Heart Failure Secondary to Coronary Artery Disease

  • Roger M. MillsJr.
  • Carl J. Pepine


In this chapter, we outline our approach to heart failure occurring as a consequence of coronary artery disease. Table 12.1 enumerates the common clinical syndromes of heart failure due to coronary artery disease, the three themes being (a) ischemia with reversible left ventricular (LV) dysfunction, either systolic or diastolic, leading to pulmonary congestion, (b) mechanical complications of infarction, and (c) irreversible myocardial scarring with impairment of LV systolic function leading to low forward cardiac output. The epidemiologic issues involved have been reviewed in prior chapters, but we emphasize again that heart failure represents a major public health problem with more than 400,000 new cases annually in the United States. In the U.S., coronary artery disease is the most common cause of heart failure. Once established, the prognosis with medical management is poor, with an average annual mortality of 30% to 40%.1–3


Heart Failure Coronary Artery Disease Left Ventricu Function Coronary Flow Coronary Flow Reserve 
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© Springer-Verlag New York, Inc. 1994

Authors and Affiliations

  • Roger M. MillsJr.
  • Carl J. Pepine

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