Abstract
Gene expression can be assessed by the amounts and types of RNA synthesized at any growth period. No differences were observed in the polynucleotide sequences of DNA from different organs, although large differences were noted among the rapidly labeled RNAs isolated from these tissues (1). The method of molecular hybridization has permitted measurement of the extent of gene activity. This technique has also helped in the identification of tissue-specific RNA by means of competition-hybridization experiments (2,3). All these studies indicated the existence of regulated gene activity as expressed by differential gene expression. Such a regulation has been suggested as a basic molecular event behind the processes of cell differentiation and morphogenesis.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
B. J. McCarthy and B. H. Hoyer. Proc. Natl. Acad. Sci. (USA) 52: 915 - 922 (1964).
E. H. Davidson, M. Crippa, and A. E. Mirsky. Proc. Natl. Acad. Sci. (USA) 60: 152 - 159 (1968).
J. Paul and R. S. Gilmour. J. Mol Biol 34: 305 - 316 (1968).
M. Chamberlin and P. Berg. Proc. Natl Acad. Sci. (USA) 48: 81 - 94 (1962).
R. R. Burgess, A. A. Travers, J. J. Dunn, and E. F. K. Bautz. Nature 221: 43 - 46 (1969).
G. Hartman, K. O. Honikeley, F. Knusel, and J. Nuisch. Biochim. Biophys. Acta 145: 843 - 844 (1967).
S. H. Mizuno, H. Yamazaki, K. Nitta, and H. Umezawa. Biochim. Biophys. Acta 157: 322 - 332 (1968).
S. H. Mizuno, H. Yamazaki, K. Nitta, and H. Umezawa. Biochem. Biophys. Res. Commun. 30: 379 - 385 (1968).
R. C. Huang and J. Bonner. Proc. Natl Acad. Sci. (USA) 48: 1216 - 1222 (1962).
D. L. Wilson and E. P. Geiduschek. Proc. Natl Acad. Sci. (USA) 62: 514 - 520 (1969).
D. Gillespie and S. Spiegelman. J. Mol Biol. 12: 829 - 842 (1965).
A. S. Bhagwat and P. R. Mahadevan. Mol. Gen. Genet. 109: 142 - 151 (1970).
J. Marmur. J. Mol. Biol. 3: 208 - 221 (1961).
K. S. Kirby. Biochem. J. 96: 266 - 269 (1965).
Y. Miyazawa and C. A. Thomas. J. Mol Biol 34: 305 - 316 (1965).
D. E. Kohne. Carnegielnst. Yearbook 67: 310 - 311 (1968).
U. Maitra and J. Hurwitz. Proc. Natl Acad. Sci. (USA) 54: 815 - 822 (1965).
B. M. Alberts, F. J. Amodio, M. Jenkins, E. D. Gutmann, and F. L. Ferris. Cold Spring Harbor Symp. Quant. Biol. 33: 289 - 305 (1968).
R. G. Roeder and W. J. Rutter. Proc. Natl Acad. Sci. (USA) 65: 657 - 682 (1970).
B. J. Davis. Ann. N.Y. Acad. Sci. 121: 404 - 427 (1964).
R. S. Dwivedi, S. K. Dutta, and D. P. Bloch Cell Biol 43: 51 - 58 (1969).
A. D. Riggs, H. Suzuki, and S. Bourgeois. J. Mol Biol 48: 67 - 83 (1970).
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1974 Plenum Press, New York
About this chapter
Cite this chapter
Mahadevan, P.R., Bhagwat, A.S. (1974). Control of Transcription in Neurospora crassa . In: Biswas, B.B., Mandal, R.K., Stevens, A., Cohn, W.E. (eds) Control of Transcription. Basic Life Sciences, vol 3. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-4529-9_18
Download citation
DOI: https://doi.org/10.1007/978-1-4613-4529-9_18
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4613-4531-2
Online ISBN: 978-1-4613-4529-9
eBook Packages: Springer Book Archive