Intracellular pH Regulation by the Preimplantation Embryo

  • Jay M. Baltz
  • John D. Biggers
  • Claude Lechene
Conference paper
Part of the Serono Symposia, USA Norwell, Massachusetts book series (SERONOSYMP)


It has become clear that the preimplantation embryo possesses a number of rapidly developing and sometimes unique systems for transmembrane transport. For example, mouse embryos possess amino acid transport systems that change from one set to a different set, found only in embryos, over the course of only a few days’ development (1); excitable calcium channels are found in abundance in the early mouse and hamster embryo, but disappear completely by the 16-cell stage (2–4); and Na+ transport into the rabbit blastocoel is completely altered between the 5th and 7th day of development, with the development of amiloride and furosemide sensitivity (5, 6).


Preimplantation Embryo Acid Load Antiporter Activity Proton Permeability Large Rate Constant 
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Copyright information

© Springer-Verlag New York, Inc. 1993

Authors and Affiliations

  • Jay M. Baltz
  • John D. Biggers
  • Claude Lechene

There are no affiliations available

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