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Abnormal Diastolic Function after Kawasaki Disease: A Radionuclide Assessment

  • Linda J. Addonizio
  • Lynne Johnson
  • Jerry Jacobs
  • Welton M. Gersony
Conference paper

Abstract

Kawasaki disease (KD) is an acute febrile illness of unknown etiology that is characterized by a generalized microvasculitis that can result in coronary artery aneurysms. Coronary aneurysms are reported to occur in up to 25% of patients, and mortality in this disease is related to complications of these aneurysms [1, 2]. Systolic ventricular dysfunction secondary to coronary aneurysms and/or stenosis in KD has been reported. However, the great majority of patients usually have a normal electrocardiogram (ECG) and/or twovdimensional echocardiograms (2-D echo). In adults with coronary disease, left ventricular diastolic dysfunction has been found to be a more sensitive indicator of myocardial abnormalities than systolic parameters [3]. Therefore, the purpose of this study was to evaluate systolic and diastolic ventricular function in children post-KD by means of radionuclide techniques.

Keywords

Kawasaki Disease Coronary Artery Aneurysm Kawasaki Disease Patient Diastolic Ventricular Function Ventricular Diastolic Dysfunction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Hiraishi S, Yashiro K, et al: Clinical course of cardiovascular involvement in the mucocutaneous lymph node syndrome. Am J Cardiol47: 323, 1981.PubMedCrossRefGoogle Scholar
  2. 2.
    Fujinara H, Hamashima Y: Pathology of the heart in Kawasaki disease. Pediatrics61: 100, 1978.Google Scholar
  3. 3.
    Borrow RO, Bacharach S, et al: Impaired left ventricular diastolic filling in patients with coronary artery disease. Assessment with radionuclide angiography. Circulation64: 315, 1981.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1986

Authors and Affiliations

  • Linda J. Addonizio
  • Lynne Johnson
  • Jerry Jacobs
  • Welton M. Gersony

There are no affiliations available

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