Abstract
A variety of human T cell surface antigens have been discovered through the use of monoclonal antibodies (mAbs) (1). Some of them have been postulated to play important roles in immunoregulation. T8 (Leu-2) and T4 (Leu-3) antigens, for example, which were originally thought to be suppressor/cytotoxic and helper/inducer T cell markers, respectively, have been analyzed in detail and the results indicate that T8 and T4 antigens serve as receptors for class I and class II major histocompatibility complex (MHC) antigens, respectively (2–4).
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Takei, T., Ishii, Y., Kon, S., Fujimoto, J., Kikuchi, K. (1986). Determinant Heterogeneity of CD5, CD8, and CD4 Antigen Molecules as Defined by Monoclonal Antibodies. In: Reinherz, E.L., Haynes, B.F., Nadler, L.M., Bernstein, I.D. (eds) Leukocyte Typing II. Springer, New York, NY. https://doi.org/10.1007/978-1-4613-8587-5_21
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DOI: https://doi.org/10.1007/978-1-4613-8587-5_21
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