Abstract
Electrophoresis is a method for size-separation of charged polymers using electric field. A gel is a network of cross-linked polymers; see Figure 9.1. The principle of electrophoresis in a gel is very simple. When charged polymers are free to move in a gel, subject to an electric field, their mobilities within the gel are size-dependent. Consequently, as they have moved from one side of a container to another, they become separated according to their size. Electrophoresis is an important technique for DNA mapping: after cutting DNA molecules with enzymes, one can separate the various segments by electrophoresis.
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© 1991 Springer-Verlag New York Inc.
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Friedman, A. (1991). A three-state model for gel electrophoresis. In: Mathematics in Industrial Problems. The IMA Volumes in Mathematics and its Applications, vol 38. Springer, New York, NY. https://doi.org/10.1007/978-1-4613-9177-7_9
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DOI: https://doi.org/10.1007/978-1-4613-9177-7_9
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