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Biomechanics Model for Skeletal Muscle Microcirculation with Reference to Red and White Blood Cell Perfusion and Autoregulation

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Cell Mechanics and Cellular Engineering

Abstract

While an expanding body of experimental observations on blood flow in skeletal muscle is accumulating (Granger et al., 1984), few efforts have been made to integrate these data into a unifying picture of the circulation based on microanatomy and properties of microvessel and blood. An analysis is useful since it unifies experimental observations and serves to interpret microvascular hemodynamics in terms of the properties of components that make up the microcirculation. A continuum analysis allows not only to explore the validity of numerous hypothesis but it also is a testing ground for our actual understanding of organ perfusion.

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Authors
  1. S. Lee
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  2. D. Sutton
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  3. M. Fenster
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  4. G. W. Schmid-Schönbein
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Editor information

Editors and Affiliations

  1. Orthopaedic Research Laboratory, Columbia University, 630 W. 168th Street, New York, NY, 10032, USA

    Van C. Mow

  2. Department of Aerospace Engineering, Mechanics and Engineering Science, University of Florida, Gainesville, FL, 32611, USA

    Roger Tran-Son-Tay

  3. Musculo-Skeletal Research Laboratory, Department of Orthopaedics, Health Science Center, State University of New York, Stony Brook, NY, 11794, USA

    Farshid Guilak

  4. Department of Mechanical Engineering and Material Sciences, Duke University, Durham, NC, 27708, USA

    Robert M. Hochmuth

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Lee, S., Sutton, D., Fenster, M., Schmid-Schönbein, G.W. (1994). Biomechanics Model for Skeletal Muscle Microcirculation with Reference to Red and White Blood Cell Perfusion and Autoregulation. In: Mow, V.C., Tran-Son-Tay, R., Guilak, F., Hochmuth, R.M. (eds) Cell Mechanics and Cellular Engineering. Springer, New York, NY. https://doi.org/10.1007/978-1-4613-8425-0_29

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  • DOI: https://doi.org/10.1007/978-1-4613-8425-0_29

  • Publisher Name: Springer, New York, NY

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