Epitopic Groups of CD1 Molecules

  • Laurence Boumsell
  • Martine Amiot
  • Brigitte Raynal
  • Véronique Gay-Bellile
  • Bernard Caillou
  • Alain Bernard


The first cluster of differentiation, CD1 [Thy, gp45, 12], defined by the First International Workshop on Human Leucocyte Differentiation Antigens (1) included antibodies NA1/34, T6, D47, and M241. The antibodies reacted with thymocytes, but not peripheral T cells, with some T-ALL cells from both children and adults, and with some T-lymphoid cell lines. Antibodies D47 (2) and M241 (3) particularly were dissociated from NA1/34 (4) and T6 (5) in, respectively, T-ALL cells from adults and T-ALL cells from children. Biochemically all of the CD1 antibodies recognize a structure which is similar to that of human HLA-class I molecules with approximately 45,000-M r heavy chains attached to β2-microglobulin.


Eccrine Sweat Gland Thymus Cell Percent Positive Cell Epitopic Group Human Leukocyte Differentiation Antigen 
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© Springer-Verlag New York Inc. 1986

Authors and Affiliations

  • Laurence Boumsell
  • Martine Amiot
  • Brigitte Raynal
  • Véronique Gay-Bellile
  • Bernard Caillou
  • Alain Bernard

There are no affiliations available

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