Abstract
This chapter is an extended and updated but largely unreferenced summary of previous reviews (18–22). It discusses the transcriptional controls active during development of the bacteriophage λ. This phage provides a model system which permits critical study of the detailed mechanisms regulating gene expression.
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References
F. R. Blattner and J. E. Dahlberg. RNA synthesis startpoints in bacteriophage λ: Are the promoter and operator transcribed? Nature New Biol. 237: 227 (1972).
F. R. Blattner, J. E. Dahlberg, J. K. Boettiger, M. Fiandt, and W. Szybalski. Distance from a promoter mutation to an RNA synthesis startpoint on bacteriophage λ DNA. Nature New Biol. 237: 232 (1972).
M. Couturier, C. Dambly, and R. Thomas. Control of development in temperate bacteriophages. V. Sequential activation of the viral functions. Mol. Gen. Genet. 120: 231 (1973).
J. E. Dahlberg and F. R. Blattner. Sequence of a self-terminating RNA made near the origin of DNA replication of phage lambda. Fed Proc. 32:664 abst. (1973). In vitro transcription products of lambda DNA: nucleotide sequences and regulatory sites. In C. F. Fox and W. S. Robinson (eds.), Virus Research Academic Press, New York, pp. 533–543 (1973).
N. Davidson and W. Szybalski. Physical and chemical characteristics of lambda DNA. In A. D. Hershey (ed.), The Bacteriophage Lambda, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, pp. 45 - 82 (1971).
W. F. Dove, H. Inokuchi, and W. F. Stevens. Replication control in phage lambda. In A. D. Hershey (ed.), The Bacteriophage Lambda, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, pp. 747 - 771 (1971).
S. Hayes and W. Szybalski. Possible primer for DNA replication in coliphage lambda. Fed. Proc. 32:529 abst. (1973). Synthesis of RNA primer for lambda DNA replication is controlled by phage and host. In B. A. Hamkalo and J. Papaconstantinou (eds.), Molecular Cytogenetics, Plenum Press, New York, pp. 277-283 (1973). Control of short leftward transcripts from the immunity and ori regions in induced coliphage lambda. Molec. Gen. Genet. 126: 275 (1973).
I. Herskowitz and E. Signer. Control of transcription from the r strand of bacteriophage lambda. Cold Spring Harbor Symp. Quant. Biol. 35: 355 (1970).
S. Kumar, E. Calef, and W. Szybalski. Regulation of the transcription of Escherichia coli phage λ by its early genes N and tof. Cold Spring Harbor Symp. Quant. Biol. 35: 331 (1970).
P. Leibowitz, S. M. Weissman, and C. M. Radding. Nucleotide sequence of a ribonucleic acid transcribed in vitro from\phage deoxyribonucleic acid. J. Biol. Chem. 246: 5120 (1971).
H. A. Lozeron, M. L. Funderburgh, J. E. Dahlberg, B. P. Stark, and W. Szybalski. Identity of in vitro and in vivo initiation of phage lambda mRNA: Analysis of in vivo cleavage products. Abst. Ann. Meet. Soc. Microbiol., p. 237 (1972).
A. B. Oppenheim, Z. Neubauer, and E. Calef. The antirepressor: A new element in the regulation of protein synthesis. Nature 226: 31 (1970).
M. Ptashne. Repressor and its action. In A. D. Hershey (ed.), The Bacteriophage Lambda, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, p. 221 (1971).
L. Reichardt and A. D. Kaiser. Control of X repressor synthesis. Proc. Natl. Acad. Sci. (USA) 68: 2185 (1971).
J. F. Roberts. The “rho” factor: Termination and anti-termination in lambda. Cold Spring Harbor Symp. Quant. Biol. 35: 121 (1970).
A. Sugino, S. Hirose, and R. Okazaki. RNA-linked nascent DNA fragments in Escherichia coli. Proc. Natl. Acad. Sci. (USA) 69: 1863 (1972).
W. Szybalski. Initiation and patterns of transcription during phage development. In Canadian Cancer Conference (Proceedings of the Eighth Canadian Cancer Research Conference, Honey Harbor, Ont., 1968), Vol. 8, Pergamon Press, New York, pp. 183 - 215 (1969).
W. Szybalski. Various controls of transcription in coliphage lambda. In L. Silvestri (ed.), RNA Polymerase and Transcription, Lepetit Colloquia on Biology and Medicine 1, North-Holland, Amsterdam, pp. 209 - 217 (1970).
W. Szybalski. Controls of transcription and replication in coliphage lambda. Karl- August-Forster Lectures: Informationsgesteuerte Synthese, Akad. Wiss. Literat. Mainz, Ma them. Naturwiss. Klasse, Vol. 6, F. Steiner Verlag, Wiesbaden, Germany, pp. 1 - 45 (1971).
W. Szybalski. Transcription and replication in E. coli bacteriophage lambda. In L. Ledoux (ed.), Uptake of Informative Molecules by Living Cells, North-Holland, Amsterdam, pp. 59 - 82 (1972).
W. Szybalski, K. Bφvre, M. Fiandt, A. Guha, Z. Hradecna, S. Kumar, H. A. Lozeron, V. M. Maher, Sr., H. J. J. Nijkamp, W. C. Summers, and K. Taylor. Transcriptional controls in developing bacteriophages. J. Cell Physiol. 74: 33 (Suppl. 1) (1969).
W. Szybalski, K. Bφvre, M. Fiandt, S. Hayes, Z. Hradecna, S. Kumar, H. A. Lozeron, H. J. J. Nijkamp, and W. F. Stevens. Transcriptional units and their controls in Escherichia coli phage λ: Operons and scriptons. Cold Spring Harbor Symp. Quant. Biol. 35: 341 (1970).
J. A. Wechsler and J. D. Gross. Escherichia coli mutants temperature-sensitive for DNA synthesis.Mol. Gen. Genet. 113: 273 (1971).
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© 1974 Plenum Press, New York
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Szybalski, W. (1974). Initiation and Regulation of Transcription in Coliphage Lambda. In: Biswas, B.B., Mandal, R.K., Stevens, A., Cohn, W.E. (eds) Control of Transcription. Basic Life Sciences, vol 3. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-4529-9_16
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DOI: https://doi.org/10.1007/978-1-4613-4529-9_16
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