The heart, a hollow, muscular organ about the size of an adult clenched fist, weighs 10 to 12 oz (160 grams) in adult males and 8 to 10 oz in females. It is located in the thoracic cavity in the space between the lungs. Most of the heart lies just to the left of the midline of body (Fig. 15.1). It consists of four chambers: two atria and two ventricles. The atria are thin walled, the ventricles much thicker, particularly the left ventricle, which is the high-pressure chamber.
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