Abstract
Abnormalities in the mobilization of fatty acid during exercise have been described in certain insulin-deficient states, by Issekutz and co-workers (8) as well as by Havel (6) in depancreatized dogs and by Carlström (1, 2) in human diabetes. Present studies were designed to explore the metabolism of endogenous fatty acids in healthy subjects in the prediabetic state, defined according to Cerasi and Luft (4) as a state characterized by poor insulin response to glucose load and normal glucose tolerance.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Carlström, S. & Karlefors, T. Plasma-free-fatty acids during exercise. Lancet i, 331 (1964).
Carlström, S., Studies on fatty acid metabolism in male diabetic patients during exercise. Acta univers. Lund. Sectio II, n:o 20 (1967) (Thesis) C.W.K. Gleerup, Sweden.
Cerasi, E., An analogue computer model for the insulin response to glucose infusion. Acta endoor. (Kbh.) 55, 163 (1963).
Cerasi, E. & Luft, R., “What is inherited-what is added” hypothesis for the pathogenesis of diabetes mellitus. Diabetes 16, 615 (1967).
Hansen, A.P., Abnormal serum growth hormone response to exercise in juvenile diabetics. J. clin, invest. 49, 1467 (1970).
Havel, R., Some influences of the sympathetic nervous system and insulin on mobilization of fat from adipose tissue: Studies on the turnover rates of free fatty acids and glycerol. Ann. N.Y. Acad. Sci., 131, 91 (1965).
Holmgren, A. & Mattsson, K.-H., A new ergometer with constant work load at varying pedalling rate. Scand. J. clin. Lab. invest. 6, 137 (1954).
Iseekutz, B., Miller, H.J. & Rodahl, K., Effect of exercise on FFA-metabolism of pancreatectomized dogs. Am. J. Physiol. 205, 645 (1963).
Sjöstrand, T., Changes in the respiratory organs of workmen at an smelting works. Acta med. scand. 128 (suppl. 196) (1947).
Sutton, J.R., Young, J.D., Lazarus, L., Hickie, J.B. & Maksoytis, J., The hormonal response to physical exercise. Austr. Ann. Med. 18, 84 (1969).
Wahlund, H., Determination of the physical working capacity. Acta med. scand. 132 (suppl. 215) (1948).
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1971 Plenum Press, New York
About this chapter
Cite this chapter
Östman, J., Cerasi, E., Ekelund, LG., Luft, R., Nordlander, S. (1971). Metabolism During Exercise in Patients with Diabetes. In: Pernow, B., Saltin, B. (eds) Muscle Metabolism During Exercise. Advances in Experimental Medicine and Biology, vol 11. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-4609-8_48
Download citation
DOI: https://doi.org/10.1007/978-1-4613-4609-8_48
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4613-4611-1
Online ISBN: 978-1-4613-4609-8
eBook Packages: Springer Book Archive