Experience with ICRF 159 and Radiotherapy in Combination in the Treatment of Soft Tissue Sarcomas
The response of soft tissue sarcomas to radiotherapy treatment is disappointing. Local recurrence of tumour within a year of irradiation occurs in 50% cases or more in most1 published series. Haematogenous dissemination of tumour is a frequent occurrence and occurs early in the disease. Local recurrence of tumour increases the risk of blood borne metastases which are reported in 65% of such cases. However, radiotherapy has been advocated in the 4 treatment of this group of tumours by a number of authors 2,3, either as an adjunct to surgery or on its own. High doses of radiation to large volumes of tissue are required if there is to be any hope of controlling the tumours.
KeywordsLocal Recurrence Hiatus Hernia Soft Tissue Sarcoma Radical Radiotherapy Radiosensitising Effect
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