Combination Chemotherapy of Advanced Hodgkin’s Disease with Adriamycin, DTIC, CCNU, and Bleomycin
Eighteen patients with advanced Hodgkin’s disease who were refractory to previous MOPP-therapy were entered into a new treatment protocol, consisting of adriamycin, DTIC, bleomycin and CCNU. Three patients who never had responded to previous chemotherapy did not respond to the new regimen. Two complete remissions and 11 partial remissions were achieved in a group of 15 patients with prior response to MOPP-therapy, and only 2 had progressive disease.
KeywordsToxicity Thrombocytopenia Bleomycin Adriamycin CCNU
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