The Effect of Total, Partial, and Stage Sleep Deprivation on EEG Patterns and Performance

  • Laverne C. Johnson

Abstract

Less than 20 years ago, few scientists would have considered sleep an appropriate topic for a symposium concerning behavior and brain electrical activity. Though some investigators had studied brain electrical activity during sleep (Loomis, Harvey, and Hobart 1937), sleep was hardly conceived as a fruitful period for behavioral research. Sleep was regarded as a quiet period, even referred to as a state of unconsciousness. We are now aware of the richness of sleep behavior, and perhaps in no other area are brain electrical activity and behavior so closely coupled as in a person going from awake to the drowsy period of stage 1, then on to sleep identified by the brain’s unique signature, sleep spindles and bursts of K-complexes. The sleep spindles and large-amplitude delta rhythms of stages 2, 3, and 4 (nonREM sleep) periodically give way to the low-voltage electroencephalographic (EEG) activity with associated rapid eye movements (REMs) reflecting the characteristic 90–100 minute cycle of REM-nonREM sleep. This cycle and the unique behavioral and physiological activity associated with each phase are tracked nightly in laboratories throughout the world by means of electroencephalographic recordings of brain electrical activity. Not only is this electrical activity of the sleeping brain a universal human phenomenon, but comparable activity is also present in nonhuman species. Clearly sleep is an excellent area to study the relation between brain electrical activity and behavior.

Keywords

Fatigue Depression Schizophrenia Respiration Posit 

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References

  1. Agnew, H.W., Jr., and Webb, W.B. 1972. Measurement of sleep onset by EEG criteria. American Journal of EEG Technology 12:127.Google Scholar
  2. Agnew, H.W., Jr., Webb, W.B., and Williams, R.L. 1967. Comparison of stage four and 1-REM sleep deprivation. Percept. Mot. Skills 24:851.PubMedCrossRefGoogle Scholar
  3. Armington, J.C., and Mitnick, L.L. 1959. Electroencephalogram and sleep deprivation. J. Appl. Physiol. 14:247.Google Scholar
  4. Berger, R.J., and Oswald, I. 1962. Effects of sleep deprivation on behaviour, subsequent sleep, and dreaming. J. Ment. Sci. 108:457.PubMedGoogle Scholar
  5. Berger, R.J., Walker, J.M., Scott, T.D., Magnuson, L.J., and Pollack, S.L. 1971. Diurnal and nocturnal sleep stage patterns following sleep deprivation. Psychonomic Science 23:273.Google Scholar
  6. Bliss, E.L., Clark, L.D., and West, C.D. 1959. Studies of sleep deprivation—Relationship to schizophrenia. Arch. Neurol. Psychiatry 81:348.Google Scholar
  7. Brauchi, J.T., and West, L.J. 1959. Sleep deprivation. JAMA 171:11.Google Scholar
  8. Buck, L., and Gibbs, C.B. 1972. Sleep loss and information processing. In W.P. Colquhoun (ed.), Aspects of Human Efficiency, p. 47. London: English Universities Press.Google Scholar
  9. Cartwright, R.D., Monroe, L.J., and Palmer, C. 1967. Individual differences in response to REM deprivation. Arch. Gen. Psychiatry 16:297.PubMedGoogle Scholar
  10. Chernik, D.A. 1972. Effect of REM sleep deprivation on learning and recall by humans. Percept. Mot. Skills 34:283.PubMedCrossRefGoogle Scholar
  11. Clemes, S.R., and Dement, W.C. 1967. Effect of REM sleep deprivation on psychological functioning. J. Nerv. Ment. Dis. 144:485.PubMedCrossRefGoogle Scholar
  12. Colquhoun, W.P. (ed.) 1972. Aspects of Human Efficiency. London: English Universities Press.Google Scholar
  13. Corcoran, D.W.J. 1962. Individual differences after loss of sleep. Unpublished doctoral dissertation, University of Cambridge, Cambridge. England.Google Scholar
  14. Dement, W. 1960. The effect of dream deprivation. Science 131:1705.PubMedCrossRefGoogle Scholar
  15. Dement, W.C. 1965. Recent studies on the biological role of rapid eye movement sleep. Am. J. Psychiatry 122:404.PubMedGoogle Scholar
  16. Dement, W., and Greenberg, S. 1966. Changes in total amount of stage four sleep as a function of partial sleep deprivation. Electroencephalogr. Clin. Neurophysiol. 20:523.PubMedCrossRefGoogle Scholar
  17. Empson, J.A.C., and Clarke, P.R.F. 1970. Rapid eye movements and remembering. Nature 227:287.PubMedCrossRefGoogle Scholar
  18. Fisher, C., and Dement, W.C. 1963. Studies on the psychopathology of sleep and dreams. Am. J. Psychiatry 119:1160.PubMedGoogle Scholar
  19. Freeman, G.L. 1932. Compensatory reinforcements of muscular tension subsequent to sleep loss. J. Exp. Psychol. 15:267.CrossRefGoogle Scholar
  20. Gulevich, G., Dement, W., and Johnson, L. 1966. Psychiatric and EEG observations on a case of prolonged (264 hours) wakefulness. Arch. Gen. Psychiatry15:29.PubMedGoogle Scholar
  21. Hamilton, P., Wilkinson, R.T., and Edwards, R.S. 1972. A study of four days partial sleep deprivation. In W.P. Colquhoun (ed.), Aspects of Human Efficiency, p. 101. London: English Universities Press.Google Scholar
  22. Hartmann, E., Baekeland, F., Zwilling, G., and Hoy, P. 1971. Sleep need: How much sleep and what kind? Am. J. Psychiatry 127:1001.PubMedGoogle Scholar
  23. Hoddes, E., Zarcone, V., Smythe, H., Phillips, R., and Dement, W.C. 1973. Quantification of sleepiness: A new approach. Psychophysiology 10:431.PubMedCrossRefGoogle Scholar
  24. Johnson, L.C. 1969. Psychological and physiological changes following total sleep deprivation. In A. Kales (ed.), Sleep: Physiology & Pathology, p. 206. Philadelphia: Lippincott.Google Scholar
  25. Johnson, L.C. 1973. Are stages of sleep related to waking behavior? Am. Sci. 61:326.PubMedGoogle Scholar
  26. Johnson, L.C, and MacLeod, W.L. 1973. Sleep and awake behavior during gradual sleep reduction. Percept. Mot. Skills 36:87.PubMedCrossRefGoogle Scholar
  27. Johnson, L., Naitoh, P., Lubin, A., and Moses, J. 1972. Sleep stages and performance. In W.P. Colquhoun (ed.), Aspects of Human Efficiency, p. 81. London: English Universities Press.Google Scholar
  28. Johnson, L.C, Naitoh, P., Moses, J.M., and Lubin, A. 1974. Interaction of REM deprivation and stage 4 deprivation with total sleep loss: Experiment 2. Psychophysiology 11:147.PubMedCrossRefGoogle Scholar
  29. Johnson, L.C, Slye, E.S., and Dement, W. 1965. Electroencephalographic and autonomic activity during and after prolonged sleep deprivation. Psychosom. Med. 27:415.PubMedGoogle Scholar
  30. Jones, H.S., and Oswald, I. 1968. Two cases of healthy insomnia. Electroencephalogr. Clin. Neurophysiol. 24:378.PubMedCrossRefGoogle Scholar
  31. Kales, A., Hoedemaker, F.S., Jacobson, A., and Lichtenstein, E.L. 1964. Dream deprivation: An experimental reappraisal. Nature 204:1337.PubMedCrossRefGoogle Scholar
  32. Kollar, E.J., Pasnau, R.D., Rubin, R.T., Naitoh, P., Slater, G.G., and Kales, A. 1969. Psychological, psychophysiological, and biochemical correlates of prolonged sleep deprivation. Am. J. Psychiatry 126:488.PubMedGoogle Scholar
  33. Laird, D.A., and Wheeler, W. 1926. What it costs to lose sleep. Indust. Psychol. 1:694.Google Scholar
  34. Laslett, H.R. 1928. Experiments on the effects of the loss of sleep. J. Exp. Psychol. 11:370.CrossRefGoogle Scholar
  35. Loomis, A.L., Harvey, E.N., and Hobart, G.A. III. 1937. Cerebral states during sleep, as studied by human brain potentials. J. Exp. Psychol. 21:127.CrossRefGoogle Scholar
  36. Lubin, A. 1967. Performance under sleep loss and fatigue. In S.S. Kety, E.V. Evarts, and H.L. Williams (eds.), Sleep and Altered States of Consciousness, p. 506. Baltimore: Williams & Wilkins.Google Scholar
  37. Lubin, A., Moses, J.M., Johnson, L.C, and Naitoh, P. 1974. The recuperative effects of REM sleep and stage 4 sleep on human performance after complete sleep loss: Experiment 1. Psychophysiology 11:133.PubMedCrossRefGoogle Scholar
  38. Luby, E.D., Frohman, C.E., Grisell, J.L., Lenzo, J.E., and Gottlieb, J.S. 1960. Sleep deprivation: Effects on behavior, thinking, motor performance, and biological energy transfer system. Psychosom. Med. 22:182.PubMedGoogle Scholar
  39. Luby, E.D., and Gottlieb, J.S. 1966. Sleep deprivation. In S. Arieti (ed.), American Handbook of Psychiatry, vol. 3, p. 406. New York: Basic Books.Google Scholar
  40. Malmo, R.B., and Surwillo, W.W. 1960. Sleep deprivation: Changes in performance and physiological indicants of activation. Psychol. Monogr. 74 (15, Whole No. 502).Google Scholar
  41. McNair, D.M., Lorr, M., and Droppleman, L.F. 1971 Profile of Mood States. San Diego, Calif.: Educational and Industrial Testing Service.Google Scholar
  42. McReynolds, P. 1954. Rorschach concept evaluation technique. J. Project. Techn. 18:60.PubMedCrossRefGoogle Scholar
  43. Meddis, R., Pearson, A.J.D., and Langford, G. 1973. An extreme case of healthy insomnia. Electroencephalogr. Clin. Neurophysiol. 35:213.PubMedCrossRefGoogle Scholar
  44. Moore, L.M., Jenkins, M., and Barker, L. 1922. Relation of number of hours of sleep to muscular efficiency. Am. J. Physiol. 59:471.Google Scholar
  45. Moses, J.M., Johnson, L.C., Naitoh, P., and Lubin, A. Sleep stage deprivation and total sleep loss: Effects on sleep behavior. Psychophysiology, (in press).Google Scholar
  46. Naitoh, P. 1969. Sleep loss and its effects on performance. Navy Medical Neuropsychiatric Research Unit, San Diego, Calif., Report No. 68–3.Google Scholar
  47. Naitoh, P., Johnson, L.C, and Austin, M. 1971. Aquanaut sleep patterns during Tektite I: A 60-day habitation under hyperbaric nitrogen saturation. Aerosp. Med. 42:69.PubMedGoogle Scholar
  48. Naitoh, P., Johnson, L.C, and Lubin, A. 1971. Modification of surface negative slow potential (CNV) in the human brain after total sleep loss. Electroencephalogr. Clin. Neurophysiol. 30:17.PubMedCrossRefGoogle Scholar
  49. Naitoh, P., Kales, A., Kollar, E.J., Smith, J.C, and Jacobson, A. 1969. Electroencephalographic activity after prolonged sleep loss. Electroencephalogr. Clin. Neurophysiol. 27:2.PubMedCrossRefGoogle Scholar
  50. Naitoh, P., Pasnau, R.O., and Kollar, E.J. 1971. Psychophysiological changes after prolonged deprivation of sleep. Biol. Psychiatry 3:309.PubMedGoogle Scholar
  51. Naitoh, P., and Townsend, R.E. 1970. The role of sleep deprivation research in human factors. Human Factors 12:575.PubMedGoogle Scholar
  52. Omwake, K.T. 1932. Effect of varying periods of sleep on nervous stability. J. Appl. Psychol. 16:623.CrossRefGoogle Scholar
  53. Pasnau, R.O., Naitoh, P., Stier, S., and Kollar, E.J. 1968. The psychological effects of 205 hours of sleep deprivation. Arch. Gen. Psychiatry 18:496.PubMedGoogle Scholar
  54. Robinson, E.S., and Richardson-Robinson, F. 1922. Effects of loss of sleep. II. J. Exp. Psychol. 5:93.CrossRefGoogle Scholar
  55. Sampson, H. 1965. Deprivation of dreaming sleep by two methods. I. Compensatory REM time. Arch. Gen. Psychiatry 13:79.PubMedGoogle Scholar
  56. Sampson, H. 1966. Psychological effects of deprivation of dreaming sleep. J. Nerv. Ment. Dis. 143:305.PubMedCrossRefGoogle Scholar
  57. Smith, M.A. 1916. A contribution to the study of fatigue. Br. J. Psychol. 8:327.Google Scholar
  58. Snyder, F. 1963. The new biology of dreaming. Arch. Gen. Psychiatry 8:381.PubMedGoogle Scholar
  59. Snyder, F., and Scott, J. 1972. The psychophysiology of sleep. In N.S. Greenfield and R.A. Sternbach (eds.), Handbook of Psychophysiology, p. 645. New York: Holt, Rinehart & Winston.Google Scholar
  60. Townsend, R.E., Johnson, L.C, and Muzet, A. 1973. Effects of long term exposure to tone pulse noise on human sleep. Psychophysiology 10:369.PubMedCrossRefGoogle Scholar
  61. Tyler, D.B., Goodman, J., and Rothman, T. 1947. The effect of experimental insomnia on the rate of potential changes in the brain. Am. J. Physiol. 149:185.PubMedGoogle Scholar
  62. Van Ormer, E.B. 1932. Retention after intervals of sleep and waking. Arch. Psychol. 49:5.Google Scholar
  63. Webb, W.B. 1969. Partial and differential sleep deprivation. In A. Kales (ed.), Sleep: Physiology & Pathology, p. 221. Philadelphia: Lippincott.Google Scholar
  64. Webb, W.B. 1972. General discussion, Proceedings of NATO Scientific Affairs Division Conference, Strasbourg, France, July 13-17, 1970. In W.P. Colquhoun (ed.), Aspects of Human Efficiency, p. 129. London: English Universities Press.Google Scholar
  65. Webb, W.B., and Agnew, H.W., Jr. 1965. Sleep: Effects of a restricted regime. Science 150:1745.PubMedCrossRefGoogle Scholar
  66. Webb, W.B., and Agnew, H.W., Jr. The effects of a chronic limitation of sleep length. Psychophysiology, (in press).Google Scholar
  67. Webb, W.B., and Friel, J. 1971. Sleep stage and personality characteristics of “natural” long and short sleepers. Science 171:587.PubMedCrossRefGoogle Scholar
  68. West, L.J., Janszen, H.H., Lester, B.K., and Cornelisoon, F.S. 1962. The psychosis of sleep deprivation. Ann. N.Y. Acad. Sci. 96:66.PubMedCrossRefGoogle Scholar
  69. Wilkinson, R.T. 1961. Interaction of lack of sleep with knowledge of results, repeated testing, and individual differences. J. Exp. Psychol. 62:263.PubMedCrossRefGoogle Scholar
  70. Wilkinson, R.T. 1969. Sleep deprivation: Performance tests for partial and selective sleep deprivation. In L.E. Abt and B.F. Riess (eds.), Progress in Clinical Psychology, vol. 8. Dreams and Dreaming, p. 28. New York: Grune & Stratton.Google Scholar
  71. Wilkinson, R.T. 1972. Sleep deprivation—eight questions. In W.P. Colquhoun (ed.), Aspects of Human Efficiency, p. 25. London: English Universities Press.Google Scholar
  72. Wilkinson, R.T., Edwards, R.S., and Haines, E. 1966. Performance following a night of reduced sleep. Psychonomic Science 5:471.Google Scholar
  73. Williams, H.L., Gieseking, C.F., and Lubin, A. 1966. Some effects of sleep loss on memory. Percept. Mot. Skills 23:1287.PubMedCrossRefGoogle Scholar
  74. Williams, H.L., Granda, A.M., Jones, R.C., Lubin, A., and Armington, J.C. 1962. EEG frequency and finger pulse volume as predictors of reaction time during sleep loss. Electroencephalogr. Clin. Neurophysiol. 14:64.PubMedCrossRefGoogle Scholar
  75. Williams, H.L., Hammack, J.T., Daly, R.L., Dement, W.C, and Lubin, A. 1964. Responses to auditory stimulation, sleep loss and the EEG stages of sleep. Electroencephalogr. Clin. Neurophysiol. 16:269.PubMedCrossRefGoogle Scholar
  76. Williams, H.L., Kearney, O.F., and Lubin, A. 1965. Signal uncertainty and sleep loss. J. Exp. Psychol. 69:401.PubMedCrossRefGoogle Scholar
  77. Williams, H.L., and Lubin, A. 1967. Speeded addition and sleep loss. J. Exp. Psychol. 73:313.CrossRefGoogle Scholar
  78. Williams, H.L., Lubin, A., and Goodnow, J.J. 1959. Impaired performance with acute sleep loss. Psychol. Monogr. 73 (14, Whole No. 484).Google Scholar
  79. Williams, H.L., and Williams, C.L. 1966. Nocturnal EEG profiles and performance. Psychophysiology 3:164.PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1975

Authors and Affiliations

  • Laverne C. Johnson
    • 1
  1. 1.Navy Medical Neuropsychiatric Research UnitSan DiegoUSA

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