Distribution of Steroids, Steroid Production and Steroid Metabolizing Enzymes in Rat Testis

  • H. J. van der Molen
  • J. A. Grootegoed
  • M. J. de Greef-Bijleveld
  • F. F. G. Rommerts
  • G. J. van der Vusse
Part of the Current topics in Molecular Endocrinology book series (CTME, volume 2)

Abstract

In the present paper some results are presented on:
  1. 1.

    the occurrence and age dependence of some enzyme activities in whole rat testis tissue as related to the development of spermatogenesis;

     
  2. 2.

    enzymes for steroid metabolism in isolated dissected rat testis tissue fractions with special emphasis on the age dependent variations of steroid 5α-reductase activity, and;

     
  3. 3.

    concentrations and production of steroids in isolated cellular and subcellular fractions of rat testis. These data are presented mainly to illustrate the limitation of results on enzyme activities, steroid concentrations and steroid production in total testis tissue and in isolated tissue fractions for the understanding of the regulation of specific processes in particular cell types, such as the regulation of spermatogenesis.

     

Keywords

Lactate Carboxyl Germinal Testosterone Progesterone 

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Copyright information

© Plenum Press, New York 1975

Authors and Affiliations

  • H. J. van der Molen
    • 1
  • J. A. Grootegoed
    • 1
  • M. J. de Greef-Bijleveld
    • 1
  • F. F. G. Rommerts
    • 1
  • G. J. van der Vusse
    • 1
  1. 1.Department of Biochemistry (Division of Chemical Endocrinology)Medical Faculty, Erasmus University RotterdamRotterdamThe Netherlands

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