Abnormal Diastolic Function after Kawasaki Disease: A Radionuclide Assessment

  • Linda J. Addonizio
  • Lynne Johnson
  • Jerry Jacobs
  • Welton M. Gersony
Conference paper


Kawasaki disease (KD) is an acute febrile illness of unknown etiology that is characterized by a generalized microvasculitis that can result in coronary artery aneurysms. Coronary aneurysms are reported to occur in up to 25% of patients, and mortality in this disease is related to complications of these aneurysms [1, 2]. Systolic ventricular dysfunction secondary to coronary aneurysms and/or stenosis in KD has been reported. However, the great majority of patients usually have a normal electrocardiogram (ECG) and/or twovdimensional echocardiograms (2-D echo). In adults with coronary disease, left ventricular diastolic dysfunction has been found to be a more sensitive indicator of myocardial abnormalities than systolic parameters [3]. Therefore, the purpose of this study was to evaluate systolic and diastolic ventricular function in children post-KD by means of radionuclide techniques.


Kawasaki Disease Coronary Artery Aneurysm Kawasaki Disease Patient Diastolic Ventricular Function Ventricular Diastolic Dysfunction 
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  1. 1.
    Hiraishi S, Yashiro K, et al: Clinical course of cardiovascular involvement in the mucocutaneous lymph node syndrome. Am J Cardiol47: 323, 1981.PubMedCrossRefGoogle Scholar
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    Fujinara H, Hamashima Y: Pathology of the heart in Kawasaki disease. Pediatrics61: 100, 1978.Google Scholar
  3. 3.
    Borrow RO, Bacharach S, et al: Impaired left ventricular diastolic filling in patients with coronary artery disease. Assessment with radionuclide angiography. Circulation64: 315, 1981.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1986

Authors and Affiliations

  • Linda J. Addonizio
  • Lynne Johnson
  • Jerry Jacobs
  • Welton M. Gersony

There are no affiliations available

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