Abstract
Energy metabolism is ultimately concerned with the generation and utilization of ATP. These two aspects will be considered in turn.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Auerbach S, Brinster RL. Effect of oxygen concentration on the development of two-cell mouse embryos. Nature (London) 1968;217:465–6.
Thomson JL. Effect of inhibitors of carbohydrate metabolism on the development of preimplantation mouse embryos. Exp Cell Res 1967;46:252–62.
Leese HJ. The formation and function of oviduct fluid. J Reprod Fertil 1987;82:843–56.
Yochim JM. Intrauterine oxygen tension and metabolism of the endometrium during the preimplantation period. In: Blandau RJ, ed. The biology of the blastocyst. University of Chicago Press, 1971:363–82.
Mills RM, Brinster RL. Oxygen consumption of preimplantation mouse embryos. Exp Cell Res 1967;47:337–44.
Sellens MH, Stein S, Sherman MI. Protein and free amino acid content in preimplantation mouse embryos and in blastocysts under various culture conditions. J Reprod Fertil 1981;61:307–15.
Stern S, Biggers JD, Anderson E. Mitochondria and early development of the mouse. J Exp Zool 1971;176:179–92.
Leese HJ. Metabolism of the preimplantation mammalian embryo. In: Milligan SR, ed. Oxford reviews of reproductive biology; 13. Oxford University Press, 1991:35–72.
Betteridge KJ, Fléchon J-E. The anatomy and physiology of preattachment bovine embryos. Theriogenology 1988;29:155–87.
Kane MT. Minimal nutrient requirements for culture of one-cell rabbit embryos. Biol Reprod 1987;37:775–8.
Biggers JD. Pioneering mammalian embryo culture. In: Bavister BD, ed. The mammalian preimplantation embryo: regulation of growth and differentiation in vitro. New York: Plenum Press, 1987:1–22.
Pemble LB, Kaye PL. Whole protein uptake and metabolism by mouse blastocysts. J Reprod Fertil 1986;78:149–57.
Leese HJ. The environment of the preimplantation embryo. In: Edwards RG, ed. Establishing a successful human pregnancy. Serono Symposia Publications; 66. New York: Raven Press, 1990:143–54.
Brown JJG, Whittingham DG. The roles of pyruvate, lactate and glucose during preimplantation development of embryos from F hybrid mice in vitro. Development 1991;112:99–105.
Gardner DK, Leese HJ. Concentrations of nutrients in mouse oviduct fluid and their effects on embryo development and metabolism in vitro. J Reprod Fertil 1989;88:361–8.
Lawitts JA, Biggers JD. Optimization of mouse embryo culture media using simplex methods. J Reprod Fertil 1991;91:543–56.
Brinster RL. Nutrition and metabolism of the ovum, zygote and blastocyst. In: Greep RO, Astwood EB, eds. Handbook of physiology; vol II. Washington, D.C.: American Physiological Society, 1973:165–85.
Rieger D, Guay P. Measurement of the metabolism of energy substrates in individual bovine blastocysts. J Reprod Fertil 1988;83:585–91.
Leese HJ, Barton AM. Pyruvate and glucose uptake by mouse ova and preimplantation embryos. J Reprod Fertil 1984;32:9–13.
Butler JE, Lechene C, Biggers JD. Noninvasive measurement of glucose uptake by two populations of murine embryos. Biol Reprod 1988;39:779–86.
Hardy K, Hooper MAK, Handyside AH, Rutherford AJ, Winston RML, Leese HJ. Non-invasive measurement of glucose and pyruvate uptake by individual human oocytes and preimplantation embryos. Hum Reprod 1989; 4:188–91.
Brison DR, Leese HJ. Energy metabolism in late preimplantation rat embryos. J Reprod Fertil 1991;93:245–51.
Leese HJ, Lenton EA. Glucose and lactate in human follicular fluid: concentrations and inter-relationships. Hum Reprod 1990;5:915–9.
Gott AL, Hardy K, Winston RML, Leese HJ. The nutrition and environment of the early human embryo. Proc Nutr Soc 1990;17:546–7.
Edirisinghe WR, Wales RG. Influence of environmental factors on the metabolism of glucose by preimplantation mouse embryos in vitro. Aust J Biol Sci 1985;38:411–20.
Gardner DK, Leese HJ. The role of glucose and pyruvate transport in regulating nutrient utilization by preimplantation mouse embryos. Development 1988;194:423–9.
Kelly JM, McBride BW. The sodium pump and other mechanisms of thermogenesis in selected tissues. Proc Nutr Soc 1990;49:185–202.
Merz EA, Brinster RL, Brunner S, Chen HY. Protein degradation during preimplantation development of the mouse. J Reprod Fertil 1981;61:415–8.
Wiebold JL, Anderson GB. Lethality of a tritiated amino acid in early mouse embryos. J Embryol Exp Morphol 1985;88:209–17.
Jung T. Protein synthesis and degradation in non-cultured and in-vitro cultured rabbit blastocysts. J Reprod Fertil 1989;86:507–12.
Biggers JD, Bell JE, Benos DJ. The mammalian blastocyst: transport functions in a developing epithelium. Am J Physiol 1988;255:419–32.
Epstein CJ, Smith SA. Amino acid uptake and protein synthesis in preimplantation mammalian embryos. Dev Biol 1973;33:171–84.
Gardner DK, Clarke RN, Lechene CP, Biggers JD. Development of a noninvasive ultramicrofluorometric method for measuring the uptake of glutamine by single preimplantation mouse embryos. Gamete Res 1989;24:427–38.
Chatot CL, Tasca RJ, Ziomek CA. Glutamine uptake and utilization by preimplantation mouse embryos in CZB medium. J Reprod Fertil 1990; 89:335–46.
Chatot CL, Ziomek CA, Bavister BD, Lewis JL, Torres I. An improved culture medium supports development of random-bred 1-cell mouse embryos in vitro. J Reprod Fertil 1989;86:679–88.
Newsholme EA, Newsholme P, Curi R, Crabtree B, Ardawi MSM. Glutamine metabolism in different tissues: its physiological and pathological importance. In: Kinney JM, Borum PR, eds. Perspectives in clinical nutrition. Baltimore-Munich: Urban & Schwarzenberg, 1989:71–98.
Gott AL, Hardy K, Winston RML, Leese HJ. Non-invasive measurement of pyruvate and glucose uptake and lactate formation by single human preimplantation embryos. Hum Reprod 1990;5:104–8.
Barbehenn EK, Wales RG, Lowry OH. The explanation for the blockade of glycolysis in early mouse embryos. Proc Natl Acad Sci USA 1974;71: 1056–60.
Epstein CJ. Gene expression and macromolecular synthesis during preimplantation embryonic development. Biol Reprod 1975;12:82–105.
Telford NA, Watson AJ, Schultz GA. Transition from maternal to embryonic control in early mammalian development: a comparison of several species. Mol Reprod Dev 1990;26:90–100.
Leese HJ. Energy metabolism of the blastocyst and uterus at implantation. In: Yoshinaga K, ed. Blastocyst implantation. Serono Symposia, USA. Boston: Adams Publishing, 1989:39–44.
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1993 Springer-Verlag New York, Inc.
About this paper
Cite this paper
Leese, H.J. (1993). Energy Metabolism in Preimplantation Development. In: Bavister, B.D. (eds) Preimplantation Embryo Development. Serono Symposia, USA Norwell, Massachusetts. Springer, New York, NY. https://doi.org/10.1007/978-1-4613-9317-7_6
Download citation
DOI: https://doi.org/10.1007/978-1-4613-9317-7_6
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4613-9319-1
Online ISBN: 978-1-4613-9317-7
eBook Packages: Springer Book Archive