Abstract
The complexation of calcium ion (Ca++) by monophosphonates (MP)* and diphosphonates (DP)* has been studied under conditions of physiological pH, temperature and ionic strength by the method of Schubert (1). In this procedure, the competition between the anionic ligand and a cation exchange resin for Ca++ is determined. Thus, with a fixed amount of Ca++, Ca45 and Dowex 50 WX4 resin 5 to 10 increments of DP were added to compete increasingly with the resin for Ca++.
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References
Schubert, J., J.Physiol.Chem. 56: 113–117 (1952).
Gosselin, R.E. and Coghlan, E.R., Arch.Biochem.Biophys. 45: 301–311 (1953).
Di Stefano, V. and Neuman, W.F., J.Biol.Chem. 200: 759–763 (1953).
Curry, J.D., Nicholson, D.A. and Quimby, O.T. “Oligophosphonates” in Topics in Phosphorus Chemistry (ed. by E.J. Griffith and M. Grayson) Vol. VII, pp. 37–102, John Wiley and Sons Inc., New York, N.Y., 1972.
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© 1976 Plenum Press, New York
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Neuman, W.F. (1976). The Complexation of Calcium Ion by Diphosphonates. In: Fleisch, H., Robertson, W.G., Smith, L.H., Vahlensieck, W. (eds) Urolithiasis Research. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-4295-3_38
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DOI: https://doi.org/10.1007/978-1-4613-4295-3_38
Publisher Name: Springer, Boston, MA
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