In Vitro Screening of Cytotoxic Substances Using Different Tumour Cells
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A three-step system for the screening of potential cytostatics was devised. In vitro criteria used in the first two steps of the screening allow the finding of general cytotoxic substances and to choose from them for final evaluation in vivo those in which the specific effects on tumour cells were observed. The results achieved in this system are demonstrated on the PSX-1 antibiotic.
KeywordsCytopathic Effect Screening System Tumour Cell Implantation Cytic Leukaemia Cytotoxic Substance
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