. Fed Proc 5: 56.

    PubMed  CAS  Google Scholar 

  • Kluger, MJ (1979) Fever: Its Biology, Evolution and Function. Princeton: Princeton University Press.

    Google Scholar 

  • Kovar, WR, and Taylor, RJ (1960) Is spontaneous abortion a seasonal problem? Obstet Gynecol 16: 350–353.

    PubMed  CAS  Google Scholar 

  • Kowanko, IC, Knapp, MS, Pownall, R, and Swannell, AJ (1982a) Domiciliary self-measurement in rheumatoid arthritis and the demonstration of circadian rhythmicity. Ann Rheum Dis 41: 453–455.

    PubMed  CAS  Google Scholar 

  • Kowanko, IC, Pownall, R, Knapp, MS, Swannell, AJ, and Mahoney, PGC (1982b) The time of day of prednisolone administration in rheumatoid arthritis. Ann Rheum Dis 41: 447–452.

    PubMed  CAS  Google Scholar 

  • Kowanko, IC, Pownall, R, Knapp, MS, Swannell, AJ, and Mahoney, PGC (1981) Circadian variations in the signs and symptoms of rheumatoid arthritis and in the therapeutic effectiveness of flurbiprofen at different times of the day. Br J Clin Pharmacol 11: 477–484.

    PubMed  CAS  Google Scholar 

  • Krieger, DT (ed) (1979) Endocrine Rhythms. New York: Raven Press.

    Google Scholar 

  • Kripke, DF, Mullaney, DJ, Atkinson, M, and Wolf, S (1978) Circadian rhythm disorders in manic-depressives. Biol. Psychiatry 13: 335–351.

    PubMed  CAS  Google Scholar 

  • Kripke, DF (1981) Phase advance theories for affective illnesses. In: Goodwin, F, and Wehr, T (eds), Circadian Rhythms in Psychiatry: Basic and Clinical Studies. California: Boxwood Press.

    Google Scholar 

  • Kronauer, RE, Czeisler, CA, Pilato, SF, Moore-Ede, MC, and Weitzman, ED (1982) Mathematical model of the human circadian system with two interacting oscillators. Am J Physiol 242: R3 - R17.

    PubMed  CAS  Google Scholar 

  • Kunkle, EC (1964) Time patterns in headache; their diagnostic and therapeutic significance. J Maine Med Assoc 55: 77–82.

    PubMed  CAS  Google Scholar 

  • Kunkle, EC, Pfeiffer, JB Jr, Wilhoit, WM, and Hamrick, LW Jr (1952) Recurrent brief headache in “cluster” pattern. Trans Am Neurol Assoc 77: 240–243.

    Google Scholar 

  • Kuroiwa, A (1978) Symptomatology of variant angina. Jpn Circ J 42: 459–476.

    Google Scholar 

  • Lagoguey, M, and Reinberg, A (1981) Circadian and circannual changes of pituitary and other hormones in healthy human males: their relationship with gonadal activity. In: Van Cauter, E, and Copinschi, G (eds), Human Pituitary Hormones. The Hague: Martinus Nijhoff, pp. 261–278.

    Google Scholar 

  • Laidlaw, J (1956) Catamenial epilepsy. Lancet 2: 1235–1237.

    Google Scholar 

  • Langdon-Down, M, and Brain, WR (1929) Time of day in relation to convulsions in epilepsy. Lancet 1: 1029–1032.

    Google Scholar 

  • Langley, D, and Swanljung, H (1951) Ocular tension in glaucoma simplex. Br J Ophthalmol 35: 445–458.

    PubMed  CAS  Google Scholar 

  • Lee, RE, Smolensky, MH, Leach, CS, and McGovern, JP (1977) Circadian rhythms in the cutaneous reactivity to histamine and selected antigens, including phase relationship to urinary cortisol excretion. Ann Allergy 38: 231–236.

    PubMed  CAS  Google Scholar 

  • Leech, SH, and Kumar, P (1981) Cyclic urti-caria. Ann Allergy 46: 201–203.

    PubMed  CAS  Google Scholar 

  • Leffingwell, A (1982) Illegitimacy and the Influence of Seasons upon Conduct; Two Studies in Demography. London: Sonnenschein and Co.

    Google Scholar 

  • Levine, H, Halberg, F, Hillman, DC, Fanning, R, Cornelissen, G, and DePrins, J (1979) Alteration of circadian core temperature rhythm characteristics and values outside habitual idiochronodesm as a result of laryngitis and transmeridian flight. Chronobiologia 6: 127–128.

    Google Scholar 

  • Li, TA (1936) Seasonal variation of the birth weight of the newborn. J Pediatr 8: 459–469.

    Google Scholar 

  • Lu, MC, Smolensky, MH, Hsi, B, and McGovern, JP (1980a) Seasonal changes in immunoglobulin and complement levels in atopic and non-atopic persons. In: Smolensky, MH, Reinberg, A, and McGovern, JP (eds), Recent Advances in the Chronobiology of Allergy and Immunology. Oxford: Perga-mon Press, pp. 261–273.

    Google Scholar 

  • Lu, MC, Smolensky, MH, Hsi, B, and McGovern, JP (1980b) Seasonal variation in total and specific IgE. In: Smolensky, MH, Reinberg, A, and McGovern, JP (eds), Recent Advances in the Chronobiology of Allergy and Immunology. Oxford: Pergamon Press, pp. 275–285.

    Google Scholar 

  • MacFarland, A (1978) Variations in number of births and perinatal mortality by day of week in England and Wales. Br Med J 2: 1670–1673.

    Google Scholar 

  • Magnussen, G (1936) 18 cases of epilepsy with fits in relation to sleep. Acta Psychiatr Neurol 11:289–321.

    Google Scholar 

  • Manery, JF (1979) Ions and body temperature. In: Lomax, P, and Schönbaum, E (eds), Body Temperature. Regulation, Drug Effects, and Therapeutic Implications. New York: Marcel Dekker, pp. 119–150.

    Google Scholar 

  • Mansfield, CM, Carabasi, RA, Wells, W, and Borman, K (1973) Circadian rhythm in the skin temperature of normal and cancerous breasts. Int J Chronobiól 1: 235–243.

    PubMed  CAS  Google Scholar 

  • Mansfield, CM, Wallace, JD, Curley, RF, Kramer, S, Southard, ME, and Driscoll, D (1970) A comparison of the temperature curves recorded over normal and abnormal breasts. Radiology 94: 697–698.

    PubMed  CAS  Google Scholar 

  • Marshall, J (1977) Diurnal variation in occurrence of strokes. Stroke 8: 230–231.

    PubMed  CAS  Google Scholar 

  • Martin, EG, Bigelow, GH, and Wilbur, GB (1914) Variations in the sensory threshold for faradic stimulation in normal human subjects. II. The nocturnal variation. Am J Physiol 33: 415–422.

    Google Scholar 

  • Master, AM (1960) The role of effort and occupation (including physicians) in coronary occlusion. JAMA 174: 942–948.

    PubMed  CAS  Google Scholar 

  • Master, AM, Dack, S, and Jaffe, HL (1937) Factors and events associated with onset of coronary artery thrombosus. JAMA 109: 546–549.

    Google Scholar 

  • Master, AM, and Jaffee, HL (1952) Factors in the onset of coronary occlusion and coronary insufficiency. JAMA 148: 794–798.

    CAS  Google Scholar 

  • McGovern, JP, Smolensky, MH, and Reinberg, A (1977a) Circadian and circamensual rhythmicity in cutaneous reactivity to histamine and allergenic extracts. In: McGovern, JP, Smolensky, MH, and Reinberg, A (eds), Chronobiology in Allergy and Immunology. Springfield: Thomas, pp. 79–116.

    Google Scholar 

  • McGovern, JP, Smolensky, MH, and Reinberg, A (1977b) Chronobiology in Allergy and Immunology. Springfield: Thomas.

    Google Scholar 

  • McKeown, T, and Record, RG (1951) Seasonal incidence of congenital malformations of the central nervous system. Lancet 1: 192–196.

    PubMed  CAS  Google Scholar 

  • Meyers, A, and Dewar, HA (1975) Circumstances attending 100 sudden deaths from coronary artery disease with coroners’ necropsies. Br Heart J 37: 1133–1143.

    Google Scholar 

  • Miettiner, OS, Reiner, ML, and Nadas, AS (1970) Seasonal incidence of coarctation of the aorta. Br Heart J 32: 103–107.

    Google Scholar 

  • Milne, J, and Gandevia, B (1969) Occupational asthma and rhinitis due to Western (Canadian) red cedar (Thuja plicata). Med J Aust 2: 741–744.

    PubMed  CAS  Google Scholar 

  • Mitchell, C (1970) Occupational asthma due to Western or Canadian red cedar (Thuja plicata). Med J Aust 2: 233–235.

    PubMed  CAS  Google Scholar 

  • Moore, JG, and Englert, E Jr (1970) Circadian rhythm of gastric acid secretions in man. Nature 226: 1261–1262.

    PubMed  CAS  Google Scholar 

  • Moore-Ede, MC, Sulzman, FM, and Fuller, CA (1982) The Clocks that Time Us. Cambridge: Harvard University Press.

    Google Scholar 

  • Moynihan, BGA (1910a) Duodenal Ulcer. Philadelphia: Saunders, pp. 101–121.

    Google Scholar 

  • Moynihan, BGA (1910b) Some remarks on dyspepsia. Dublin J Med Sci 130 (no. 463, 3rd series): 1–15.

    Google Scholar 

  • Murray, AB, Ferguson, AC, and Morrison, B (1980) The seasonal variation of allergic respiratory symptoms induced by house dust mites. Ann Allergy 45: 347–350.

    PubMed  CAS  Google Scholar 

  • Murray, AB, Ferguson, AC, and Morrison, B (1980) The seasonal variation of allergic respiratory symptoms induced by house dust mites. Ann Allergy 45: 347–350.

    PubMed  CAS  Google Scholar 

  • Nasu, H, Aoyama, T, and Morisada, A (1958) Four cases of juvenile paralysis agitans in a family Psychiatr. Neurol Jpn 60: 178–183.

    Google Scholar 

  • Neffen, H, Oehling, A, and Sanz, M-L (1980) Variations of the circadian rhythm in cAMP in bronchial asthma after administration of fenoterol. Allerg Immunopathol 8: 545–552.

    CAS  Google Scholar 

  • Newell, FW, and Krill, AE (1965) Diurnal tonography in normal and glaucomatous eyes. Am J Ophthalmol 59: 840–853.

    PubMed  CAS  Google Scholar 

  • Newmark, ME, and Penry, JK (1980) Catamenial epilepsy: a review. Epilepsia 21: 281–300.

    PubMed  CAS  Google Scholar 

  • Nicholson, PA, and Bogie, W (1973) Diurnal variation in the symptoms of hay fever: implications for pharmaceutical development. Curr Med Res Opin 1: 395–400.

    PubMed  CAS  Google Scholar 

  • Nielsen, J, and Friedrich, U (1969) Seasonal variation in non-disjunction of sex chromosomes. Humangenetik 8: 258–260.

    PubMed  CAS  Google Scholar 

  • Nielson, J, Peterson, GB, and Therkelsen, AJ (1973) Seasonal-variation in birth of children with aneuploid chromosome abnormalities-Report from Danish Cytogenetic Central Register. Hum Genet 19: 67–74.

    Google Scholar 

  • Nowlin, JB, Troyer, WG, Collins, WS, Silverman, G, Nichols, CR, McIntosh, HD, Estes, EH, and Bogdonoff, MD (1965) The association of nocturnal angina pectoris with dreaming. Ann Intern Med 63: 1040–1046.

    PubMed  CAS  Google Scholar 

  • O’Brien, IM, Harries, MG, Burge, PS, and Pepys, J (1979) Toluene diisocyanate induced asthma. 1. Reactions to TDI, MDI, HDI and histamine. Clin Allergy 9: 1–6.

    PubMed  Google Scholar 

  • Orie, NGM, Sluitter, HF, Tammeling, GJ, DeVries, K, and Wal, AMVD (1964). Fight against bronchitis. In: Orie, HGM, and Sluiter, NJ (eds), Bronchitis: 2nd International Bronchitis Symposium. Springfield IL: Thomas, pp. 352–369.

    Google Scholar 

  • Ortavant, R, and Reinberg, A (1980) Rythmes et Reproduction. Paris: Masson.

    Google Scholar 

  • Osterman, PO, Lovstrand, KG, Lundberg, PO, Lundquist, S, and Muhr, C (1981) Weekly headache periodicity and the effect of weather changes on headache. Int J Biometeorol 25: 39–45.

    PubMed  CAS  Google Scholar 

  • Osterman, PO, Lundberg, PO, Lundquist, S, Lovstrand, KG, and Muhr, C (1980) Weekly periodicity of headache and the effect of changes in weather on headache. Ups J Med Sci (Suppl) 31: 23–26.

    CAS  Google Scholar 

  • Ostfeld, AM (1963) The natural history and epidemiology of migraine and muscle contraction headache. Neurology 13: 11–15.

    Google Scholar 

  • Otto, W (1960) Jahreszeitliche Verteilung von Lebendgeborenen, Frühgeborenen, Totgeborenen and Gestorborenen. Artzl Forsch 14: 404–411.

    CAS  Google Scholar 

  • Ouvrier, RA (1978) Progressive dystonia with marked diurnal fluctuation. Ann Neurol 4: 412–417.

    PubMed  CAS  Google Scholar 

  • Ozkaragoz, K, and Cakin, F (1970) The effect of menstruation on immediate skin reactions in patients with respiratory allergy. J Asthma Res 7: 171–175.

    PubMed  CAS  Google Scholar 

  • Paloheimo, J (1961) Seasonal variations of serum lipids in healthy men. Ann Med Exp Biol. Fenn 39 (Suppl 8) pp. 1–88.

    PubMed  Google Scholar 

  • Parkes, AS (1968) Seasonal variation in human sexual activity. In: Thoday, JM and Parkes, AS (eds) Genetic and environmental influences on behavior; Eugenics Soc Symposium 4: 128–145.

    Google Scholar 

  • Patry, FL (1931) The relation of time of day, sleep and other factors to the incidence of epileptic seizures. Am J Psychiatr 87: 789–813.

    Google Scholar 

  • Pell, S, and D’Alonzo, CA (1963) Acute myocardial infarction in a large industrial population. JAMA 185: 831–838.

    PubMed  CAS  Google Scholar 

  • Pengelley, ET (ed) (1974) Circannual Clocks: Annual Biological Rhythms. New York: Academic Press.

    Google Scholar 

  • Pepys, J (1977) Clinical and therapeutic significance of patterns of allergic reactions of the lungs to extrinsic agents. Am Rev Resp Dis 116: 573–587.

    PubMed  CAS  Google Scholar 

  • Pepys, J, and Davies, RJ (1978) Occupational asthma. In: Middleton, E, Reed, CE, and Ellis EF (eds), Allergy, Principles and Practice. New York: Mosby, p. 812–842.

    Google Scholar 

  • Pepys, J, and Hutchcroft, BJ (1975) Bronchial provocation tests in etiologic diagnosis and analysis of asthma. Am Rev Resp Dis 112: 829–859.

    PubMed  CAS  Google Scholar 

  • Piazzini, M, Guaxxelli, R, Montali, E, Conti, C, and Bigozzi, U (1981) On the epidemiology of certain auxopathological conditions caused by numerical chromosomal aberrations: an investigation into the possibility of seasonal variations. Acta Med Auxol 13: 185–192.

    Google Scholar 

  • Pickering, G (1972) Hypertension: definitions, natural histories and consequences. Am J Med 52: 570–583.

    PubMed  CAS  Google Scholar 

  • Pickering, TG, Harshfield, GA, Kleinert, HD, Blank, S, and Laragh, JH (1982) Blood pressure during normal daily activities, sleep and exercise. JAMA 247: 992–996.

    PubMed  CAS  Google Scholar 

  • Pinatel, MC, Czyba, JC, and Souchier C (1982) Seasonal-changes in sexual hormones secretion, sexual-behavior and sperm production in man. Int J Andr Suppl 5: 183–190.

    CAS  Google Scholar 

  • Pinatel, MC, Souchier, C, Croze, JP, and Czyba, JC (1981) Seasonal variation of necrospermia in man. J Interdiscipl Cycle Res 12: 225–235.

    Google Scholar 

  • Pittendrigh, CS (1960) Circadian rhythms and the circadian organization of living systems. Cold Spring Harbor Symp Quant Biol 25: 159–184.

    PubMed  CAS  Google Scholar 

  • Polani, PE, and Campbell, M (1960) Factors in the causation of persistent ductus arteriosus. Ann Hum Genet 24: 343–357.

    PubMed  CAS  Google Scholar 

  • Pöllmann, L (1982) Uber tagesrhythmische Unterschiede der Wirkungsdauer eines Lokalanästhetikums. Dtsch Zahnärztl Z 37: 388–390.

    PubMed  Google Scholar 

  • Pöllmann, L, and Harris, PHP (1978) Rhythmic changes in pain sensitivity in teeth. Int J Chronobiol 5: 459–464.

    PubMed  Google Scholar 

  • Pöllmann, L, and Hildebrandt, G (1979) Circadian variations of potency of placebos on pain threshold in healthy teeth. Chronobiologia 6: 145.

    Google Scholar 

  • Pöllmann, L, and Hildebrandt, G (1979) Circadian variations of potency of placebos on pain threshold in healthy teeth. Chronobiologia 6: 145.

    Google Scholar 

  • Prevost, RJ, Smolensky, MH, Reinberg, A, Raymer, WJ, and McGovern, JP (1980) Circadian rhythm of respiratory distress in asthmatic, bronchitic and emphysemic patients. In: Smolensky, MH, Reinberg, A, and McGovern, JP (eds), Recent Advances in the Chronobiology of Allergy and Immunology. Oxford: Pergamon Press, pp. 237–250.

    Google Scholar 

  • Prinzmetal, M, Kennamer, R, Merliss, R, Wada, T, and Bor, N (1959) Angina pectoris. I. A variant form of angina pectoris. Am J Med 27: 375–388.

    PubMed  CAS  Google Scholar 

  • Proccacci, P, Buzzelli, G, Passeri, I, Sassi, R, Voegelin, MR, and Zoppi, M (1972) Studies on the cutaneous pricking pain threshold in man. Circadian and circatrigintan changes. Res Clin Stud Headache 3: 260–276.

    Google Scholar 

  • Proccacci, P, Corte MD, Zoppi, M, and Maresca, M (1974) Rhythmic changes of the cutaneous pain threshold in man. A general review. Chronobiologia 1: 77–96.

    Google Scholar 

  • Puchelle, E, Da Costa De Moraes, R, and Zahm, JM (1975) Variations diurnes da la visco-elasticite des secretions bronchiques chez le bronchitique chronique. Biorheology 12: 67–71.

    PubMed  CAS  Google Scholar 

  • Puscass, I, Turi, Z, and Chiu, A (1979) Critical consideration on the diagnostic value of nocturnal gastric secretion in duodenal ulcer patients. Rev Med Intern 31: 445–446.

    Google Scholar 

  • Quetelet, MA (1842) A treatise on man and the development of his faculties (R Knox, translator.) In: Chambers, W, and Chambers, R (eds), Chamber’s Information for the People. Edinburgh: W and R Chambers.

    Google Scholar 

  • Ramirez-Lassepas, M, Haus, E, and Lakatua, DJ (1978) Seasonal and circadian periodicity of spontaneous intracerebral hemorrhage. Proc. American Heart Association, 3rd International Joint Meeting on Stroke and Cerebral Circulation, Feb. 16–18, New Orleans, Louisiana.

    Google Scholar 

  • Ramirez-Lassepas, M, Haus, E, Lakatua, DJ, Sackett, L, and Swoyer, J (1980) Seasonal (circannual) periodicity of spontaneous intra-cerebral hemorrhage in Minnesota. Ann Neurol 8: 539–541.

    PubMed  CAS  Google Scholar 

  • Record, RG (1961) Anencephalus in Scotland. Br J Prey Soc Med 15: 93–105.

    CAS  Google Scholar 

  • Reinberg, A (1968) The hours of changing responsiveness or susceptibility. Perspect Biol Med 11: 111–128.

    Google Scholar 

  • Reinberg, A (1973) Biological rhythms and human biometeorology. Int J Biometeorol (Suppl) 16: 97–112.

    Google Scholar 

  • Reinberg, A (1979a) Circadian and circannual rhythms in healthy adults: sleep, wakefulness and circadian rhythm. In: Sleep, Wakefulness and Circadian Rhythms. NATO AGARD Lecture Series. 105 pp. 1–1–1–27.

    Google Scholar 

  • Reinberg, A (1979a) Circadian and circannual rhythms in healthy adults: sleep, wakefulness and circadian rhythm. In: Sleep, Wakefulness and Circadian Rhythms. NATO AGARD Lecture Series. 105 pp. 1–1–1–27.

    Google Scholar 

  • Reinberg, A (1980) La chronobiologie humaine (buts et definitions). In: Ortavant, R, and Reinberg, A (eds), Rhythmes et Reproduction. Paris: Masson, pp. 1–14.

    Google Scholar 

  • Reinberg, A (1982) Human chronobiology and adaptation. In: Hildebrandt, G, and Hensel, H (eds), Biological Adaptation. Stuttgart: Thieme Verlag, pp. 64–67.

    Google Scholar 

  • Reinberg, A, Gervais, P, Halberg, F, Gaultier, M, Roynette, N, Abulker, C, and Dupont, J (1973) Mortalité des adultes: rythmes circadiens et circannuels dans un hôpital parisien et en France. Nouv Presse Med 2: 289–294.

    PubMed  CAS  Google Scholar 

  • Reinberg, A, Gervais, P, Morin, M, and Abulker, C (1971a) Rhythme circadian humain du seuil de la réponse bronchique a l’acétylcholine. CR Acad Sci 272: 118, 791–881.

    Google Scholar 

  • Reinberg, A, Ghata, J, and Sidi, E (1963) Nocturnal asthma attacks: their relationship to the circadian adrenal cycle. J Allergy 34: 323–330.

    PubMed  CAS  Google Scholar 

  • Reinberg, A, Guillet, P, Gervais, P, Ghata, J, Vignaud, D, and Abulker, C (1977) One month chronocorticotherapy (Dutimelan, 815 mite). Control of the asthmatic condition without adrenal suppression and circadian rhythm alteration. Chronobiologia 4: 295–312.

    PubMed  CAS  Google Scholar 

  • Reinberg, A, and Lagoguey, M (1978a) Annual endocrine rhythms in healthy young adult men: their implication in human biology and medicine. In: Assenmacher, I, and Farner, DS (eds), Environmental Endocrinology. Berlin: Springer-Verlag, pp. 113–121.

    Google Scholar 

  • Reinberg, A, and Lagoguey, M (1978b) Circadian and circannual rhythms in sexual activity and plasma hormones (FSH, LH, testosterone) of five human males. Arch Sex Behav 7: 13–30.

    PubMed  CAS  Google Scholar 

  • Reinberg, A, Lagoguey, M, Chauffournier, JM, and Cesselin, F (1975) Circannual and circadian rhythms in plasma testosterone in five healthy young Parisian males. Acta Endocrinol (Kbh) 80: 732–743.

    CAS  Google Scholar 

  • Reinberg, A, Schuller, E, Clench, J, and Smolensky, MH (1980) Circadian and circannual rhythms of leukocytes, proteins, and immunoglobulins. In: Smolensky, MH, Reinberg, A, and McGovern, JP (eds), Recent Advances in the Chronobiology of Allergy and Immunology. Oxford: Pergamon Press, pp. 251–259.

    Google Scholar 

  • Reinberg, A, Schuller, E, Dlasnerie, N, Clench, J, and Helary, M (1971b) Rhythmes circadiens et circannuels des leucocytes, protéines totales, IgA, IgM, IgG d’adultes et sains. Nouv Presse Med 6: 3819–3823.

    Google Scholar 

  • Reinberg, A, and Smolensky, MH (1974) Circatrigintan secondary rhythms related to hormonal changes in the menstrual cycle. General considerations. In: Ferin, M, Halberg, F, Richart, RM, and Vande Wiele, RL (eds), Biorhythms and Human Reproduction. New York: Wiley, pp. 241–258.

    Google Scholar 

  • Reinberg, A, Smolensky, MH, Ghata, J, Gervais, A, and Gervais, P (1974) Approche chronobiologique des rhythmes mensuels des femms saines spontanément réglées. Ann Endocrinol 35: 309–310.

    CAS  Google Scholar 

  • Reinberg, A, Vieux, N, and Andlauer, P (eds) (1981) Night and Shift Work: Biological and Social Aspects. Oxford: Pergamon Press.

    Google Scholar 

  • Rippey, RM (1981) Overview: seasonal varia- tions in cholesterol. Prey Med 10: 655–659.

    CAS  Google Scholar 

  • Rogers, EJ, and Vilkin, B (1978) Diurnal variation in sensory and pain thresholds correlated with mood states. J Clin Psychiatry 39: 431–438.

    PubMed  CAS  Google Scholar 

  • Rosenberg, LA, and Heinonen, OP (1974) Seasonal occurrence of ventricular septal defect. Lancet 2: 903–904.

    PubMed  CAS  Google Scholar 

  • Rosenblatt, LS, Shifrine, M, Hetherington, NW, Paglieroni, T, and MacKenzie, MR (1982) A circannual rhythm in rubella antibody titers. J Interdiscipl Cycle Res 13: 81–88.

    Google Scholar 

  • Rossolini, A, and Chieffi, O (1964) On relationships between asthma and sex hormones in the woman. Atti Accad Fisiocrit Siena Medicofis 13: 231–247.

    CAS  Google Scholar 

  • Rothman, KJ, and Fyler, DC (1974) Seasonal occurrence of complex ventricular septal defect. Lancet 2: 193–197.

    PubMed  CAS  Google Scholar 

  • Rothman, KJ, and Fyler, DC (1976) Association of congenital heart defects with season and population density. Teratology 13: 29–34.

    PubMed  CAS  Google Scholar 

  • Rowland, JM, Potter, DE, and Reiter, RJ (1981) Circadian rhythm in intraocular pressure: a rabbit model. Curr Eye Res 1: 169–173.

    PubMed  CAS  Google Scholar 

  • Rutstein, DD, Nickerson, RI, and Heald, FP (1952) Seasonal incidence of patent ductus arteriosus and maternal rubella. Am J Dis Child 84: 199–213.

    CAS  Google Scholar 

  • Salber, EJ, and Bradshaw, ES (1952) Birth weights of South African babies. III. Seasonal variation in birth weight. Br J Soc Med 6: 190–191.

    PubMed  CAS  Google Scholar 

  • Sandahl, B (1974) A study of seasonal and secular trends in incidence of stillbirths and spontaneous abortions in Sweden. Acta Obstet Gynecol Scand 53: 251–257.

    PubMed  CAS  Google Scholar 

  • Sandahl, B (1977) Seasonal incidence of some congenital malformations in the central nervous system in Sweden, 1965–1972. Acta Paediatr Scand 66: 65–72.

    PubMed  CAS  Google Scholar 

  • Sargent, F (1967) Introduction to human biometeorology: Its concepts and problems. In: Seminar on Human Biometeorology. Environmental health Series: Air Pollution. U.S.D.H.E.W., Public Health Service Publication No. 999-AP-25, pp. 1–23.

    Google Scholar 

  • Sauerbier, I (1979) Circadian aspects of the teratogenicity of cytostatic drugs. Chronobiologia 6: 152.

    Google Scholar 

  • Sauerbier, I (1980) Recent findings relative to teratology and chronobiology. In: Scheving, LE, and Halberg, F (eds), Chronobiology: Principles and Applications to Shifts in Schedules. Alphen aan den Rijn, The Netherlands: Sijthoff and Noordhoff, pp. 535–540.

    Google Scholar 

  • Saundby, R, Moynihan, BGA, Maylard, AE, and Herschell, G (1909) Diagnosis in stomach surgery/The diagnostic value of hunger pain. Br Med J 1: 814–815.

    Google Scholar 

  • Schenck, E, and Kruschke, U (1975) Familial progressive dystonia with diurnal fluctuation. Klin Wochenschr 53: 779–780.

    PubMed  CAS  Google Scholar 

  • Scott, JT (1960) Morning stiffness in rheumatoid arthritis. Ann Rheum Dis 19: 361–368.

    PubMed  CAS  Google Scholar 

  • Segawa, M, Hosaka, A, Miyagawa, F, Nomura, Y and Imai, H (1976) Hereditary progressive dystonia with marked diurnal fluctuation. Adv Neurol 14: 215–233.

    PubMed  CAS  Google Scholar 

  • Sensi, S, Manzoli, U, Capani, F, Domenichelli, B, Lucente, M, Schiavoni, G, and Coppola, E (1980) Circadian rhythm of ventricular ectopy. Chest 77: 580.

    PubMed  CAS  Google Scholar 

  • Shackelford, PG, and Feigin, RD (1973) Periodicity of susceptibility to pneumococcal infection: influence of light and adrenocortical secretions. Science 182: 285–287.

    PubMed  CAS  Google Scholar 

  • Shelley, WB, Preucel, RW, and Spoont, SS (1964) Autoimmune progesterone dermatitis. JAMA 190: 35–38.

    PubMed  CAS  Google Scholar 

  • Shifrine, M, Garsd, A, and Rosenblatt, LA (1982) Seasonal variation in immunity of humans. J Interdiscipl Cycle Res 13: 157–165.

    Google Scholar 

  • Shifrine, M, Rosenblatt, LS, Taylor, N, Hetherington, NW, Matthews, VJ, and Wilson, FD (1980a) Seasonal variations in lectin-induced lymphocyte transformation in beagle dogs. J Interdiscipl Cycle Res 11: 219–226.

    Google Scholar 

  • Shifrine, M, Taylor, NJ, Rosenblatt, LS, and Wilson, FD (1980b) Seasonal variation in cell-mediated immunity of clinically normal dogs. Exp Hematol 8: 318–326.

    PubMed  CAS  Google Scholar 

  • Siehr, P (1899) Zwei Fälle von Paralysis agitans im jugendlichen Alter. Dissertation: Königsberg.

    Google Scholar 

  • Simpson, HW (1977) Aspects of cancer chronotherapy: mammary chronothermography and its perspective for treatment of breast carcinoma. In: 14th Therapeutic International Congress, Montpellier, France. Paris: Expansion Scientifique, pp. 197–210.

    Google Scholar 

  • Siracusa, A, Curradi, F, and Abbritti, G (1978) Recurrent nocturnal asthma due to toluene di-isocyanate: a case report. Clin Allergy 8: 195–201.

    PubMed  CAS  Google Scholar 

  • Slater, BCS, Watson, GI, and McDonald, JC (1964) Seasonal variation in congenital abnormalities. Preliminary report of a survey conducted by the research committee of council of the college of general practitioners. Br J Prey Soc Med 18: 1–7.

    CAS  Google Scholar 

  • Slatis, HM, and DeCloux, RJ (1967) Seasonal variation in stillbirth frequencies. Hum Biol 39: 284–294.

    Google Scholar 

  • Smals, AGH, Kloppenborg, PWC, and Benraad, TJ (1976) Circannual cycle in plasma testosterone levels in man. J Clin Endocrinol Metab 42: 979–982.

    PubMed  CAS  Google Scholar 

  • Smolensky, MH (1973) Chronobiology applied to therapy of human breast cancer. In: Time: The Fourth Dimension of Medicine, Vol. 2. New Orleans, La.: Upjohn Symposium, November 3–4, 1973, pp. 6–7.

    Google Scholar 

  • Smolensky, MH (1975) Chronobiologic aspects of cutaneous reactivity, an example of endogenous rhythmicity and implications upon the evaluation of environmental quality. In: Gervais, P. (ed), Asthme, Allergie Respiratoire et Environnement Socio-Écologique. Le Mont-Dore, pp. 41–60.

    Google Scholar 

  • Smolensky, MH (1980) Chronobiologic aspects of the epidemiology of human reproduction and fertility. In: Ortavant, R, and Reinberg, A (eds), Rythmes et Reproduction. Paris: Masson, pp. 219–242.

    Google Scholar 

  • Smolensky, MH (1981) Chronobiologic factors related to the epidemiology of human reproduction. In: Cortés-Prieto, J, Campos da Paz, A, and Nevese-Castro, M (eds), Research on Fertility and Sterility. Lancaster: MTP Press, pp. 157–181.

    Google Scholar 

  • Smolensky, MH, Bicakova-Rocher, A, Reinberg, A, and Sanford, J (1981a) Chronoepidemiological search for circannual changes in the sexual activity of human males. Chrono-biologia 8: 217–230.

    CAS  Google Scholar 

  • Smolensky, MH, and Halberg, F (1977) Circadian rhythms in airway patency and lung volumes. In: McGovern, JP, Smolensky, MH, and Reinberg, A (eds), Chronobiology in Allergy and Immunology. Springfield, IL: Thomas, pp. 117–138.

    Google Scholar 

  • Smolensky, MH, Halberg, F, Reinberg, A, and Stupfel, M (1974) CO2 respiratory regulation and chronobiology. In: Nahas, G, and Schafer, KE (eds), Carbon Dioxide. New York: Springer-Verlag, pp. 118–124.

    Google Scholar 

  • Smolensky, MH, Halberg, F, and Sargent, F (1972) Chronobiology of the life sequence. In: Itoh, S, Ogata, K, and Yoshimura, H (eds), Advances in Climatic Physiology. Tokyo: Igaku Shoin, pp. 281–318.

    Google Scholar 

  • Smolensky, MH, Reinberg, A, Lee, RE, and McGovern, JP (1973) Secondary rhythms related to hormonal changes in the menstrual cycle: Special reference to allergology. In: Perin, M, Halberg, F, Richart, RM, and Vande Wiele, RL (eds), Biorhythms and Human Reproduction. New York: Wiley, pp. 287–306.

    Google Scholar 

  • Smolensky, MH, Reinberg, A, Prevost, RJ, McGovern, JP, and Gervais, P (1980) The application of chronobiologic findings and methods to the epidemiological investigation of the health effects of air pollutants on sentinel patients. In: Smolensky, MH, Reinberg, A, and McGovern, JP (eds), Recent Advances in the Chronobiology of Allergy and Immunology. Oxford: Pergamon Press, pp. 211–236.

    Google Scholar 

  • Smolensky, MH, Reinberg, A, and Queng, J (1981b) The chronobiology and chronopharmacology of allergy. Ann Allergy 47 (4): 234–252.

    PubMed  CAS  Google Scholar 

  • Smolensky, MH, Tatar, SE, Bergman, SA, Losman, JG, Barnard, CN, Dacso, CC, and Kraft, IA (1976) Circadian rhythmic aspects of human cardiovascular function: a review by chronobiologic statistical methods. Chronobiologia 3: 337–371.

    PubMed  CAS  Google Scholar 

  • Soutar, CA, Carruthers, M, and Pickering, CA (1977) Nocturnal asthma and urinary adrenaline and noradrenaline excretion. Thorax 32: 677–683.

    PubMed  CAS  Google Scholar 

  • Soutar, CA, Costello, J, Ijaduola, O, and Turner-Warwick, M (1975) Nocturnal and morning asthma. Relationship to plasma corticosteroids and response to cortisol infusion. Thorax 30: 436–440.

    Google Scholar 

  • Steinbach, K, Eder, A, Glogar, D, Joskowicz, G, and Weber, H (1978) Circadian variations in the frequency of arrhythmia and quantitative analysis of rhythm disturbances. Acta Med Aust 5: 132–134.

    CAS  Google Scholar 

  • Stempel, DA, Davis, VL, Moussey, LJ, and Helms, RW (1981) Seasonal variations of serum IgE levels in normal children. Ann Allergy 47: 14–16.

    PubMed  CAS  Google Scholar 

  • Stephens, S, Smolensky, MH, Kennelly, BM (in preparation) Temporal factors in cardiac morbidity.

    Google Scholar 

  • Stoller, A and Collmann, RD (1965) Incidence of infective hepatitis followed by Down’s syndrome nine months later. Lancet 2: 1221–1223.

    PubMed  CAS  Google Scholar 

  • Strempel, H (1977) Circadian cycles of epicritic and protopathic pain threshold. J Interdiscipl Cycle Res 8: 276–280.

    Google Scholar 

  • Suda, M, Hayaishi, O, and Nakagawa, H (eds) (1979) Biological Rhythms and Their Central Mechanism: A NATO Foundation Symposium. Amsterdam: Elsevier/North Holland Biomedical Press.

    Google Scholar 

  • Symonds, C (1956) A particular variety of headache. Brain 79: 217–232.

    PubMed  CAS  Google Scholar 

  • Tähti, E (1956) Studies of the effect of X-radiation on 24-hour variations in the mitotic activity in human malignant tumours. Acta Pathol Microbiol Scand (Suppl) 117: 1–61.

    Google Scholar 

  • Tammeling, GJ, DeVries, K, and Kruyt, EW (1977) Circadian pattern of bronchial reactivity to histamine in healthy subjects and in patients with obstructive lung-disease. In: McGovern, JP, Smolensky, MH, and Reinberg, A (eds), Chronobiology in Allergy and Immunology. Springfield, IL: Thomas, pp. 139–149.

    Google Scholar 

  • Tarquini, B (1978) Nouve vedute sull’ulcera peptica. Recent Prog Med 64: 24–44.

    CAS  Google Scholar 

  • Tarquini, B, Brocchi, A, Buricchi, L, Cappelli, G, Costa, A, Neri, B, and Cagnoni, M (1977) Circadian study on serum gastrin in patients with duodenal ulcers and in a control group. Chronobiologia 4: 49–55.

    PubMed  CAS  Google Scholar 

  • Tarquini, B, Rosati, I, Serantoni, C, Orzales, R, Ciani, P, Cagnoni, M, and Rosene, G (1976) Circadian studies on gastric mitotic index in patients with duodenal ulcer and in a control group. Chir Gastroenterol 11: 369–371.

    Google Scholar 

  • Tarquini, B, Rosati, I, Serantoni, C, Orzales, R, Ciani, P, Cagnoni, M, and Rosene, G (1976) Circadian studies on gastric mitotic index in patients with duodenal ulcer and in a control group. Chir Gastroenterol 11: 369–371.

    Google Scholar 

  • Taylor, AN, Longbottom, JL, and Pepys, J (1977) Respiratory allergy to urine proteins of rats and mice. Lancet 2 (8043): 847–849.

    PubMed  CAS  Google Scholar 

  • Thiry, A, Heusghem, C, and Legentil, P (1954) Study of the urinary excretion of estrogens, 17-ketosteroids and reducing steroids in epilepsy, particularly the so-called catamenial epilepsy. Rev Med Liege 9: 238–246.

    PubMed  CAS  Google Scholar 

  • Thomas, CB, Holljes, HWD, and Eisenberg, FF (1961) Observation on seasonal variation in total serum cholesterol level among healthy young prisoners. Ann Intern Med 54: 413–430.

    PubMed  CAS  Google Scholar 

  • Tjoa, WK, Smolensky, MH, Hsi, BP, Stein-berger, E, and Smith, KD (1982) Circannual rhythm in human sperm count revealed by serially independent sampling. J Fertil Infertil 38: 454–459.

    CAS  Google Scholar 

  • Todisco, T, Grassi, V, Dorbini, CA, Sottorini, M, de Benedictis, FM, Costellucci, G, and Romano, S (1980) Circadian rhythms of respiratory functions in asthmatics. Respiration 40: 128–135.

    PubMed  CAS  Google Scholar 

  • Tonnesen, MG, Jubiz, W, Moore, JG, and Frailey, J (1974) Circadian variation of prostaglandin E(PGE) production in human gastric juice. Am J Dig Dis 19: 644–648.

    PubMed  CAS  Google Scholar 

  • Toole, JF (1968) Nocturnal strokes and arterial hypotension. Ann Intern Med 68: 1132–1133.

    PubMed  CAS  Google Scholar 

  • Townsend, RE, Prinz, PN, and Obrist, WD (1973) Human cerebral blood flow during sleep and waking. J Appl Physiol 35: 620–625.

    PubMed  CAS  Google Scholar 

  • Tromovitch, TA, and Heggli, WF (1967) Autoimmune progesterone urticaria. Calif Med 106: 211–212.

    PubMed  CAS  Google Scholar 

  • Tromp, SW (1963) Medical Biometeorology: Weather, Climate and the Living Organism. New York: American Elsevier.

    Google Scholar 

  • Trousseau, A (1865) Clinique Médicale de l’Hôtel Dieu de Paris, Vol. 2. Asthme. Paris: Baillière, p. 373.

    Google Scholar 

  • Udry, JR, and Morris, NM (1967) Seasonality of coitus and seasonality of birth. Demography 4: 673–680.

    PubMed  CAS  Google Scholar 

  • Van Cauter, E (1973) Problémes dans l’analyse des séries chronologiques courtes. Mémoire, de licence en Sciences actuarielles. Faculté des Sciences, Université Libre de Bruxelles.

    Google Scholar 

  • Voigt, ED, Engle, P, and Klein, H (1967) Daily fluctuations of the performance-pulse index. Germ Med Mon 12: 394–395.

    Google Scholar 

  • Voutilainen, A (1953) Ueber die 24-Stunden-Rhythmik der Mitosenfrequenz in malignen Tumoren. Acta Pathol Microbiol Scand (Suppl) 99: 1–104.

    CAS  Google Scholar 

  • Watanabe, G, and Aoki, S (1956) Climatic effect on the serum cholesterol levels. Jpn J Med Prog 43: 301–306.

    Google Scholar 

  • Waters, WE, and O’Connor, PJ (1971) Epidemiology of headache and migraine in women. J Neurol Neurosurg Psychiat 34: 148–153.

    PubMed  CAS  Google Scholar 

  • Weitzman, ED (1981) Sleep and its disorders. Ann Rev Neurosci 4: 381–417.

    PubMed  CAS  Google Scholar 

  • Weitzman, ED, Czeisler, CA, Coleman, RM, Spielman, AJ, Zimmerman, JC, Dement, W, Richardson, G, and Pollak, CP (1981) Delayed sleep phase syndrome. A chronobiological disorder with sleep-onset insomnia. Arch Gen Psychiat 38: 737–46.

    PubMed  CAS  Google Scholar 

  • Weitzman, ED, Czeisler, CA, Zimmerman, JC, Ronda, JM, and Knauer, RS (1982) Chrono-biologic disorders: analytic and therapeutic techniques. In: Guilleminault C (ed) Sleeping and Waking Disorders. Calif.: Addison Wesley pp. 167–188.

    Google Scholar 

  • Wertheimer, L, Hassen, AZ, and Delman, AJ (1972) The 24-hour (circadian) rhythm of the cardiovascular system. Clin Res 20: 404.

    Google Scholar 

  • Wesche, DL, and Frederickson, RCA (1981) The role of the pituitary in the diurnal variation in tolerance to painful stimuli and brain enkephalin levels. Life Sci 29: 2199.

    PubMed  CAS  Google Scholar 

  • Wolff, HG (1963) Headache and Other Head Pain. New York: Oxford University Press.

    Google Scholar 

  • Wongwiwat, M, Sukapanit, S, Triyanond, C, and Sawyer, WD (1972) Circadian rhythm of the resistance of mice to acute pneumococcal infection. Infect Immunol 5: 442–448.

    CAS  Google Scholar 

  • Wright, RA, and Judson, FN (1978) Relative and seasonal incidences of the sexually transmitted diseases-2-year statistical review. J Vener Dis 54: 433–440.

    CAS  Google Scholar 

  • Wulfsohn, NL, and Politzer, WM (1964) Bronchial asthma during menses and pregnancy. S Mr Med J 38: 173.

    CAS  Google Scholar 

  • Yamamura, Y, Sobue, I, Ando, K, Lida, M, Yanagi, T, and Kono, C (1973) Paralysis agitans of early onset with marked diurnal fluctuation of symptoms. Neurology 23: 239–244.

    PubMed  CAS  Google Scholar 

  • Yasue, H, Omote, S, Takizawa, A, Nagao, M, Miwa, K, Kato, H, Tanaka, S, and Akiyama, F (1978) Pathogenesis and treatment of angina pectoris at rest as seen from its response to various drugs. Jpn Circ J 42: 1–10.

    PubMed  CAS  Google Scholar 

  • Yasue, H, Omote, S, Takizawa, A., Nagao, M, Miwa, K, and Tanaka, S (1979) Circadian variation of exercise capacity in patients with Prinzmetal’s variant angina: role of exercise-induced coronary arterial spasm. Circulation 59: 938–948.

    PubMed  CAS  Google Scholar 

  • Zondech, B, and Bromberg, YM (1947) Endocrine allergy: clinical reaction of allergy to endogenous hormones and their treatment. J Obstet Gynecol Br Comm 54: 1–19.

    Google Scholar 

  • Zuckerman, S (1957) The human breeding season. New Scientist 1: 12–20.

    Google Scholar 

Download references

Authors
  1. Michael H. Smolensky
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

Copyright information

© 1983 Springer-Verlag New York Inc.

About this paper

Cite this paper

Smolensky, M.H. (1983). Aspects of Human Chronopathology. In: Biological Rhythms and Medicine. Topics in Environmental Physiology and Medicine. Springer, New York, NY. https://doi.org/10.1007/978-1-4613-9496-9_5

Download citation

  • DOI: https://doi.org/10.1007/978-1-4613-9496-9_5

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4613-9498-3

  • Online ISBN: 978-1-4613-9496-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation