Precipitin Cross-Reacitons between Human and Animal J-Chains

  • J. P. Vaerman
  • K. Kobayashi
  • J. F. Heremans


The J-polypeptide chain of polymeric IgA, secretory IgA and/or IgM has been identified in the human (1,2), dog (3), rabbit (1), mouse (4), pig (5), bovine (6), sheep (7), pheasant, toad, catfish (8), shark (9), chicken, rat, but not in tortoise (10) by means of gel electrophoresis in alkaline urea of the reduced-alkylated or S-sulfonated immunoglobulins. The finding of J-chain in such phylogenetically distant species as catfish and shark, points to the primitive character of this polypeptide (8,9).


Trypanosoma Brucei Primitive Character Precipitin Line Putative Biological Function Serological Cross 
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Copyright information

© Plenum Press, New York 1974

Authors and Affiliations

  • J. P. Vaerman
    • 1
  • K. Kobayashi
    • 2
  • J. F. Heremans
    • 1
  1. 1.Dept. of Experimental MedicineUniv. Catholique de LouvainBelgium
  2. 2.Dept of BiochemistryHokkaido UniversitySapporo, HokkaidoJapan

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