Abstract
Cellular proliferation involves different regulatory molecules that include hormones and growth factors. Interestingly, progestins can stimulate as well as inhibit the growth of tumors depending on the experimental design (1). In mammary cancer, polypeptide growth factors, such as EGF, TGFα, TGFβ, and IGF-I, IGF-II, may play either an autocrine or a paracrine role. The present study investigates the presence of these factors and their receptors in mammary adenocarcinomas induced by medroxyprogesterone acetate (MPA).
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© 1992 Springer-Verlag New York, Inc.
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Charreau, E.H., Elizalde, P., Guerra, F., Lanari, C., Kordon, E., Pasqualini, C.D. (1992). Growth Factors in Murine Mammary Adenocarcinomas Induced by Progestins. In: Li, J.J., Nandi, S., Li, S.A. (eds) Hormonal Carcinogenesis. Springer, New York, NY. https://doi.org/10.1007/978-1-4613-9208-8_19
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DOI: https://doi.org/10.1007/978-1-4613-9208-8_19
Publisher Name: Springer, New York, NY
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