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Purification and Characterization of Rabbit Testicular Androgen Binding Protein (ABP)

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Hormonal Regulation of Spermatogenesis

Part of the book series: Current topics in Molecular Endocrinology ((CTME,volume 2))

Abstract

We have reported the presence of an androgen binding protein (ABP) in the cytosols of testis and epididymis of several mammalian species (1). ABP in cytosol preparations has been shown to have a sedimentation coefficient of 4.6 S, an isoelectric point of 4.5–5.2, a Stokes radius of 43 (rabbit) and 47 Å (rat), and a frictional ratio of 1.6, indicating a molecular weight of about 70,000 and 90,000 respectively.

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References

  1. Hansson, V., Ritzen, E.M., French, F.S., and Nayfeh, S.N. in: Handbook of Physiology, Section 7, vol. 5, eds. D.W. Hamilton and R.O. Creep, Amer. Physiol. Soc. 1975, p. 173.

    Google Scholar 

  2. Hansson, V., French, F.S., McLean, W.S., Smith, A.A., Tindall, D.J., Weddington, S.C., Nayfeh, S.N., and Ritzen, E.M. J. Int. Res. Commun. 1: 26, 1973.

    Google Scholar 

  3. Hansson, V., Reusch, E., Trygstad, O., Torgersen, O., French, F.S., and Ritzen, E.M. Nature, New Biol. 246: 56, 1973.

    CAS  Google Scholar 

  4. Hansson, V., Trygstad, O., French, F.S., McLean, W.S., Smith, A.A., Tindall, D.J., Weddington, S.C., Petrusz, P., Nayfeh, S.N., and Ritzen, E.M. Nature 250: 387, 1974.

    Article  PubMed  CAS  Google Scholar 

  5. Hagenas, L., Ritzen, E.M., Ploen, L., Hansson, V., French, F.S., and Nayfeh, S.N. Mol. Cell Endocrinol. May, 1975.

    Google Scholar 

  6. French, F.S., McLean, S.W., Smith, A.A., Tindall, D.J., Weddington, S.C., Petrusz, P., Sar, M., Stumpf, W.E., Nayfeh, S.N., Hansson, V., Trygstad, O., and Ritzen, U.M. in: Hormone Binding and Target Cell Activation in the Testis, eds.: M.L. Dufau and A.R. Means, Plenum Press, 1974, p. 265.

    Google Scholar 

  7. Tindall, D.J., Schrader, W.T., and Means, A.R. in: Hormone Binding and Target Cell Activation in the Testis, eds.: M.L. Dufau and A.R. Means, Plenum Press, New York, 1974, p. 167.

    Google Scholar 

  8. Vernon, R.G., Kopec, B., Fritz, I.B. Mol. Cell Endocrin. 1: 167, 1974.

    Article  CAS  Google Scholar 

  9. Fritz, I.B., Kopec, B., Lam, K., and Vernon, G. in: Hormone Binding and Target Cell Activation in the Testis, eds.: M.L. Dufau and A.R. Means, Plenum Press, New York, 1974, p. 311.

    Google Scholar 

  10. Sanborn, B., Elinton, J.S.H., Steinberger, E., Steinberger, A., and Meistrich, This Volume, p. 293.

    Google Scholar 

  11. French, F.S. and Ritzen, E.M. J. Reprod. Fert. 32: 479, 1973.

    Article  CAS  Google Scholar 

  12. French, F.S. and Ritzen, E.M. Endocrinology 95: 88, 1973.

    Article  Google Scholar 

  13. Ritzen, E.M. and French, F.S. J. Steroid Biochem. 5: 151, 1974.

    Article  PubMed  CAS  Google Scholar 

  14. Weddington, S.C., Hansson, V., French, F.S., Nayfeh, S.N., Ritzen, E.M. and Hagenas, L. Nature 254: 145, 1975.

    Article  PubMed  CAS  Google Scholar 

  15. Hansson, V., Weddington, S.C., Attramadal, A., Naess, O., French, F.S., Nayfeh, S.N., and Ritzen, E.M. This volume, p. 323.

    Google Scholar 

  16. Hansson, V., Ritzen, E.M., French, F.S., Weddington, S.C., Nayfeh, S.N., Reusch, E., and Attramadal, A. Steroids 22: 185, 1973.

    Article  PubMed  CAS  Google Scholar 

  17. Hansson, V., Ritzen, E.M., Weddington, S.C., McLean, W.S., Tindall, D.J., Nayfeh, S.N., and French, F.S. Endocrinology 95: 690, 1974.

    Article  PubMed  CAS  Google Scholar 

  18. Rosner, W.R., Darmstadt, A. Endocrinology 92: 1700, 1973.

    Article  PubMed  CAS  Google Scholar 

  19. Mahoudeau, T.A. and Corvol, P. Endocrinology 92: 1113, 1973.

    Article  PubMed  CAS  Google Scholar 

  20. Hansson, V., Ritzen, E.M., French, F.S., Weddington, S.C., and Nayfeh, S.N. Mol. Cell Endocrinol., May, 1975.

    Google Scholar 

  21. Ritzen, E.M., French, F.S., Weddington, S.C., Nayfeh, S.N., and Hansson, V. J. Biol. Chem. 249: 6597, 1974.

    CAS  Google Scholar 

  22. Means, A.R. and Tindall, D.J., this volume, p. 383.

    Google Scholar 

  23. Webber, K. and Osborn, M. J. Biol. Chem. 244: 16, 1969.

    Google Scholar 

  24. Chambers, R.E. and Clamp, J.R. Biochem. J. 125: 1009, 1971.

    PubMed  CAS  Google Scholar 

  25. Sletten, K. and Husby, G. Eur. J. Biochem. 41: 117, 1974.

    Article  PubMed  CAS  Google Scholar 

  26. Weddington, S.C., Brandtzaeg, P., Hansson, V., French, F.S., Petrusz, P., Nayfeh, S.N., and Ritzen, E.M. Nature, 1975, in press.

    Google Scholar 

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Author information

Authors and Affiliations

  1. Institute of Pathology, Rikshospitalet, Oslo, Norway

    S. C. Weddington, P. Brandtzaeg, K. Sletten, T. Christensen & V. Hansson

  2. Departments of Pediatrics, Biochemistry and The Laboratories for Reproductive Biology, University of North Carolina, School of Medicine, Chapel Hill, N.C., USA

    F. S. French, P. Petrusz & S. N. Nayfeh

  3. Pediatric Endocrinology Unit, Clinical Research Laboratory, Karolinska Sjukhuset, Stockholm, Sweden

    E. M. Ritzen

Authors
  1. S. C. Weddington
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  2. P. Brandtzaeg
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  3. K. Sletten
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  4. T. Christensen
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  5. V. Hansson
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  6. F. S. French
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  7. P. Petrusz
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  8. S. N. Nayfeh
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  9. E. M. Ritzen
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Editor information

Editors and Affiliations

  1. University of Carolina, USA

    Frank S. French

  2. Rikshospitalet, Oslo, Norway

    Vidar Hansson

  3. Karolinska Sjukhuset, Stockholm, Sweden

    E. Martin Ritzen

  4. University of North Carolina, USA

    Shihadeh N. Nayfeh

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© 1975 Plenum Press, New York

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Weddington, S.C. et al. (1975). Purification and Characterization of Rabbit Testicular Androgen Binding Protein (ABP). In: French, F.S., Hansson, V., Ritzen, E.M., Nayfeh, S.N. (eds) Hormonal Regulation of Spermatogenesis. Current topics in Molecular Endocrinology, vol 2. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-4440-7_31

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  • DOI: https://doi.org/10.1007/978-1-4613-4440-7_31

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-4442-1

  • Online ISBN: 978-1-4613-4440-7

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