Changing Hemodynamics and Lung Perfusion before and after Anatomic Correction of Transposition of the Great Arteries by Computer Angiography

  • L. M. Gravinghoff
  • R. Radley-Smith
  • M. Yacoub
  • E. W. Keck


Since Jatene (1976) first published a new approach to surgical correction of transposition of the great arteries (TGA), several centers have been accumulating experience with this method. At present, it is accepted that anatomic correction of TGA is a true alternative to other procedures (Mustard and Senning) [1–4]. One of the disadvantages in simple TGA is the necessity of a preliminary procedure; banding of pulmonary artery to train the left ventricle and subclavian artery to pulmonary artery shunt to increase the reduced pulmonary flow. This approach may require up to four cardiac catheterizations. We became especially interested in obtaining information about changes in pulmonary blood flow. In earlier studies, we could demonstrate changes in pulmonary flow and resistance by digital image processing of routine right ventricular (RV cineangiograms, with estimation of the arrival time (AT) of contrast bolus in the lung periphery [5]. Therefore, it seemed interesting to study the changing lung perfusion in TGA patients undergoing two-stage anatomic correction.


Arrival Time Pulmonary Blood Flow Lung Perfusion Contrast Bolus Pulmonary Flow 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Jatene A, Fontes VF, Paulista PD, Et Al: Anatomic correction of transposition of the great vessels. J Thoracic Cardiovasc Surg 72: 364–370, 1976.Google Scholar
  2. 2.
    Yacoub MH, Bernhard A, Radley-Smith R, Et Al: Supravalvar pulmonary stenosis after anatomic correction of TGA: causes and prevention. Circulation 66 (Suppl I): 1193–1197, 1982.Google Scholar
  3. 3.
    Bernhard A, Yacoub M, Regensburger D, Et Al: Further experience with the two-stage anatomic correction of simple TGA. Thoracic Cardiovasc Surg 29: 138–142, 1981.CrossRefGoogle Scholar
  4. 4.
    Jatene A, Fontes VF, Souza LCB, Et Al: Anatomic correction of TGA. J Thoracic Cardiovasc Surg 83: 20–26, 1982.Google Scholar
  5. 5.
    Riediger G, Gravinghoff L, Hohne KH,Keck EW: Evaluation of pulmonary arrival time of contrast medium in Ventricular Septal Defects by means of Computer-Angiography (in preparation).Google Scholar
  6. 6.
    Höhne KH, Böhm M, Erbe W, Et Al: Computer-Angiography: a new tool for X-ray functional diagnostics. Med Prog Technol 6: 23, 1978.PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1986

Authors and Affiliations

  • L. M. Gravinghoff
  • R. Radley-Smith
  • M. Yacoub
  • E. W. Keck

There are no affiliations available

Personalised recommendations