Abstract
The first cluster of differentiation, CD1 [Thy, gp45, 12], defined by the First International Workshop on Human Leucocyte Differentiation Antigens (1) included antibodies NA1/34, T6, D47, and M241. The antibodies reacted with thymocytes, but not peripheral T cells, with some T-ALL cells from both children and adults, and with some T-lymphoid cell lines. Antibodies D47 (2) and M241 (3) particularly were dissociated from NA1/34 (4) and T6 (5) in, respectively, T-ALL cells from adults and T-ALL cells from children. Biochemically all of the CD1 antibodies recognize a structure which is similar to that of human HLA-class I molecules with approximately 45,000-M r heavy chains attached to β2-microglobulin.
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Boumsell, L., Amiot, M., Raynal, B., Gay-Bellile, V., Caillou, B., Bernard, A. (1986). Epitopic Groups of CD1 Molecules. In: Reinherz, E.L., Haynes, B.F., Nadler, L.M., Bernstein, I.D. (eds) Leukocyte Typing II. Springer, New York, NY. https://doi.org/10.1007/978-1-4613-8587-5_23
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DOI: https://doi.org/10.1007/978-1-4613-8587-5_23
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