Muscle ATP, CP, and Lactate in Submaximal and Maximal Exercise

  • J. Karlsson
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 11)


Since the work of Fletcher and Hopkins (4) and of Lundsgaard (14) it is well established from animal experiments that the splitting of the ATP and CF stores (the phosphagens) and the lactate formation are responsible for the anaerobic energy yield of the skeletal muscle. Not until lately the role of these two processes could be evaluated in man during exercise (3, 8, 10). The introduction of a muscle biopsy technique (1) and the development of methods for analysing metabolites on small pieces of skeletal muscle (11) have made it possible to perform more systematic studies also in humans. This paper will focus on the following two problems.
  1. 1.

    Lactate accumulation in the muscles at submaximal and maximal exercise and the concentration gradient for lactate in the muscle.

  2. 2.

    The relationship between oxygen deficit and muscle ATP, CP, and lactate at submaximal and maximal exercise.



Blood Lactate Lactate Concentration Work Load Maximal Exercise Blood Lactate Concentration 
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Copyright information

© Plenum Press, New York 1971

Authors and Affiliations

  • J. Karlsson
    • 1
  1. 1.Department of PhysiologyGymnastik- och idrottshögskolanStockholmSweden

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