• H. E. Völcker
  • G. O. H. Naumann


The vitreous is the transparent gel which occupies almost the entire space between the lens and retina; it represents about two-thirds of the volume of the eye. Ninety-nine percent of the vitreous is water bound with collagen and hyaluronic acid. This forms a hydrogel with high viscosity. The vitreous substance, in conjunction with the aqueous of the anterior segment, is responsible for maintenance of the spherical form of the globe. In addition, the pressure of the vitreous on the retinal surface provides protection against retinal detachment.


Retinal Detachment Optic Nerve Head Posterior Vitreous Detachment Ciliary Process Vitreous Opacity 
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  1. 1.
    Anderson R, Kassman T: Vitreous opacities in primary familial amyloidosis. Acta Ophthalmol (Copenh) 46:441, 1968CrossRefGoogle Scholar
  2. 2.
    Balacz EA: Molecular morphology of the vitreous body. In: Smelser GK (ed): Structure of the Eye, p. 293. Academic Press, New York, 1961Google Scholar
  3. 3.
    Balacz EA: The molecular biology of the vitreous. In: McPherson A (ed): New and Controversial Aspects of Retinal Detachment, p. 3. Harper & Row, New York, 1968Google Scholar
  4. 4.
    Bard LA: Asteroidhyalitis: relationship to diabetes and hypercholesterolemia. Am J Ophthalmol 58:239, 1964PubMedGoogle Scholar
  5. 5.
    Bellhorn MB, Friedman AH, Wise GN, Hen-kind P: Ultrastructure and clinicopathologic correlation of idiopathic preretinal macular fibrosis. Am J Ophthalmol 79:366, 1975PubMedGoogle Scholar
  6. 6.
    Benson AH: Diseases of the vitreous. Trans Ophtholmol Soc UK 14:101, 1894Google Scholar
  7. 7.
    Benson WE, Spalter HF: Vitreous hemorrhage: a review of experimental and clinical investigations. Surv Ophthalmol 15:297, 1971Google Scholar
  8. 8.
    Blodi FC: Preretinal glial nodules in persistance and hyperplasia of primary vitreous. Arch Ophthalmol 87:531, 1972PubMedGoogle Scholar
  9. 9.
    Böhringer HR, Dieterle P, Landolt E: Zur Klinik und Pathologie der Degeneratio hyaloideoretinalis hereditaria (Wagner). Ophthalmologica 139:330, 1960CrossRefGoogle Scholar
  10. 10.
    Brucker AJ, Fine S, Michels RG: Congenital retinal arterial loops and vitreous hemorrhage. Am J Ophthalmol 84:220, 1977PubMedGoogle Scholar
  11. 11.
    Coulombre AJ, Steinberg SN, Coulombre JL: The role of intraocular pressure in the development of the chick eye. Invest Ophthalmol 2:83, 1963PubMedGoogle Scholar
  12. 12.
    Crawford JB: Cotton-wool-exudates in systemic amyloidosis. Arch Ophthalmol 78:214, 1967PubMedGoogle Scholar
  13. 13.
    Criswick VG, Schepens CL: Familial exudative vitreoretinopathy. Am J Ophthalmol 68:578, 1969PubMedGoogle Scholar
  14. 14a.
    Eickhoff W: Pseudophakia lentis fibromatosa sive pseudolipomatosa. Klin Monatsbl Augen-heilkd 132:525, 1958Google Scholar
  15. 14b.
    Engel H, de la Cruz ZC, Jimenez-Abaluhin BS, et al: Cytopreparatory techniques for eye fluid specimens obtained by vitrectomy. Acta Cytol 26:551, 1982PubMedGoogle Scholar
  16. 14c.
    Engel HM, Green WR, Michels RG, et al: Diagnostic vitrectomy. Retina 1:121, 1981PubMedCrossRefGoogle Scholar
  17. 14d.
    Eversbusch O: Ein bemerkenswerter Fall von Sichtbarkeit der Ciliarfortsätze im Pupillargebiet. Mün Med Wschr 48:1, 1901Google Scholar
  18. 15.
    Fanta H: Die Glaskörperabhebung nach indirektem Trauma. Graefes Arch Ophthalmol 146:684, 1944CrossRefGoogle Scholar
  19. 16a.
    Fanta H: Veränderungen des Glaskörpers im höheren Lebensalter (Lakunenbildung, Glaskörperabhebung). Klin Monatsbl Augenheilkd 165:76, 1974PubMedGoogle Scholar
  20. 16b.
    Faulborn J, Bowald S: Combined macroscopic, light microscopic, scanning, and transmission electron microscopic investigation of the vitreous body. The structure of the anterior border layer of the vitreous. Ophthal Res 15:11, 1983Google Scholar
  21. 17.
    Favre M: A propos de deux cas de dégénérescence hyaloidéorétinienne. Ophthalmologica 135:604, 1958PubMedCrossRefGoogle Scholar
  22. 18.
    Favre M, Goldmann H: Zur Genese der hinteren Glaskörperabhebung. Ophthalmologica 132:87, 1956PubMedCrossRefGoogle Scholar
  23. 19.
    Ferry AP, Lieberman ThW: Bilateral amyloidosis of the vitreous body. Arch Ophthalmol 94:982, 1976PubMedGoogle Scholar
  24. 20.
    Fine BS, Tousimis AI: The structure of the vitreous body and the suspensory ligaments of the lens. Arch Ophthalmol 65:95, 1961PubMedGoogle Scholar
  25. 21.
    Font RL, Yanoff M, Zimmerman LE: Intraocular adipose tissue and persistent hyperplastic primary vitreous. Arch Ophthalmol 82:43, 1969PubMedGoogle Scholar
  26. 22.
    Foos RY: Anatomic and pathologic aspects of the vitreous body. Trans Am Acad Ophthalmol Otolaryngol 77:171, 1973Google Scholar
  27. 23.
    Foos RY: Vitreoretinal juncture; epiretinal membranes and vitreous. Invest Ophthalmol 16:416, 1977Google Scholar
  28. 24.
    Foos RY, Gloor BP: Vitreoretinal juncture: healing of experimental wounds. Graefes Arch Klin Exp Ophthalmol 196:213, 1975CrossRefGoogle Scholar
  29. 25.
    Foos RY, Roth AM: Surface structure of the optic nerve head. II. Vitreopapillary attachments and posterior vitreous detachments. Am J Ophthalmol 76:662, 1973PubMedGoogle Scholar
  30. 26a.
    Forsius H: Cholesterol crystals in the anterior chamber. Acta Ophthalmol (Copenh) 39:284, 1961CrossRefGoogle Scholar
  31. 26b.
    Forrester JV, Grierson I, Lee WR: The pathology of vitreous hemorrhage. II. Ultrastructure. Arch Ophthalmol 97:2368, 1979PubMedGoogle Scholar
  32. 27.
    Gass JDM: Surgical excision of persistent hyperplastic primary vitreous. Arch Ophthalmol 83:163, 1970PubMedGoogle Scholar
  33. 28.
    Gloor B: Biomicroscopy of the vitreous and of vitreoretinal pathology. In: Becker B, Burde R (eds): Current Concepts in Ophthalmology, pp. 49–76. Mosby, St. Louis, 1969Google Scholar
  34. 29.
    Gloor B: On the question of the origin of macrophages in the retina and the vitreous following photocoagulation (autoradiographic investigation by means of 3H-thymidine). Graefes Arch Klin Exp Ophthalmol 190:183, 1974CrossRefGoogle Scholar
  35. 30.
    Gloor B: Persistierender hyperplastischer primärer Glaskörper. Klin Monatsbl Augenheilkd 166:293, 1975Google Scholar
  36. 31.
    Gloor B: Mitotic activity in the cortical vitreous cells (hyalocytes) after photocoagulation. Invest Ophthalmol 8:633, 1969PubMedGoogle Scholar
  37. 32.
    Gloor BP: Phagocytoide Aktivität des Pigmentepithels nach Lichtkoagulation (zur Frage der Herkunft von Makrophagen in der Retina). Graefes Arch Klin Exp Ophthalmol 179:105, 1969CrossRefGoogle Scholar
  38. 33.
    Gloor B: Physiology of the vitreous. In: Adler F, Moses R (eds): Physiology of the Eye. ed. 5, pp. 311–332. Mosby, St. Louis, 1970Google Scholar
  39. 34.
    Gloor B: Zur Entwicklung des Glaskörpers und der Zonula. I. Überblick und chronologischer Ablauf der Glaskörper- und Zonulaentwicklung bei Kaninchen und Maus. Graefes Arch Klin Exp Ophthalmol 186:299, 1973CrossRefGoogle Scholar
  40. 35.
    Gloor B: Zur Entwicklung des Glaskörpers und der Zonula. IL Glaskörperzellen während Entwicklung und Rückbildung der Vasa hyaloidea und der Tunica vasculosa lentis. Graefes Arch Klin Exp Ophthalmol 186:311, 1973CrossRefGoogle Scholar
  41. 36.
    Gloor B: Zur Entwicklung des Glaskörpers und der Zonula. III. Herkunft, Lebenszeit und Ersatz der Glaskörperzellen beim Kaninchen (autoradiographische Untersuchungen mit 3H-Thymidin). Graefes Arch Klin Exp Ophthalmol 187:21, 1973CrossRefGoogle Scholar
  42. 37.
    Gloor B: Zur Entwicklung des Glaskörpers und der Zonula. IV. Beziehungen zwischen der Zonula, den Vasa hyaloidea und der Tunica vasculosa lentis. Graefes Arch Klin Exp Ophthalmol 187:45, 1973CrossRefGoogle Scholar
  43. 38.
    Gloor B: Zur Entwicklung des Glaskörpers und der Zonula. V. Zur Entwicklung der Netzhaut-gefässe des Kaninchens. Graefes Arch Klin Exp Ophthalmol 187:147, 1973CrossRefGoogle Scholar
  44. 39.
    Gloor B: Zur Entwicklung des Glaskörpers und der Zonula. VI. Autoradiographische Untersuchungen zur Entwicklung der Zonula der Maus mit 3H-markierten Aminosäuren und 3H-Thymidin. Graefes Arch Klin Exp Ophthalmol 189:105, 1974CrossRefGoogle Scholar
  45. 40.
    Gloor B, Daicker B: Pathology of the vitreoretinal border structures. Trans Ophthalmol Soc UK 95:387, 1975PubMedGoogle Scholar
  46. 41.
    Gloor B, Werner H: Postkoagulative und spontan auftretende internoretinale Fibroplasie mit Maculadegeneration. Klin Monatsbl Augenheilkd 151:822, 1967PubMedGoogle Scholar
  47. 42.
    Goldmann H: Biomikroskopie des normalen menschlichen Glaskörpers während des Lebens. Ber Tag Dtsch Ophthalmol Ges 68:15, 1967Google Scholar
  48. 43.
    Goldstein S: The biology of aging. N Engl J Med 285:1120, 1971PubMedCrossRefGoogle Scholar
  49. 44.
    Gow J, Oliver GL: Familial exudative vitreoretinopathy. Arch Ophthalmol 86:150, 1971PubMedGoogle Scholar
  50. 45.
    Greeff R: Glaskörper (Corpus vitreum). In: Henke F, Lubarsch O (eds): Handbuch der speziellen pathologischen Anatomie und Histologie, Vol. XI, ed. 1, p. 819. Springer, Berlin, 1928Google Scholar
  51. 46.
    Haddad R, Font RL, Reeser F: Persistent hyperplastic primary vitreous: a clinicopathologic study of 62 cases and review of the literature. Surv Ophthalmol 23:123, 1978PubMedCrossRefGoogle Scholar
  52. 47.
    Hamburg A: Unusual cause of vitreous opacities: primary familial amyloidosis. Ophthalmologic 162:173, 1971CrossRefGoogle Scholar
  53. 48.
    Harley RD: Pediatric Ophthalmology. Philadelphia, Saunders, 1975Google Scholar
  54. 49.
    Hatfield RE, Gastineau CF, Rucker SW: Asteroid bodies in the vitreous: relationship to diabetes and hypercholesterolemia. Proc Mayo Clin 37:513, 1962Google Scholar
  55. 50.
    Heydenreich A: Zur Pathogenese des Pseudoglioms. Klin Monatsbl Augenheilkd 134:465, 1959Google Scholar
  56. 51.
    Hirose T, Lee KY, Schepens CL: Wagner’s hereditary vitreoretinal degeneration and retinal detachment. Arch Ophthalmol 89:176, 1973PubMedGoogle Scholar
  57. 52.
    Hitchings RA, Tripathi RC: Vitreous opacities in primary amyloid disease—a clinical, histochemical and ultrastructural report. Br J Ophthalmol 60:41, 1976PubMedCrossRefGoogle Scholar
  58. 53.
    Hruby K: Erkrankungen des Glaskörpers. In: Velhagen K (ed): Der Augenarzt, p. 1111. Thieme, Stuttgart, 1960Google Scholar
  59. 54.
    Inomata H: Woundhealing after xenon-arc photocoagulation in the rabbit retina. Ophthalmologica 170:462, 1975PubMedCrossRefGoogle Scholar
  60. 55.
    Jaeger W (ed): Der Glaskörper. Ber Dtsch Ophthalmol Ges 68:1, 1967Google Scholar
  61. 56.
    Jaffe NS: The Vitreous in Clinical Ophthalmology. Mosby, St. Louis, 1969Google Scholar
  62. 57.
    Jensen OA: Persistant hyperplastic primary vitreous. Acta Ophthalmol (Copenh) 46:418, 1968CrossRefGoogle Scholar
  63. 58.
    Jess A: Der Glaskörper und seine Erkrankungen. In: von F. Schieck - PA Brückner (ed): Kurzes Handbuch der Ophthalmologie, Vol. 5, p. 325. Springer, Berlin, 1930Google Scholar
  64. 59a.
    Joseph M, Ivry M, Oliver M: Persistent hyperplastic primary vitreous at the optic nerve head. Am J Ophthalmol 73:580, 1973Google Scholar
  65. 59b.
    Kampik A: Klinische und pathologische Aspekte epiretinaler Membranbildungen. Klin Monatsbl Augenheilkd 181:386, 1982PubMedCrossRefGoogle Scholar
  66. 60.
    Laqua H, Machemer R: Clinical-pathological correlation of massive periretinal proliferation. Am J Ophthalmol 80:913, 1975PubMedGoogle Scholar
  67. 61.
    Laqua H, Machemer R: Glial cell proliferations in retinal detachment (massive periretinal proliferation). Am J Ophthalmol 80:602, 1975PubMedGoogle Scholar
  68. 62.
    Lerche W, Wulle KG: Zur Feinstruktur des embryonalen menschlichen Glaskörpers unter besonderer Berücksichtigung seiner Beziehung zu Linse und Retina. Ber Dtsch Ophthalmol Ges 68:82, 1967Google Scholar
  69. 63.
    Mandelcorn MS, Machemer R, Fineberg E, Hersch SB: Proliferation and metaplasia of intravitreal retinal pigmentepithelium cell auto-transplants. Am J Ophthalmol 80:227, 1975PubMedGoogle Scholar
  70. 64.
    Mann I: Developmental Abnormalities of the Eye. Lippincott, Philadelphia, 1937Google Scholar
  71. 65.
    Mann I: The nature and boundaries of the vitreous. Trans Ophthalmol Soc UK 47:172, 1927Google Scholar
  72. 66.
    Manschot WA: Pathology of hereditary conditions related to retinal detachment. Ophthalmologca 162:223, 1971CrossRefGoogle Scholar
  73. 67.
    Manschot W: Pathology of hereditary juvenile retinoschisis. Arch Ophthalmol 88:131, 1972PubMedGoogle Scholar
  74. 68.
    Manschot WA: Persistent hyperplastic primary vitreous. Arch Ophthalmol 59:188, 1958Google Scholar
  75. 69.
    Manschot WA: Synchisis scintillans. Acta Ophthalmol (Copenh) 20:80, 1942CrossRefGoogle Scholar
  76. 70.
    March W, Schoch D, O’Grady R: Composition of asteroid bodies. Invest Ophthalmol 13:699, 1974Google Scholar
  77. 71.
    Nankin S, Scott W: Persistent hyperplastic primary vitreous. Arch Ophthalmol 95:240, 1977PubMedGoogle Scholar
  78. 72.
    Paton D, Duke JR: Primary familial amyloidosis. Am J Ophthalmol 61:736, 1966PubMedGoogle Scholar
  79. 73.
    Pau H: Ätiologische Betrachtung zur Scintillatio nivea. Ophthalmologica 150:167, 1965PubMedCrossRefGoogle Scholar
  80. 74.
    Pau H: Die Strukturen des Glaskörpers in Beziehung zu embryonalen Blutgefässen und Glaskörperrindenzellen. Graefes Arch Klin Exp Ophthalmol 177:261, 1969CrossRefGoogle Scholar
  81. 75.
    Pau H: Physiologische Chemie des Auges. In: Velhagen K (ed): Der Augenarzt, p. 363. Thieme, Stuttgart, 1958Google Scholar
  82. 76.
    Pietruschka G: Zur Ätiologie und Therapie von Glaskörpereinblutungen. Klin Monatsbl Augenheilkd 144:641, 1964PubMedGoogle Scholar
  83. 77.
    Pruett RC: The pleomorphism and complications of the posterior hyperplastic primary vitreous. Am J Ophthalmol 80:625, 1975PubMedGoogle Scholar
  84. 78.
    Pruett RC, Schepens CL: Posterior hyperplastic primary vitreous. Am J Ophthalmol 69:535, 1970Google Scholar
  85. 79.
    Reese AB: Persistent hyperplastic primary vitreous (Jackson memorial lecture). Am J Ophthalmol 40:317, 1955PubMedGoogle Scholar
  86. 80.
    Reese AB, Jones IS, Cooper WC: Macular changes secondary to vitreous traction. Trans Am Ophthalmol Soc 64:123, 1966PubMedGoogle Scholar
  87. 81.
    Rentsch FJ: Preretinal proliferation of glia-cells after mechanical injuries of the rabbit retina. Graefes Arch Klin Exp Ophthalmol 188:79, 1973CrossRefGoogle Scholar
  88. 82a.
    Rentsch FJ: The Ultrastructure of the Vitreous and of the Vitreoretinal Border Layers in Man. Thieme, Stuttgart, 1979Google Scholar
  89. 82b.
    Rentsch FJ: The Retina Society Terminology Committee: Classification of Retinal Detachment with Proliferative Vitredretinopathy. Ophthalmology 90:121,1983Google Scholar
  90. 83.
    Rieger H: Erbpathologie des Auges. In: Velhagen K (ed): Der Augenarzt. Thieme, Stuttgart, 1958Google Scholar
  91. 84.
    Rodman HI, Johnson SBA, Zimmerman LE: New histopathological and histochemical observations concerned with asteroid hyalitis. Arch Ophthalmol 66:552, 1961PubMedGoogle Scholar
  92. 85.
    Roth AM, Foos RY: Surface structure of the optic nerve head. I. Epipapillary membranes. Am J Ophthalmol 74:977, 1972Google Scholar
  93. 86.
    Roth AM, Foos RY: Surface wrinkling retinopathy in eyes enucleated at autopsy. Trans Am Acad Ophthalmol Otolaryngol 75:1047, 1971PubMedGoogle Scholar
  94. 87.
    Schepens CL: Present-day treatment of retinoschisis: an evaluation. In: McPherson A (ed): New and Controversial Aspects of Retinal Detachment, p. 438. Harper & Row, New York, 1968Google Scholar
  95. 88.
    Schepens CL: Clinical aspects of pathologic changes in the vitreous body. Am J Ophthalmol 38:8, 1954PubMedGoogle Scholar
  96. 89.
    Schreck E: Glaskörper. Almanach Augenheilk, Munich 1960Google Scholar
  97. 90a.
    Schroeder W: Nutzen der A-Bildechographie in der klinischen Diagnostik des peristierenden hyperplastischen primären Glaskörpers. Klin Monatsbl Augenheilkd 168:210, 1976PubMedGoogle Scholar
  98. 90b.
    Schwanz MF, Green WR, Michels RG: An unusual case of ocular involvement in primary systemic nonfamilial amyloidosis. Ophthalmology 89:394, 1982Google Scholar
  99. 91.
    Selm J van: Surgery for retinal dysplasia and hyperplasia of the persistent primary vitreous. Trans Ophthalmol Soc UK 89:545, 1969Google Scholar
  100. 92.
    Sheehan B: Congenital vascular veils in the vitreous. Trans Ophthalmol Soc UK 72:623, 1952Google Scholar
  101. 93.
    Smith JL: Asteroidhyalitis: incidence of diabetes mellitus and hypercholesterolemia. JAMA 168:891, 1958Google Scholar
  102. 94.
    Smith RE, Maumenee AE: Persistent hyperplastic primary vitreous: results of surgery. Trans Am Acad Ophthalmol Otolaryngol 78:911, 1974Google Scholar
  103. 95.
    Spaulding A: Persistent hyperplastic primary vitreous humor: a finding in a 71-year-old man. Surv Ophthalmol 12:448, 1968Google Scholar
  104. 96.
    Spaulding AG, Naumann GOH: Persistent hyperplastic primary vitreous in an adult: a brief review of the literature and histopathologic study. Arch Ophthalmol 77:666, 1967PubMedGoogle Scholar
  105. 97.
    Spitznas M: The fine structure of the chorioretinal border tissues of the adult human eye. Adv Ophthalmol 28:78, 1974PubMedGoogle Scholar
  106. 98.
    Spitznas M, Leuenberger R: Die primäre epiretinale Gliose. Klin Monatsbl Augenheilkd 171:410, 1977PubMedGoogle Scholar
  107. 99.
    Tasman W: Posterior vitreous detachment and peripheral retinal breaks. Trans Am Acad Ophthalmol Otolaryngol 72:217, 1968PubMedGoogle Scholar
  108. 100.
    Tolentino FI, Schepens Chi, Freeman HM: Vitreoretinal Disorders—Diagnosis and Management. Saunders, Philadelphia, 1976Google Scholar
  109. 101a.
    Verhoeff FH: Microscopic findings in a case of asteroidhyalitis. Am J Ophthalmol 4:155, 1921Google Scholar
  110. 101b.
    Völcker HE, Lang GK, Naumann GOH: Zur Chirurgie des hinteren Polstars bei persistierendem hyperplastischen primären Glaskörper (PHPV). Klin Monatsbl Augenheilkd 183:79, 1983PubMedCrossRefGoogle Scholar
  111. 102.
    Wagner H: Ein bisher unbekanntes Erbleiden des Auges (Degeneratio hyaloideo-retinalis hereditaria). Beobachtet im Kanton Zürich. Klin Monatsbl Augenheilkd 100:840, 1938Google Scholar
  112. 103.
    Wand MU, Gorn RA: Cholesterolosis of the anterior chamber. Am J Ophthalmol 78:143, 1974PubMedGoogle Scholar
  113. 104.
    Watzke RC: The ophthalmoscopic sign “white with pressure”: a clinicopathologic correlation. Arch Ophthalmol 66:812, 1961PubMedGoogle Scholar
  114. 105.
    Weidenthal DT, Schepens CL: Peripheral fundus changes associated with ocular contusion. Am J Ophthalmol 62:465, 1966PubMedGoogle Scholar
  115. 106.
    Wong VG, McFarlin EE: Primary familial amyloidosis. Arch Ophthalmol 78:208, 1967PubMedGoogle Scholar
  116. 107.
    Yanoff M, Rahn EK, Zimmerman LE: Histopathology of juvenile retinoschisis. Arch Ophthalmol 79:49, 1968PubMedGoogle Scholar
  117. 108.
    Zimmerman LE, Naumann G: Pathology of retinoschisis. In: McPherson A (ed): New and Controversial Aspects of Retinal Detachment, p. 400. Harper & Row, New York, 1968Google Scholar

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  • H. E. Völcker
  • G. O. H. Naumann

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