Specific Membrane Lectin of Human T Suppressor Cells
Membrane lectins on murine lymphocytes have previously been described (1,2). They are sugar-specific receptors distributed on subpopulations of cells. Their presence has also been investigated on human peripheral blood leukocytes (3,4), where they are also distributed on distinct subpopulations. Furthermore, it could be shown that a suppressive effect on B cell immunoglobulin production can be inhibited by α-L-rhamnosyl derivatives (4–6).
KeywordsSugar Albumin Adduct Fractionation Dium
Unable to display preview. Download preview PDF.
- 3.Barzilay, M., M. Monsigny, and N. Sharon. 1982. Interaction of soybean agglutinin with human peripheral blood lymphocytes subpopulations: evidence for the existence of a lectin-like substance on the lymphocyte surface. In: Lectins: Biology, biochemistry and clinical biochemistry, Vol. 2, T.C. Bog-Hansen, ed. W. de Gruyter, Berlin, New York, pp. 67–81.Google Scholar
- 4.Kieda, C.M., M. Monsigny, and M.J. Waxdal. 1982. Endogenous lectins on human peripheral blood lymphocytes. In: Lectins: Biology, biochemistry and clinical biochemistry, Vol. 3, T.C. Bog-Hansen and G.A. Spengler, eds. W. de Gruyter, Berlin, pp. 427–433.Google Scholar
- 6.Greene, W.C., T.A. Fleisher, and T.A. Waldmann. 1981. Soluble suppressor supernatants elaborated by Concanavalin A activated human mononuclear cells. 2. Characterization of a soluble suppressor of B cells immunoglobulin production. J. Immunol. 126: 1158.Google Scholar
- 7.Monsigny, M., C.M. Kieda, and A.C. Roche. 1983. Membrane glycoproteins, glycolipids and membrane lectins as recognition signals in normal and malignant cells. Biol. Cell. 47: 95.Google Scholar
- 8.Boyum, A. 1968. Isolation of mononuclear cells and granulocytes from human blood. Scand. J. Clin. Lab. Invest. 21: 1.Google Scholar
- 9.Bentwich, Z., S.D. Douglas, F.D. Siegal, and H.G. Kunkel. 1973. The formation of stable E rosettes after neuraminidase treatment of either human peripheral blood lymphocytes or sheep red blood cells. Clin. Immunol. Immunopathol. 1: 511.Google Scholar
- 10.Koski, I.R., D.G. Poplack, and R.M. Blaese. 1976. A non specific esterase stain for the identification of monocytes and macrophages. In: In vitro methods in cell mediated and tumor immunity, B.R. Bloom and J.R. David, eds. Academic Press, New York, pp. 359–362.Google Scholar
- 11.Johnson, G.D., E.J. Holborow, and J. Dorling. 1978 Immunofluorescence and immunoenzyme techniques. In: Handbook of experimental immunology, D.M. Weir ed. Blackwell Scientific, Oxford, pp. 15.1–15.30.Google Scholar
- 12.Kieda, C.M., M.J. Waxdal, and M. Monsigny. Involvement of membrane glycoconjugates and membrane lectins in lymphocytes homing. J. Immunol. (submitted).Google Scholar