Abstract
Systemic pretreatment of mice with Corynebacterium parvum vaccine (CP) exerts a powerful adjuvant effect on antibody production against various T-cell-dependent (Biozzi et al., 1966) and -independent (Howard et al, 1973a) antigens. Previous work has provided evidence that this involves stimulation of B cells at a time when cell-mediated immunity, but not helper, activities of T cells are inhibited. It has been suggested that this adjuvant action of CP on B cells, like the suppressive effect on T cells, is mediated via activated macrophages (Howard et al., 1973b).
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References
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© 1975 Plenum Press, New York
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Wiener, E. (1975). Analysis of the Corynebacterium parvum Adjuvant Effects at the Cellular and Subcellular Levels. In: Halpern, B. (eds) Corynebacterium Parvum. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-4428-5_6
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DOI: https://doi.org/10.1007/978-1-4613-4428-5_6
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4613-4430-8
Online ISBN: 978-1-4613-4428-5
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