Abstract
In 1942 Terry described several children who had leukocoria and a clear lens. He postulated that this entity represented an overgrowth of the vascular tunica. Since then we have learned that this retinopathy occurs to a great degree in premature children. A plethora of factors have been incriminated over time, such as oxygen, sepsis, shifting of the oxygen curve, and bronchodysplasia. These children seem to be born with a fair amount of undeveloped retina, as vascularization is not completed until 1 month after birth. It is a switch from orderly angiogenesis to disorderly proliferation that produces the retinopathy of prematurity (ROP).
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© 1993 Springer Science+Business Media New York
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Orellana, J., Friedman, A.H. (1993). Retinopathy of Prematurity. In: Clinico-Pathological Atlas of Congenital Fundus Disorders. Springer, New York, NY. https://doi.org/10.1007/978-1-4613-9320-7_18
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DOI: https://doi.org/10.1007/978-1-4613-9320-7_18
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