Comparative Effects of Various Strains of Corynebacterium parvum and Other Prophylactic Agents on Tumor Development in Animals

  • Heinrich Wrba


After the publication by Halpern et al. (1966) of an article on the tumor-inhibiting effect of Corynebacterium parvum (Cp), we undertook a large series of similar experiments. At that time, a strain of Cp from the American Type Culture Collection (ATCC) was at our disposal.* An exact repetition of the experiments as published produced negative results in our laboratory. It was therefore decided to investigate growth inhibition on a spectrum of tumors.


Formalin Lymphoma Leukemia Sarcoma Corynebacterium 


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  1. Halpern, B. N., Biozzi, G., Stiffel, C., and Mouton, D. (1966). Inhibition of tumor growth by administration of killed Corynebacterium parvum. Nature (Loud.) 212: 853–854.CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1975

Authors and Affiliations

  • Heinrich Wrba
    • 1
  1. 1.Institute for Cancer Research of the University of ViennaAustria

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