A High Risk of Heart Defects among the Offspring of Parents Affected with Four Types of Congenital Heart Disease

  • Vera Rose
  • Reynold M. J. Gold
  • Gail Lindsay
Conference paper


We have examined the incidence of congenital heart disease among offspring of parents with one of the four following conditions: aortic stenosis, atrial septal defect secundum, coarctation of the aorta, and complex dextrocardia. Two-hundred nineteen probands meeting the criteria of the study, which excluded known malformation syndromes, were identified by searching the cardiologic records of the General and Sick Children’s Hospitals in Toronto and subsequent tracing of subjects.


Congenital Heart Disease Aortic Stenosis Atrial Septal Defect Recurrence Risk Congenital Heart Defect 
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  1. 1.
    Whittemore R, Hobbins JC, Engle MA: Pregnancy and its outcome in women with and without surgical treatment of congenital heart disease. Am J Cardiol 50: 641–651, 1982.PubMedCrossRefGoogle Scholar
  2. 2.
    Carter CO: The inheritance of common congenital malformations. Progr Med Genet 4: 59–84, 1965.Google Scholar
  3. 3.
    Nora JJ, Nora AH: Recurrence risks in children having one parent with a congenital heart disease. Circulation 53: 701–702, 1976.PubMedCrossRefGoogle Scholar
  4. 4.
    Nora JJ, Nora AH: The evolution of specific genetic and environmental counseling in congenital heart disease. Circulation 57: 205–213, 1978.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1986

Authors and Affiliations

  • Vera Rose
  • Reynold M. J. Gold
  • Gail Lindsay

There are no affiliations available

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