Calcium Stone Disease: Pilot Study of Hormonal Response to Meal and Hypoglycemia

  • P. O. Schwille
  • R. Thun
  • N. M. Samberger


The metabolic steps initiating high rate crystalluria, increased crystal size and altered tubular transport characteristics in stone formers are unknown. Functional relationships are believed to exist among either hypercalciuric (HC) idiopathic or hyperparathyroid (HPT) stone formation and the latter and peptic ulcer disease (1,2). In this study efforts have been made to evaluate group differences as regards secretory dynamics of gastrin (G), A-cell glucagon (pGl) and parathyroid hormone (PTH) whose interactions are partially documented in animals and humans (1,3,4). The results show that endocrine gut signals can be linked to symptoms such as hypercalciuria and hyperphosphaturia.


Peptic Ulcer Disease Calcium Stone Secretory Dynamic Urinary cAMP Parathyroid Activity 
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Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • P. O. Schwille
    • 1
  • R. Thun
    • 1
  • N. M. Samberger
    • 1
  1. 1.Department of Surgery and Urology, Mineral Metabolism and Hormone LaboratoryUniversity of ErlangenErlangenGermany

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