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Lymphocyte Mediators, Activated Macrophages, and Tumor Immunity

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Molecular and Biological Aspects of the Acute Allergic Reaction

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Abstract

In the introduction to the paper concerned with lymphocyte mediators which appeared in the Proceedings of the 2nd International Symposium on the Biochemistry of Acute Allergic Reactions, an explanation was given to justify the inclusion of this topic in such a meeting (1). Five years later, such an apologia seems unnecessary. Despite the many differences in the mechanisms of acute and delayed immunologic reactions, there are now known interactions and some similarities between the two, and more will undoubtedly be found in the future. For instance, among the many mediators produced by lymphocytes when stimulated by antigen are substances which regulate the production of antibody. More specifically, antigen-triggered T lymphocytes can produce both helper and suppressor substances which affect the production of IgE by B cells (2–4).

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Author information

Authors and Affiliations

  1. Harvard Medical School, Robert B. Brigham Hospital, 02120, Boston, Massachusetts, USA

    John R. David

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  1. John R. David
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Editors and Affiliations

  1. University Hospital, Uppsala, Sweden

    S. G. O. Johansson

  2. Karolinska Institute, Stockholm, Sweden

    Kjell Strandberg  & Börje Uvnäs  & 

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© 1976 Plenum Press, New York

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David, J.R. (1976). Lymphocyte Mediators, Activated Macrophages, and Tumor Immunity. In: Johansson, S.G.O., Strandberg, K., Uvnäs, B. (eds) Molecular and Biological Aspects of the Acute Allergic Reaction. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-4304-2_22

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  • DOI: https://doi.org/10.1007/978-1-4613-4304-2_22

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-4306-6

  • Online ISBN: 978-1-4613-4304-2

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