The four classes of immunosuppressive agents which are most widely used clinically are thiopurines (6-mercaptopurine, azathioprine), alkylating agents (cyclophosphamide, chlorambucil), corticosteroids and antilymphocyte serum. Their effects differ very much from one another and these differences in activity are probably related to differences in target cells.
KeywordsImmunosuppressive Agent Alkylating Agent Tumour Immunity Allograft Survival Mediate Immune Reaction
- All references will be found in: Bach J.F. (1975). The mode of action of immunosuppressive agents. North Holland-American Elsevier, Vol. 41. Amsterdam, New York, 379P.Google Scholar