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Interleukin-2 Receptors on Monocytes and Their Relation to the Process of Monocytic Cell Differentiation

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Book cover Experimental Hematology Today—1989

Part of the book series: Experimental Hematology Today—1989 ((HEMATOLOGY,volume 1989))

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Abstract

Resting T lymphocytes when activated by exposure to antigen or mitogen induce and amplify their own proliferation by producing a glycoprotein hormone called T cell growth factor or inteiieukin 2 (IL2) [1]. One of the classical markers of activated T cells is the subseqent expression of specific membrane receptors for interleukin 2 (IL2R) [2]. The expression of these receptors on T cells was shown to be a transient event [3] and restimulation with either antigen or mitogen is required for continous IL2R expression and maintainance of T cell proliferative capacity.

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Authors
  1. S. Ruhl
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  2. G. C. Begley
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  3. M. Bickel
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  4. H. Pluznik
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Editor information

Editors and Affiliations

  1. Department of Hematology, Saint-Antoine Hospital, 184, rue du Faubourg Saint-Antoine, 75571, Paris, France

    Norbert C. Gorin M.D.  & Luc Douay M.D.  & 

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© 1990 Springer-Verlag New York Inc.

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Ruhl, S., Begley, G.C., Bickel, M., Pluznik, H. (1990). Interleukin-2 Receptors on Monocytes and Their Relation to the Process of Monocytic Cell Differentiation. In: Gorin, N.C., Douay, L. (eds) Experimental Hematology Today—1989. Experimental Hematology Today—1989, vol 1989. Springer, New York, NY. https://doi.org/10.1007/978-1-4613-9003-9_6

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  • DOI: https://doi.org/10.1007/978-1-4613-9003-9_6

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4613-9005-3

  • Online ISBN: 978-1-4613-9003-9

  • eBook Packages: Springer Book Archive

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