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Interleukin-2 Receptors on Monocytes and Their Relation to the Process of Monocytic Cell Differentiation

  • S. Ruhl
  • G. C. Begley
  • M. Bickel
  • H. Pluznik
Conference paper
Part of the Experimental Hematology Today—1989 book series (HEMATOLOGY, volume 1989)

Abstract

Resting T lymphocytes when activated by exposure to antigen or mitogen induce and amplify their own proliferation by producing a glycoprotein hormone called T cell growth factor or inteiieukin 2 (IL2) [1]. One of the classical markers of activated T cells is the subseqent expression of specific membrane receptors for interleukin 2 (IL2R) [2]. The expression of these receptors on T cells was shown to be a transient event [3] and restimulation with either antigen or mitogen is required for continous IL2R expression and maintainance of T cell proliferative capacity.

Keywords

Monocytic Cell IL2R Expression Human Peripheral Blood Monocyte Mature Macrophage Cell Proliferative Capacity 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag New York Inc. 1990

Authors and Affiliations

  • S. Ruhl
  • G. C. Begley
  • M. Bickel
  • H. Pluznik

There are no affiliations available

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