Analysis of Threshold Conditions of Stimulation and the Relationship Between the Threshold Current and Threshold Potential

Abstract

The threshold potential is an important parameter of excitability of the cell. However, its measurement still does not enable the investigator to answer the question whether a stimulus applied to a membrane will be adequate to induce the generation of an action potential. In order to answer this question, as well as the threshold potential, it is also necessary to determine the threshold current, i.e., the smallest strength (density) of a current passing through the membrane which will be adequate to produce its critical depolarization.