Abstract
Hepatic cytochrome P-450 (P-450) is a family of enzyme forms predominantly located in the smooth endoplasmic reticulum of hepatocytes. These enzymes are active in the metabolism of an extensive range of endogenous and xenobiotic compounds. P-450s can be classified as being constitutive or inducible. By defmition, constitutive forms of P-450 are found in normal untreated animals, while inducible P-450s increase in concentration, often from undetectable levels, following exposure to certain xenobiotic compounds.
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© 1992 Springer-Verlag New York, Inc.
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Liddle, C., Legraverend, C., Blanck, A., Porsch-Hällström, I., Mode, A., Gustafsson, JÅ. (1992). Sexual Dimorphism of Hepatic Steroid Metabolism and Its Significance for Chemical Hepatocarcinogenesis. In: Li, J.J., Nandi, S., Li, S.A. (eds) Hormonal Carcinogenesis. Springer, New York, NY. https://doi.org/10.1007/978-1-4613-9208-8_17
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DOI: https://doi.org/10.1007/978-1-4613-9208-8_17
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