Specific Membrane Lectin of Human T Suppressor Cells

  • Claudine Kieda
  • Michel Monsigny
Conference paper

Abstract

Membrane lectins on murine lymphocytes have previously been described (1,2). They are sugar-specific receptors distributed on subpopulations of cells. Their presence has also been investigated on human peripheral blood leukocytes (3,4), where they are also distributed on distinct subpopulations. Furthermore, it could be shown that a suppressive effect on B cell immunoglobulin production can be inhibited by α-L-rhamnosyl derivatives (4–6).

Keywords

Sugar Albumin Adduct Fractionation Dium 

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References

  1. 1.
    Kieda, C.M., D.J. Bowles, A. Ravid, and N. Sharon. 1978. Lectins in lymphocytes membranes. FEBS Lett. 94: 391.PubMedCrossRefGoogle Scholar
  2. 2.
    Kieda, C.M., A.C. Roche, F. Delmotte, and M. Monsigny. 1979. Lymphocytes membrane lectins: Direct visualization by the use of fluorescent glycosylated cytochemical markers. FEBS Lett. 99: 329.PubMedCrossRefGoogle Scholar
  3. 3.
    Barzilay, M., M. Monsigny, and N. Sharon. 1982. Interaction of soybean agglutinin with human peripheral blood lymphocytes subpopulations: evidence for the existence of a lectin-like substance on the lymphocyte surface. In: Lectins: Biology, biochemistry and clinical biochemistry, Vol. 2, T.C. Bog-Hansen, ed. W. de Gruyter, Berlin, New York, pp. 67–81.Google Scholar
  4. 4.
    Kieda, C.M., M. Monsigny, and M.J. Waxdal. 1982. Endogenous lectins on human peripheral blood lymphocytes. In: Lectins: Biology, biochemistry and clinical biochemistry, Vol. 3, T.C. Bog-Hansen and G.A. Spengler, eds. W. de Gruyter, Berlin, pp. 427–433.Google Scholar
  5. 5.
    Fleisher, T.A., W.C. Greene, R.M. Blaese, and T.A. Waldmann. 1981. Soluble suppressor supernatants elaborated by Concanavalin A activated human mononuclear cells. 1. Characterization of a soluble suppressor of T cells proliferation. J. Immunol. 126: 1192.PubMedGoogle Scholar
  6. 6.
    Greene, W.C., T.A. Fleisher, and T.A. Waldmann. 1981. Soluble suppressor supernatants elaborated by Concanavalin A activated human mononuclear cells. 2. Characterization of a soluble suppressor of B cells immunoglobulin production. J. Immunol. 126: 1158.Google Scholar
  7. 7.
    Monsigny, M., C.M. Kieda, and A.C. Roche. 1983. Membrane glycoproteins, glycolipids and membrane lectins as recognition signals in normal and malignant cells. Biol. Cell. 47: 95.Google Scholar
  8. 8.
    Boyum, A. 1968. Isolation of mononuclear cells and granulocytes from human blood. Scand. J. Clin. Lab. Invest. 21: 1.Google Scholar
  9. 9.
    Bentwich, Z., S.D. Douglas, F.D. Siegal, and H.G. Kunkel. 1973. The formation of stable E rosettes after neuraminidase treatment of either human peripheral blood lymphocytes or sheep red blood cells. Clin. Immunol. Immunopathol. 1: 511.Google Scholar
  10. 10.
    Koski, I.R., D.G. Poplack, and R.M. Blaese. 1976. A non specific esterase stain for the identification of monocytes and macrophages. In: In vitro methods in cell mediated and tumor immunity, B.R. Bloom and J.R. David, eds. Academic Press, New York, pp. 359–362.Google Scholar
  11. 11.
    Johnson, G.D., E.J. Holborow, and J. Dorling. 1978 Immunofluorescence and immunoenzyme techniques. In: Handbook of experimental immunology, D.M. Weir ed. Blackwell Scientific, Oxford, pp. 15.1–15.30.Google Scholar
  12. 12.
    Kieda, C.M., M.J. Waxdal, and M. Monsigny. Involvement of membrane glycoconjugates and membrane lectins in lymphocytes homing. J. Immunol. (submitted).Google Scholar
  13. 13.
    Gronowicz, E., A. Coutinho and F. Melchers. 1976. A plaque assay for all cells secreting immunoglobulin of a given type or class. Eur. J. Immunol. 6: 588.PubMedCrossRefGoogle Scholar
  14. 14.
    Ginsburg, W.W., F.D. Finkelman, and P.E. Lipsky. 1978. Circulating and mitogen-induced immunoglobulin secreting cells in human peripheral blood: evaluation by a reverse hemolytic plaque assay. J. Immunol. 120: 33.PubMedGoogle Scholar

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© Springer-Verlag New York Inc. 1986

Authors and Affiliations

  • Claudine Kieda
  • Michel Monsigny

There are no affiliations available

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