Abstract
In defined situations Corynebacterium parvum has an inhibitory effect on tumor growth. In our experiments, 0.2 ml of intraperitoneal C. parvum, given on two consecutive days, caused inhibition of Ehrlich’s ascitic tumor (Fig. 1) and similar effects were observed in CBA mice given S.37 ascites sarcoma (Fig. 2). The growth of subcutaneous Lewis lung tumor in male mice was inhibited by intravenous or intraperitoneal C. parvum, but contralateral subcutaneous C. parvum was ineffective (Fig. 3). Intravenous and intraperitoneal C. parvum decreased pulmonary metastases from the tumor (Table I).
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© 1975 Plenum Press, New York
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Castro, J.E., Sadler, T.E. (1975). An Analysis of the Antitumor Effects of Corynebacterium parvum . In: Halpern, B. (eds) Corynebacterium Parvum. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-4428-5_28
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DOI: https://doi.org/10.1007/978-1-4613-4428-5_28
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4613-4430-8
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