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Age-Related Changes in Left Ventricular/Arterial Coupling

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Abstract

To understand the influence of the aging process on left ventricular/arterial coupling (or interaction), it is important first to consider the effects of age on ventricular and arterial functions separately. The function of the left ventricle is to pump blood (the cardiac output) through the systemic arterial system to the organs and tissues in an amount sufficient to meet their metabolic requirements. The arterial system has two distinct and separate functions: (1) It serves as a vascular conduit system that delivers blood at high pressure to the various peripheral beds and (2) it serves as a buffering system (Windkessel) that smooths out pulsations resulting from intermittent ventricular ejection so that the capillaries receive a steady or continuous flow of blood.

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Nichols, W.W. et al. (1987). Age-Related Changes in Left Ventricular/Arterial Coupling. In: Yin, F.C.P. (eds) Ventricular/Vascular Coupling. Springer, New York, NY. https://doi.org/10.1007/978-1-4613-8634-6_4

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  • DOI: https://doi.org/10.1007/978-1-4613-8634-6_4

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