Abstract
Molecular studies on insecticide resistance are important for both fundamental and applied research. Resistance has developed so rapidly that we can gather meaningful data on selective changes during evolution (Kimura 1968; Roush and McKenzie 1987). Elucidation of the molecular mechanisms involved may allow for a clearer understanding of the modes of action of insecticides and the pathways for their degradation. Such knowledge could facilitate the rational design of novel insecticidal compounds and help in the formulation of pest control strategies for the future.
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References
Ahmad M, Gladwell RT, McCaffery AR (1989) Decreased nerve sensitivity is a mechanism of resistance in a pyrethriodresistant strain of Heliothis armigerafrom Thailand. Pestic Biochem Physiol 35:165ā171
Arpagaus M, Toutant J-P Alterations in the mucosal immune system in ulcerative colitis and Crohnās disease. Med Clin North Am 1990;78:1207ā1231.
Ashburner M. Maintenance therapy in ulcerative colitis and Crohnās disease. J Clin Gastroenterol 1995;20:117ā122.
Hanauer SB. Medical therapy of ulcerative colitis. Lancet 1993;342:412ā417.
Hanauer SB. Medical therapy in ulcerative colitis. In: Kirsner JB, Shorter RG, eds. Inflammatory bowel disease. 4th ed. Baltimore: Williams & Wilkins, 1995:664ā694.
Meyers S, Sachar DB. Medical therapy of Crohnās disease. In: Kirsner JB, Shorter RG, eds. Inflammatory bowel disease. 4th ed. Baltimore: Williams & Wilkins; 1995:695ā714.
Stark ME, Tremaine WJ. Maintenance of symptomatic remission in patients with Crohnās disease. Mayo Clin Proc 1993;68:1183ā1190.
Svarts N. Sulfasalazine. II. Some notes on the discovery and development of salazopyrin. Am J Gastroenterol 1988;83:497ā503.
Greenfield SM, Punchard NA, Teare JP, et al. Review article: the mode of action of the aminosalicylates in inflammatory bowel disease. Aliment Pharmacol Therapy 1993;7:369ā383.
Hanauer SB, Meyers S, Sachar DB. The pharmacology of anti-inflammatory drugs in inflammatory bowel disease. In: Kirsner JB, Shorter RG, eds. Inflammatory bowel disease. 4th ed. Baltimore: Williams & Wilkins, 1995:643ā663.
Klotz U, Maier K, Fischer C, et al. Therapeutic efficacy of sulfasalazine and its metabolites in patients with ulcerative colitis and Crohnās disease. N Engl J Med 1980;303:1499ā1502.
Eliakim R, Rachmilewitz D. Potential mediators on inflammatory bowel disease. Gastroenterol Intl 1992;5:48ā56.
Grisham MB. Oxidants and free radicals in inflammatory bowel disease. Lancet 1994;344:859ā861.
Lauritsen K, Laursen S, Bukhave K, et al. Inflammatory intermediaries in inflammatory bowel disease. Int J Colorectal Dis 1989;4:75ā90.
Sutherland LR, May GR, Shaffer EA. Sulfasalazine revisited: a meta-analysis of 5-Aminosalicylic acid in the treatment of ulcerative colitis. Ann Int Med 1993;118:540ā549.
Steinhart AH, Hemphill D, Greenberg GR. Sulfasalazine and mesalazine for the maintenance treatment of Crohnās disease: a meta analysis. Am J Gastroenterol 1994;84:2116ā2124.
Malchow H, Ewe K, Brandes JW, et al. European Cooperative Crohnās Disease Study (ECCDS): results of drug treatment. Gastroenterology 1984;86:249ā266.
Margolin ML, Krumholz MP, Fochios SE, et al. Clinical trials in ulcerative colitis: II. Historical review. Am J Gastroenterol 1988;83:227ā243.
Hanauer SB, Stathopoulos G. Risk-benefit assessment of drugs used in the treatment of inflammatory bowel disease. Drug Safety 1991;6:192ā219.
Summers RW, Switz DM, Sessions JT Jr, et al. National Cooperative Crohnās Disease Study (NCCDS): results of drug treatment. Gastroenterology 1979;77:847ā869.
Saloman P, Kornbluth A, Aisenberg J, et al. How effective are current drugs for Crohnās disease? A meta-analysis. J Clin Gastroenterol 1992;14:211ā215.
Das KM, Eastwood MA, McManus JP, et al. Adverse reactions during salicylazosulfapyridine therapy and the relation with drug metabolism and acetylator phenotype. N Engl J Med 1973;289:491.
Taffet SL, Das KM. Sulfasalazine: adverse effects and desensitization. Dig Dis Sci 1983;28:833.
Thomson ABR. Review article: new developments in the use of 5-aminosalicylic acid in patients with inflammatory bowel disease. Aliment Pharmacol Ther 1991;5:449.
Marshall JK, Irvine EJ. Topical aminosalicylate (ASA) therapy for distal ulcerative colitis: a meta-analysis. Gastroenterology 1994;106:A1037.
Hanauer S, Schwartz J, Robinson M, et al. Mesalamine capsules for the treatment of active ulcerative colitis. Results of a controlled trial. Am J Gastroenterol 1993;88:1188ā1197.
Wadworth AN, Ritton A. Olsalazine. A review of its pharmicokinetic properties, and therapeutic potential in inflammatory bowel disease. Drugs 1991;41:647ā664.
Hanauer SB, Baert F. Medical therapy of inflammatory bowel disease. Med Clin North Am 1994;78:1413ā1426.
Singleton JW, Hanauer SB, Gitnick GL, et al, and the Pentasa Crohnās disease study group. Mesalamine capsules for the treatment of active Crohnās disease. Results of a 16 week trial. Gastroenterology 1993;104:1293ā1301.
Messori A, Brignila C, Trallori G, et al. Effectiveness of 5-Aminosalicylic acid for maintaining remission in patients with Crohnās disease: a meta-analysis. Am J Gastroenterol 1994;89:692ā698.
Hanauer SB. Drug therapy: inflammatory bowel disease. N Engl J Med 1996;334:841ā848.
Cohen RD, Hanauer SB. Immunomodulatory agents and other medical therapies in inflammatory bowel disease. Curr Opin Gastroenterol 1995;11:321ā330.
Hawthorne AB, Hawkey CJ. Immunosuppressive drugs in inflammatory bowel disease: a review of their mechanisms of efficacy and place in therapy. Drugs 1989;38:267ā288.
Brattsand R. Overview of newer glucocorticosteroid preparations for inflammatory bowel disease. Can J Gastroenterol 1990;4:407ā414.
Boumpas DT, Chrousos GP, Wilder RL, et al. Glucocorticoid therapy for immune-mediated diseases: basic and clinical correlates. Ann Int Med 1993;119:1198ā1208.
Truelove SC, Witts LJ. Cortisone in ulcerative colitis. Final report on a therapeutic trial. British Med J 1955;2:1041ā1048.
Meyers S, Sachar DB, Goldberg JD, et al. Corticotropin versus hydrocortisone in intravenous treatment of ulcerative colitis. Gastroenterology 1983;85:351ā357.
Baron JH, Connell AM, Kanaghinis TG, et al. Outpatient treatment of ulcerative colitis: comparison between three doses of oral prednisone. Br Med J 1962;2:441ā443.
Lennard-Jones JE. Toward optimal use of corticosteroids in ulcerative colitis and Crohnās disease. Gut 1983;24:177.
Meyers S, Janowitz HD. Systemic corticosteroid therapy of ulcerative colitis. Gastroenterology 1985;89:1189ā1199.
Sutherland LR. Topical treatment of ulcerative colitis. Med Clin North Amer 1990;74:119ā131.
Mulder CJ, Tygat GN. Review article: topical corticosteroids in inflammatory bowel disease. Aliment Pharmacol Ther 1993;7:125ā130.
Danielsson A, Lofberg R, Persson T, et al. A steroid enema, budesonide, lacking systemic effects for the treatment of distal ulcerative colitis or proctitis. Scand J Gastroenterol 1992;27:9ā12.
Shepard HA, Barr GD, Jewel DP. Use of an iv steroid regimen in the treatment of acute Crohnās disease. J Clin Gastroenterol 1986;8(2):154ā159.
Bjarnason I, Hayllar J, MacPherson A, et al. Side effects of nonsteroidal anti-inflammatory drugs on the small and large intestine in humans. Gastroenterology 1993;104:1832ā1847.
Bianchi Porro G, Prantera C, Campieri M, et al. Comparative trial of budesonide and methylpred-nisolone enemas in active distal ulcerative colitis. Eur J Gastroenterol Hepatol 1994;6:125ā130.
Danish Budesonide Study Group. Budesonide enema in distal ulcerative colitis. A randomized dose-response trial with prednisolone enema as a positive control. Scand J Gastroenterol 1991;26:1225ā1230.
Danielsson A, Hellers G, Lyrenas E, et al. A controlled randomized trial of budesonide versus prednisolone retention enemas in active distal ulcerative colitis. Scand J Gastroenterol 1987;22:987.
Rutgeerts, P, Lofberg R, Malchow H, et al. A comparison of budesonide with prednisolone for active Crohnās disease. N Engl J Med 1994;331:842ā845.
Greenberg GR, Feagan GB, et al, and the Canadian Inflammatory Bowel Disease Study Group. Oral budesonide for active Crohnās disease. N Engl J Med 1994;331:836ā841.
Sachar DB. Budesonise for inflammatory bowel disease. Is it the magic bullet? N Engl J Med 1994;331:873ā874.
Greenberg GR, Feagan BG, et al. Oral Budesonide as Maintenance Treatment for Crohnās Disease: a placebo-controlled, dose-ranging study. Gastroenterology 1996;110:299.
Adler DJ, Korelitz BI. The therapeutic efficacy of 6-Mercaptopurine in refractory ulcerative colitis. Am J Gastroenterol 1990;85:712ā722.
Choi PM, Targan SR. Immunomodualatory treatment in inflammatory bowel disease. Dig Dis Sci 1994;39:1885ā1892.
Gearge J, Pou R, Bodain C, et al. 6-Mercaptopurine is effective in chronic ulcerative colitis but how long do you use it? Gastroenterology 1994;106:A686.
Pearson DC, May GR, Fick GH, et al. Azathioprine and 6-MP in Crohnās disease. A meta-analysis. Ann Int Med 1995;122:132ā142.
Ewe K, Press AG, Singe C, et al. Azathioprine combined with prednisolone or monotherapy with prednisolone in active Crohnās disease. Gastroenterology 1993;105:367ā372.
Present DH, Korelitz BI, Wisch N, et al. Treatment of Crohnās disease with 6-mercaptopurine: a long-term randomised, double-blind study. N Engl J Med 1981;302:981ā987.
Present DH, Meltzer SJ, Krumholz MP, et al. 6-mercaptopurine in the management of inflammatory bowel disease: short and long term toxicity. Ann Intern Med 1989;111:641ā649.
Connell WR, Kamm MA, Dickson M, et al. Long-term neoplasia risk after azathioprine treatment in inflammatory bowel disease. Lancet 1994;343:1249ā1252.
Haber DJ, Meltzer SJ, Present DH, et al. Nature and course of pancreatitis caused by 6-mercaptopurine in the treatment of inflammatory bowel disease. Gastroenterology 1986;91:982ā986.
Connell WR, Kamm, MA, Ritchie JK, et al. Bone marrow toxicity caused by azathioprine in inflammatory bowel disease: 27 years of experience. Gut 1993;34:1081ā1085.
Sandborn WJ, Tremaine WJ. Cyclosporine treatment of inflammatory bowel disease. Mayo Clin Proc 1992;67:981ā990.
Lichteger S, Present DH, Kornbluth A, et al. Cyclopsorin in severe ulcerative colitis refractory to steroid therapy. N Engl J Med 1994;330:1841ā1845.
Sandborn WJ. A critical review of cyclosporine therapy in inflammatory bowel disease. Inflammatory Bowel Dis 1995;l:48ā63.
Hanauer SB, Smith MB. Rapid closure of Crohnās disease fistulas with continuous intravenous cyclo-sporin A. Am J Gastroenterol 1993;88:646ā649.
Present DH, Lichtiger S. Efficacy of cyclosporine in treatment of fistula of Crohnās disease. Dig Dis Sci 1994;39:374ā380.
Feagan BG, McDonald JWD, Rochon J, et al, for the Canadian Crohnās Relapse Prevention Trial Investigators. Low dose cyclosporin A for treatment of Crohnās disease. N Engl J Med 1994;330:1846ā1851.
Stange EF, Modigliani R, Pena AS, et al, and The European Study Group. European trial of cyclosporine in chronic active Crohnās disease: a 12-month study. Gastroenterology 1995;109:774ā782.
Baron TH, Truss CD, Elson CO. Low-dose oral methotrexate in refractory inflammatory bowel disease. Dig Dis Sci 1993;38:1851ā1856.
Kozorek RA, Patterson DJ, Gelfand MD, et al. Methotrexate induces clinical and histological remission in patients with refractory inflammatory bowel disease. Ann Int Med 1989;110:353ā356.
Feagan BG, Rochon J, Fedorak RN, et al. Methotrexate for the treatment of Crohnās disease. N Engl J Med 1995;332:292ā297.
Weinblatt BE. Methotrexate for chronic disease in adults. N Engl J Med 1995;332:330ā331.
Morgan SL, Baggott JE, Vaughn WH, et al. Supplementation with folic acid during methotrexate therapy for rheumatoid arthritis. Ann Int Med 1994;121:833ā841.
Sartor RB. Microbial factors in the pathogenesis of Crohnās disease, ulcerative colitis, and experimental intestinal inflammation. In: Kirsner JB, Shorter RG, eds. Inflammatory bowel disease, 4th ed. Baltimore: Williams & Wilkins; 1995:96ā124.
Ursung B, Alm T, Barany F, et al. A comparative study of metronidazole and sulfasalazine for active Crohnās disease: the cooperative Crohnās disease study in Sweden. Gastroenterology 1982;83:550ā562.
Prantera C, Kohn A, Mangiarotti R, et al. Anti-mycobacterial therapy in Crohnās disease: results of a controlled, double-blind trial with a multiple antibiotic regimen. Am J Gastroenterol 1994;89:513ā518.
Hampson SJ, Parker MC, Saverymuttu SH, et al. Results of quadruple antimycobacterial chemotherapy in 17 Crohnās disease patients completing six months of treatment. Gastroenterology 1988;94:A170.
Swift GL, Srivastava ED, Stone R, et al. Controlled trial of anti-tuberculous chemotherapy for two years in Crohnās disease. Gut 1994;35:363ā368.
Peppercorn MA. Are antibiotics useful in management of nontoxic severe ulcerative colitis? J Clin Gastroenterol 1993;17:14ā17.
Chapman RW, Selby WS, Jewel DP. Controlled trial of metronidazole as an adjunct to corticosteroids in severe ulcerative colitis. Gut 1986;27:1210ā1212.
Sandborn WJ. Pouchitis following ileal pouch-anal anastamosis: definition, pathogenesis, and treatment. Gastroenterology 1994;107:1856ā1860.
Sutherland L, Singleton J, Sessions J, et al. Double blind, placebo controlled trial of metronidazole in Crohnās disease. Gut 1991;32:1071ā1075.
Brandt LJ, Bernstein LH, Boley SJ, et al. Metronidazole therapy for perineal Crohnās disease: a follow-up study. Gastroenterology 1982;83:383ā387.
Rutgeerts P, Hick M, Peeters M, et al. Prevention of clinical recurrence after ileal resection for Crohnās disease with metronidazole: a placebo controlled study. Gastroenterology 1994;106:A764.
Peppercorn MA. Is there a role for antibiotics as primary therapy in Crohnās ileitis? J Clin Gastroenterol 1993;17:235ā237.
Turunen U, Farkkila V, Hakala K, et al. A double-blind, placebo controlled six-month ciprofloxacin treatment improved prognosis in ulcerative colitis. Gastroenterology 1994;106:A786.
Turunen U, Farkkila V, Valtonen V, et al. Long-term outcome of ciprofloxacin treatment in severe perianal or fistulous Crohnās disease. Gastroenterology 1993;104:A793.
Stenson WF, Cort D, Rodgers J, et al. Dietary supplementation with fish oil in ulcerative colitis. Ann Intern Med 1992; 116:609ā614.
Hawthorne AB, Daneshmend TK, Hawkey CJ, et al. Treatment of ulcerative colitis with fish oil supplementation: a prospective 12 month randomised controlled trial. Gut 1992;33:922ā928.
Breuer RI, Buto SK, Christ MI, et al. Rectal irrigation with short chain fatty acids for distal ulcerative colitis. Preliminary Report. Dig Dis Sci 1991;36:185ā187.
Steinhart AH, Brzezinski A, Baker JP. Treatment of refractory ulcerative proctosigmoiditis with butyrate enemas. Am J Gastroenterol 1994;89:179ā184.
Scheppach W, Sommer H, Kirchner T, et al. Effect of butyrate enemas on the colonic mucosa in distal ulcerative colitis. Gastroenterology 1992;103:51ā56.
Hanauer SB, Schulman M. Novel therapies for inflammatory bowel disease. Gastro Clin North Amer 1995;24:523ā540.
OāDonnell LJ, Arvind AS, Hoang P, et al. Doubleblind, controlled trial of 4-aminosalicylic acid and prednisolone enemas in distal ulcerative colitis. Gut 1992;33:947ā949.
Bjorck D, Dahlstrom A, Johansson L, et al. Treatment of the mucosa with local anesthetic in ulcerative colitis. Agents Actions Special Conference Issue, C60, 1992.
Lechin F, van der Dijs B, Insausti CL, et al. Treatment of ulcerative colitis with clonidine. J Clin Pharmacol 1985;25:219ā226.
Hanauer SB. Nicotine for colitis. The smoke has not yet cleared. N Engl J Med 1994;330:856ā857.
Cottone M, Roselli M, Orlando A, et al. Smoking habits and recurrence in Crohnās disease. Gastroenterology 1994;106:643ā648.
Pullan RD, Rhodes J, Ganesh S. Transdermal nicotine for active ulcerative colitis. N Engl J Med 1994;330:811ā815.
Thomas GAO, Rhodes J, Mani V, et al. Transdermal nicotine as maintenance therapy for ulcerative colitis. N Engl J Med 1995;332(15):988ā992.
Lavy A, Wwisz G, Adir Y, et al. Hyperbaric oxygen for perianal Crohnās disease. J Clin Gastroenterol 1994;19:202ā205.
Gaffney PR, Doyle CT, Gaffney A, et al. Paradoxical response to heparin in 10 patients with ulcerative colitis. Am J Gastroenterol 1995;90:220ā223.
Bicks RC, Groshart KW, Chandler RW. The treatment of severe chronically active Crohnās disease by T8 (suppressor cell) lymphaphersis. Gastroenterology 1985;88:A1325.
van Dulleman HM, van Derventer SJH, Hommes DW, et al. Treatment of Crohnās disease with antitumor necrosis factor chimeric monoclonal antibody (cA2). Gastroenterology 1995;109:129ā135.
Stronkhorst A, Radema S, ten Berge I, et al. Phase I multiple-dose pilot study of chimeric monoclonal M-T412 (anti-CD-4) antibodies is Crohnās disease. Gastroenterology 1993;104:A784.
Jarnerot G. New salicylates as maintenance treatment in ulcerative colitis. Gut 1994;35:1155ā1158.
Jarnerot G, Rolny P, Sandberg-Gertzen H. Intensive intravenous treatment of ulcerative colitis. Gastroenterology 1985;89:1005ā1013.
Present DH. Toxic megacolon. Med Clin North Am 1993;77:1129ā1148.
Actis GC, Ottobrelli A, Pera A, et al. Continuously infused cyclosporine at low dose is sufficient to avoid emergency colectomy in acute attacks of ulcerative colitis without the need for high-dose steroids. J Clin Gastroenterol 1993;17:10ā13.
Hawthorne AB, Logan RFA, Hawkey CJ, et al. Randomised controlled trial of azathioprine withdrawal in ulcerative colitis. Br Med J 1992;305:20ā22.
Munkholm P, Langholz E, Davidsen M, et al. Frequency of glucocorticoid resistance and dependency in Crohnās disease. Gut 1994;35:360ā362.
Stemberg EM, Chrousos GP, Wilder RL, et al. The stress response and the regulation of inflammatory disease. Ann Int Med 1992;117:854ā866.
Nugent FW, Roy MA. Duodenal Crohnās disease: an analysis of 89 cases. Am J Gastroenterol 1989;84:249ā254.
Valori RM, Cockel R. Omeprazole for duodenal ulceration in Crohnās disease. Br Med J 1990;300:438ā439.
Tan WC, Allan RN. Diffuse jejunoileitis of Crohnās disease. Gut 1993;34:1374ā1378.
Lewis JD, Fisher RL. Nutrition support in inflammatory bowel disease. Med Clin North Am 1994;78:1443ā1456.
Ogorek CP, Fisher RS. Differentiation between Crohnās disease and ulcerative colitis. Med Clin North Am 1994;78:1249ā1258.
Rutgeerts P, Ggeboes K, Vantrappen G, et al. Predictability of the postoperative course of Crohnās disease. Gastroenterology 1990;99:956ā963.
Caprilli R, Castro M, Cirillo LC, et al. Postoperative recurrence in Crohnās disease: definition, prediction and monitoring. Gastroenterol Int 1993;6:145ā148.
Brignola C, Cottone M, Pera A, et al. Mesalamine in the prevention of endoscopic recurrence after intestinal resection for Crohnās disease. Gastroenterology 1994;108:345ā349.
Yu Q, Colot HV, Kyriacou CP, Hall JC (1987) Prophylactic mesalamine treatment decreases postoperative recurrence of Crohnās disease. Gastroenterology 109:404ā413.
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ffrench-Constant, R.H., Roush, R.T., CariƱo, F.A. (1993). Drosophila as a Tool for Investigating the Molecular Genetics of Insecticide Resistance. In: Oakeshott, J., Whitten, M.J. (eds) Molecular Approaches to Fundamental and Applied Entomology. Springer Series in Experimental Entomology. Springer, New York, NY. https://doi.org/10.1007/978-1-4613-9217-0_1
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