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Regulation of Growth Hormone Secretion in Man

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Growth Hormone II

Part of the book series: Serono Symposia USA Norwell, Massachusetts ((SERONOSYMP))

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Abstract

Growth hormone (GH) secretion occurs in a pulsatile fashion because of its primary regulation by two hypothalamic hormones, growth hormone releasing hormone (GHRH) and somatostatin (SRIF). GHRH stimulates GH synthesis; it increases transcription of growth hormone messenger RNA within minutes by increasing cyclic AMP (1). SRIF is probably more important in determining the timing and amplitude of GH pulses, but has no effect on GH synthesis.

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Authors
  1. Mary Lee Vance
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Editor information

Editors and Affiliations

  1. Pediatric Endocrinology, All Children’s Hospital, St. Petersburg, FL, 33701, USA

    Barry B. Bercu M.D.  & Richard F. Walker Ph.D.  & 

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© 1994 Springer-Verlag New York, Inc.

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Vance, M.L. (1994). Regulation of Growth Hormone Secretion in Man. In: Bercu, B.B., Walker, R.F. (eds) Growth Hormone II. Serono Symposia USA Norwell, Massachusetts. Springer, New York, NY. https://doi.org/10.1007/978-1-4613-8372-7_5

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  • DOI: https://doi.org/10.1007/978-1-4613-8372-7_5

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4613-8374-1

  • Online ISBN: 978-1-4613-8372-7

  • eBook Packages: Springer Book Archive

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