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Granulocyte Colony-Stimulating Factor

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Experimental Hematology Today—1988

Part of the book series: Experimental Hematology Today—1988 ((HEMATOLOGY,volume 1988))

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Abstract

The independent (1,2) establishment of in vitro culture systems for hemopoietic progenitor cells has allowed the identification of various hormones which regulate blood cell production and differentiation. These glycoproteins, known as colony-stimulating factors (CSFs) were originally purified from the conditioned media of a number of diverse sources, including placenta, tumor cell lines, and peripheral blood mononuclear cells. The factors were initially named according to the predominant colony type their addition produced in cultures of bone marrow cells (3). Currently in the human system, several CSF’s have been defined which act in a hierarchical fashion and which possess varying lineage specificity.

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Authors
  1. K. McD. Taylor
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  2. G. Spitzer
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  3. L. Souza
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Editor information

Editors and Affiliations

  1. International Society for Experimental Hematology, Bethesda, Maryland, 20817, USA

    S. J. Baum (Treasurer) (Treasurer)

  2. Bone Marrow Transplantation Section, Department of Hematology, University of Texas M.D. Anderson Cancer Center, Houston, Texas, 77030, USA

    K. A. Dicke

  3. Section of Natural Immunity, Department of General Surgery, University of Texas M.D. Anderson Cancer Center, Houston, Texas, 77030, USA

    E. Lotzová

  4. Laboratory of Immunology, National Institute of Dental Research, National Institutes of Health, Bethesda, Marlyand, 20892, USA

    D. H. Pluznik

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© 1989 Springer Science+Business Media New York

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Taylor, K.M., Spitzer, G., Souza, L. (1989). Granulocyte Colony-Stimulating Factor. In: Baum, S.J., Dicke, K.A., Lotzová, E., Pluznik, D.H. (eds) Experimental Hematology Today—1988. Experimental Hematology Today—1988, vol 1988. Springer, New York, NY. https://doi.org/10.1007/978-1-4613-8862-3_9

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  • DOI: https://doi.org/10.1007/978-1-4613-8862-3_9

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4613-8864-7

  • Online ISBN: 978-1-4613-8862-3

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