A High Risk of Heart Defects among the Offspring of Parents Affected with Four Types of Congenital Heart Disease
We have examined the incidence of congenital heart disease among offspring of parents with one of the four following conditions: aortic stenosis, atrial septal defect secundum, coarctation of the aorta, and complex dextrocardia. Two-hundred nineteen probands meeting the criteria of the study, which excluded known malformation syndromes, were identified by searching the cardiologic records of the General and Sick Children’s Hospitals in Toronto and subsequent tracing of subjects.
KeywordsCongenital Heart Disease Aortic Stenosis Atrial Septal Defect Recurrence Risk Congenital Heart Defect
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